Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Francis W. Hunter"'
Autor:
Tet Woo Lee, Dean C. Singleton, Julia K. Harms, Man Lu, Sarah P. McManaway, Amy Lai, Moana Tercel, Frederik B. Pruijn, Andrew M. J. Macann, Francis W. Hunter, William R. Wilson, Stephen M. F. Jamieson
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1885-1903 (2024)
Tumour hypoxia promotes poor patient outcomes, with particularly strong evidence for head and neck squamous cell carcinoma (HNSCC). To effectively target hypoxia, therapies require selection biomarkers and preclinical models that can accurately model
Externí odkaz:
https://doaj.org/article/8463ca23a4994262a7d8bf8b809ac374
Autor:
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John J. Nemunaitis, Dennis Kee, Avik Shome, Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar A. Grénman, Laura Caporiccio, Trevor D. McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan K. Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin G. Print, William R. Wilson, Michael A. Curran, Francis W. Hunter
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/b8265d5c0ed44e2583f6823d2b9a7cc0
Autor:
Mandana Hunter, Krista J. Spiller, Myrna A. Dominique, Hong Xu, Francis W. Hunter, Terry C. Fang, Rebecca G. Canter, Christopher J. Roberts, Richard M. Ransohoff, John Q. Trojanowski, Virginia M.-Y. Lee
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract The microglial reaction is a hallmark of neurodegenerative conditions, and elements thereof may exert differential effects on disease progression, either worsening or ameliorating severity. In amyotrophic lateral sclerosis (ALS), a syndrome
Externí odkaz:
https://doaj.org/article/f1e0fa8cb34c47c4962e39499fbefb6f
Autor:
Julia K. Harms, Tet-Woo Lee, Tao Wang, Amy Lai, Dennis Kee, John M. Chaplin, Nick P. McIvor, Francis W. Hunter, Andrew M. J. Macann, William R. Wilson, Stephen M.F. Jamieson
Publikováno v:
Cells, Vol 8, Iss 7, p 717 (2019)
Tumour hypoxia is a marker of poor prognosis and failure of chemoradiotherapy in head and neck squamous cell carcinoma (HNSCC), providing a strategy for therapeutic intervention in this setting. To evaluate the utility of the hypoxia-activated prodru
Externí odkaz:
https://doaj.org/article/dd7ebfffd5a142ad8a67293e0040e022
Autor:
Jingli Wang, William R. Wilson, Susan M. Pullen, Jiechuang Su, Huai-Ling Hsu, Francis W. Hunter
Supplementary Figures. Supplementary Figures including correlations of HAP sensitivity between cell lines, development and characterisation of doxycycline-inducible shRNA cell lines, and effect of BRCA2 knockout on radiation sensitivity of DLD-1 tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5024b37df1574f0ecb36039cae084bf4
https://doi.org/10.1158/1535-7163.22502809
https://doi.org/10.1158/1535-7163.22502809
Autor:
Jingli Wang, William R. Wilson, Susan M. Pullen, Jiechuang Su, Huai-Ling Hsu, Francis W. Hunter
Supplementary Tables. Supplementary Tables (including statistical analysis of relationships between one-electron reductase activity, HR status and chemosensitivity) and supplementary references related to this material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b74e544cf3021c52e6a78e33361d5e
https://doi.org/10.1158/1535-7163.22502806.v1
https://doi.org/10.1158/1535-7163.22502806.v1
Autor:
Bradly G. Wouters, William R. Wilson, Danny Rischin, Benjamin Solomon, Marianne Koritzinsky, Kevin R. Brown, Troy Ketela, Jason Moffat, David P. Goldstein, Ilan Weinreb, Sreevalsan Sreebhavan, Naveen Joshi, Yongchuan Gu, Jingli Wang, Ravi N. Vellanki, Zvi Shalev, Richard J. Young, Francis W. Hunter
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb3693755b3b6383777f198719fb120
https://doi.org/10.1158/0008-5472.22407413.v1
https://doi.org/10.1158/0008-5472.22407413.v1
Autor:
Bradly G. Wouters, William R. Wilson, Danny Rischin, Benjamin Solomon, Marianne Koritzinsky, Kevin R. Brown, Troy Ketela, Jason Moffat, David P. Goldstein, Ilan Weinreb, Sreevalsan Sreebhavan, Naveen Joshi, Yongchuan Gu, Jingli Wang, Ravi N. Vellanki, Zvi Shalev, Richard J. Young, Francis W. Hunter
List of shRNAs on the custom reductase library.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cf27262fac1b235fd4f9be54d70a47
https://doi.org/10.1158/0008-5472.22407401.v1
https://doi.org/10.1158/0008-5472.22407401.v1
Autor:
Bradly G. Wouters, William R. Wilson, Danny Rischin, Benjamin Solomon, Marianne Koritzinsky, Kevin R. Brown, Troy Ketela, Jason Moffat, David P. Goldstein, Ilan Weinreb, Sreevalsan Sreebhavan, Naveen Joshi, Yongchuan Gu, Jingli Wang, Ravi N. Vellanki, Zvi Shalev, Richard J. Young, Francis W. Hunter
Supplementary Figure Legends from Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f38a91752879e9299b8e37157291df
https://doi.org/10.1158/0008-5472.22407422.v1
https://doi.org/10.1158/0008-5472.22407422.v1
Autor:
Bradly G. Wouters, William R. Wilson, Danny Rischin, Benjamin Solomon, Marianne Koritzinsky, Kevin R. Brown, Troy Ketela, Jason Moffat, David P. Goldstein, Ilan Weinreb, Sreevalsan Sreebhavan, Naveen Joshi, Yongchuan Gu, Jingli Wang, Ravi N. Vellanki, Zvi Shalev, Richard J. Young, Francis W. Hunter
Evaluation of SN30000-induced bystander cell killing in a co-culture system (S1); SN30000 clonogenic survival curves for HT-29, PANC-1 cells and HKO1 (S2); Plating efficiency in HT-29, PANC-1 and HKO2 reductase screens (S3); Density distributions and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c99dff7b53b32a8b33ad93fbfbfaf99
https://doi.org/10.1158/0008-5472.22407416
https://doi.org/10.1158/0008-5472.22407416