Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Francis T. Danehy"'
Autor:
Nicole Danek, Ashish Kalra, Stefan Wawersik, Ryan R. Faucette, Gregory J. Carven, Constance Martin, Alan Buckler, Anastasia Nikiforov, Frederick C. Streich, Christopher Brueckner, Pichai Raman, Lin Susan, Kevin B. Dagbay, Christopher Littlefield, Justin W. Jackson, Christopher Chapron, Francis T. Danehy, Thomas Schurpf, Christopher Boston, Allison Simpson, Abhishek Datta, Capili Allan
Publikováno v:
Science Translational Medicine. 12
Despite breakthroughs achieved with cancer checkpoint blockade therapy (CBT), many patients do not respond to anti-programmed cell death-1 (PD-1) due to primary or acquired resistance. Human tumor profiling and preclinical studies in tumor models hav
Autor:
Christopher Littlefield, Ashish Kalra, Anastasia Nikiforov, Christopher Boston, Allison Simpson, Constance Martin, Stefan Wawersik, Abhishek Datta, Christopher Chapron, Francis T. Danehy, Thomas Schurpf, Gregory J. Carven, Lin Susan, Justin W. Jackson, Alan Buckler
Publikováno v:
Cancer Research. 79:4090-4090
Despite the clinical breakthroughs achieved by checkpoint blockade therapy (CBT), a majority of patients treated with PD-(L)1 inhibitors fail to respond due to primary or acquired resistance. TGFβ signaling has recently been implicated as a mechanis
Publikováno v:
Antiviral research. 85(3)
Nucleoside analogs are effective inhibitors of the hepatitis C virus (HCV) in the clinical setting. One such molecule, 2'-C-methyl-cytidine (2'-MeC), entered clinical development as NM283, a valine ester prodrug form of 2'-MeC possessing improved ora
Publikováno v:
Molecular and Cellular Endocrinology. 80:75-82
Insulin-like growth factor-II (IGF-II) is postulated to have autocrine and/or paracrine functions in developing fetal tissues, but has never been reported in human fetal reproductive organs. The forms of IGF-II found in normal human serum include a 6
Autor:
Mark A. Marchionni, Francis T. Danehy, Maio Su Chen, Olivia Bermingham-McDonogh, Joy Lucas, David I. Gwynne, Steven S. Scherer, Colleen Nolan
Publikováno v:
The Journal of comparative neurology. 349(3)
The distribution of neuregulin transcripts in rat brains was studied by both RNA blotting and in situ hybridization. Our data demonstrate that multiple neuregulin transcripts are expressed in neurons of the basal forebrain, the hippocampus, the dienc