Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Francis V. DeFeudis"'
Autor:
Francis V. DeFeudis, Katy Drieu
Publikováno v:
Drug Development Research. 62:1-25
This overview is focused on the stress-alleviating and vigilance-enhancing properties of Ginkgo biloba extract (EGb 761) that have been observed in animal models and in humans and that appear useful in explaining the therapeutic effects of the extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e919ff7a694d5743cd2c7d9472eeb01
https://doi.org/10.1002/ddr.10351
https://doi.org/10.1002/ddr.10351
Publikováno v:
Fundamental and Clinical Pharmacology. 17:405-417
Recent studies conducted with various molecular, cellular and whole animal models have revealed that leaf extracts of Ginkgo biloba may have anticancer (chemopreventive) properties that are related to their antioxidant, anti-angiogenic and gene-regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0216f098b86229d85ef899fdc673a56
https://doi.org/10.1046/j.1472-8206.2003.00156.x
https://doi.org/10.1046/j.1472-8206.2003.00156.x
Autor:
Francis V. DeFeudis
Publikováno v:
Drug Development Research. 57:214-235
Ginkgo biloba leaf extract (EGb 761), which contains many constituents, including flavonoid glycosides and terpenoids (ginkgolides, bilobalide), is used to treat cerebrovascular and peripheral vascular insufficiency, as well as cognitive impairment a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd8468754c0a21f8686ab872791aac4
https://doi.org/10.1002/ddr.10151
https://doi.org/10.1002/ddr.10151
Autor:
Francis V Defeudis
Publikováno v:
Pharmacological Research. 46:565-568
In vivo studies have indicated that systemically administered bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba leaf extracts, can reduce cerebral edema produced by triethyltin, decrease cortical infarct volume in certain stroke mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c399cf424034854f2a906b841b1a308d
https://doi.org/10.1016/s1043-6618(02)00233-5
https://doi.org/10.1016/s1043-6618(02)00233-5
Publikováno v:
Pharmacology Biochemistry and Behavior. 56:333-339
The social interaction test was used to examine the effects of an extract of Ginkgo biloba (EGb 761) and its possible interactions with diazepam and ethyl beta-carboline-3-carboxylate (beta-CCE). Pairs of naive (unfamiliar) male Wistar AF rats subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6874a4da5aa77193ad7859b4952447fb
https://doi.org/10.1016/s0091-3057(96)00298-5
https://doi.org/10.1016/s0091-3057(96)00298-5
Publikováno v:
General Pharmacology: The Vascular System. 25:1009-1016
1. Young (4-month-old) and old (20-month-old) rats, maintained under water restriction, were trained to discriminate to obtain a small amount of drinking water as a reward. Each animal had to learn to press a lever corresponding to a light that was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f28fb2431c269a1344c604371c8baf3
https://doi.org/10.1016/0306-3623(94)90111-2
https://doi.org/10.1016/0306-3623(94)90111-2
Publikováno v:
Drug Development Research. 32:29-41
Ventricular myocytes of guinea pig heart were used to examine the effects of an extract of Ginkgo biolba (EGb 761) on the action potential and individual transmembrane ionic currents. Elecrophysiological events were recorded using the “whole-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4cfae83cc01edf27a8c674cc636a629
https://doi.org/10.1002/ddr.430320106
https://doi.org/10.1002/ddr.430320106
Publikováno v:
Drug Development Research. 31:164-169
The metabolic action of an extract of Ginkgo biloba (EGb 761) has been examined in an ex vivo study of rat erythrocytes. Oral administration of EGb 761 (100 mg/kg/day) for 5 days to Wistar rats caused an increase in the in vitro uptake of glucose by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04acd90685f12a41a85efbea9c14f181
https://doi.org/10.1002/ddr.430310303
https://doi.org/10.1002/ddr.430310303
Publikováno v:
General Pharmacology: The Vascular System. 25:31-46
1. 1. The effects of repeated (5-day) treatments with an extract of Ginkgo biloba leaves (EGb 761), bilobalide, and ginkgolide B on the in vitro electrical activity of insulin-secreting pancreatic β cells of mice have been examined using intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e565bb39f2d3f73e7434e0803ba15032
https://doi.org/10.1016/0306-3623(94)90007-8
https://doi.org/10.1016/0306-3623(94)90007-8
Autor:
Ewald, Pretner, Hakima, Amri, Wenping, Li, Rachel, Brown, Chin-Shoou, Lin, Erini, Makariou, Francis V, Defeudis, Katy, Drieu, Vassilios, Papadopoulos
Publikováno v:
Anticancer research. 26(1A)
The peripheral-type benzodiazepine receptor (PBR) is an 18-kDa high affinity drug- and cholesterol-binding protein that is involved in various cell functions, including cell proliferation and apoptosis. PBR was shown to be overexpressed in certain ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3b8e31885ebca4d59e6ec9132c2c82d
https://pubmed.ncbi.nlm.nih.gov/16475673
https://pubmed.ncbi.nlm.nih.gov/16475673