Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Francis Wiener"'
Publikováno v:
Genes & Cancer. 1:847-858
Chromosome 11 aberrations constitute the second most frequent chromosomal aberration in mouse plasmacytomas (PCTs) in which both the myc and abl oncogenes are constitutively expressed. In these tumors, previous G-banding studies had revealed numerica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaae7640bc2a83c26a5dab5bbf6255f
https://doi.org/10.1177/1947601910382897
https://doi.org/10.1177/1947601910382897
Publikováno v:
Genes, Chromosomes and Cancer. 42:416-426
The location of the Myc and immunoglobulin (Ig) loci on metacentric Robertsonian (Rb) fusion chromosomes may affect the development of mouse plasmacytomas (Pcts) by changing the probability with which chromosomal Myc-Ig translocations occur. To test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa075ad1fa59662da96468823198ba
https://doi.org/10.1002/gcc.20149
https://doi.org/10.1002/gcc.20149
Publikováno v:
Chromosome Research. 12:777-785
Previous work has demonstrated that chromosome 11 is trisomic or shows a duplicated region encompassing the E1/E2 band of chromosome 11 in 90% of v-abl/myc-induced plasmacytomas (Wiener et al. 1995). In the present report, we have studied BALB/c PreB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdda12489379f5d41466f20c6e58190
https://doi.org/10.1007/s10577-005-5264-z
https://doi.org/10.1007/s10577-005-5264-z
Autor:
Sabine Mai, Francis Wiener
Publikováno v:
Chromosome Research. 10:239-251
Mouse plasmacytomas (PCTs) are characterized by c-myc-activating translocations that juxtapose c-myc on chromosome 15 onto one of the immunoglobulin loci (IgH on chromosome 12, Igκ on chromosome 6, or Igλ on chromosome 16). To assess the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d26c893779ef4adc5a8da11a6a20d67
https://doi.org/10.1023/a:1015200307448
https://doi.org/10.1023/a:1015200307448
Publikováno v:
Proceedings of the National Academy of Sciences. 96:13967-13972
The induced expression of c-Myc in plasmacytomas in BALB/c mice is regularly associated with nonrandom chromosomal translocations that juxtapose the c -myc gene to one of the Ig loci on chromosome 12 ( IgH ), 6 ( IgK ), or 16 ( IgL ). The DCPC21 plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d04fc899cfce8503980fbb8acb33ee
https://doi.org/10.1073/pnas.96.24.13967
https://doi.org/10.1073/pnas.96.24.13967
Publikováno v:
Carcinogenesis. 20:529-538
Dysregulation of the c-myc gene by chromosomal translocation in >95% of murine plasmacytomas (MPCs) is an obligatory requirement for the transformation of B lymphocytes into MPCs. However, it is still unknown whether sIg+ B cells or differentiated pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037c33bf5139321dce4b631293896088
https://doi.org/10.1093/carcin/20.4.529
https://doi.org/10.1093/carcin/20.4.529
Publikováno v:
European Journal of Cancer. 33:479-485
Sixty per cent of BALB/cAnPt mice injected intraperitoneally (i.p.) with tetramethylpentadecane (pristane) develop plasmacytomas (PCs), whereas less than 10% of BALB/cJ develop such tumours. Most other mouse strains are completely resistant. Resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d024b518be97cbb103970c06881940a
https://doi.org/10.1016/s0959-8049(97)89025-9
https://doi.org/10.1016/s0959-8049(97)89025-9
Autor:
Francis Wiener, Christiaan H. Righolt, Cheryl Taylor-Kashton, Yuval Garini, Sabine Mai, Jana Harizanova, Ian T. Young, Bart J. Vermolen
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 79(4)
Chromosome positions within the nucleus of mammalian cells are nonrandom and it is assumed that chromosomal neighborhoods affect the probability of translocations. Four chromosomes can be involved in c-myc-activating chromosomal translocations in mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db08bc2576f7ea559182859e7d92ced
https://pubmed.ncbi.nlm.nih.gov/21387545
https://pubmed.ncbi.nlm.nih.gov/21387545
Autor:
Francis Wiener, Michael Potter
Publikováno v:
Carcinogenesis. 13:1681-1697
Three model systems of plasmacytomagenesis that are associated with mutations that affect c-myc transcription were discussed. Plasmacytoma induction by chronic peritoneal irritation induced by non-metabolized paraffin oils or plastic objects is stron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd4b7fa62e7a4d11d1ecaabb9644b03
https://doi.org/10.1093/carcin/13.10.1681
https://doi.org/10.1093/carcin/13.10.1681
Autor:
Tadamitsu Kishimoto, Toshio Hirano, Francis Wiener, Santiago Silva, Hiroyuki Sugiyama, George Klein, Magda Babonits
Publikováno v:
International Journal of Cancer. 48:234-238
Activation of c-myc by juxtaposition to an immunoglobulin locus and introduction of the v-abl oncogene act synergistically in generating a mouse plasmacytoma (PC). The question arose whether the effect of v-abl could be attributed to a deregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb96729636ba5e2c6c4f7e71dc8f580f
https://doi.org/10.1002/ijc.2910480214
https://doi.org/10.1002/ijc.2910480214