Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Francis Stewart A"'
Autor:
Wentao Zheng, Yuxuan Wang, Jie Cui, Guangyao Guo, Yufeng Li, Jin Hou, Qiang Tu, Yulong Yin, Francis Stewart, Youming Zhang, Xiaoying Bian, Xue Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The complexities encountered in microbial metabolic engineering continue to elude prediction and design. Unravelling these complexities requires strategies that go beyond conventional genetics. Using multiplex mutagenesis with double strande
Externí odkaz:
https://doaj.org/article/0c3dd09046824c6bbc240b86aaad55c2
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 80, Iss 1, Pp e1-e10 (2024)
Two conceptual strands of research within the field of cathedral studies have theorised the capacity of Anglican cathedrals to engage more successfully than parish churches with the wider non-churchgoing community. One strand has explored mobilising
Externí odkaz:
https://doaj.org/article/2b8bde5c79f44687b9bf63a15c3bf947
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 80, Iss 1, Pp e1-e9 (2024)
Rooted in the field of cathedral studies, this paper draws into dialogue three bodies of knowledge: Edward Bailey’s notion of implicit religion that, among other things, highlights the continuing traction of the Christian tradition and Christian pr
Externí odkaz:
https://doaj.org/article/9fa6c4a5d32f4a49a4ba1423384cc19a
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-4 (2023)
Recent structures of DNA-bound bacterial and phage recombinases provide insights into homologous recombination and suggest relation to the eukaryotic Rad52 and identification of a Rad52 single strand annealing protein (SSAP) superfamily.
Externí odkaz:
https://doaj.org/article/87df98d886db484a95c25a6409de8c07
Publikováno v:
HTS Teologiese Studies/Theological Studies, Vol 78, Iss 4, Pp e1-e11 (2022)
High profile (and controversial) events and installations, like the Helter-Skelter in Norwich and the Crazy Golf Bridges in Rochester, have drawn attention to innovation and public engagement within Anglican cathedrals. The present study contextualis
Externí odkaz:
https://doaj.org/article/584b779abff3420696c8bbe3da3407d2
Autor:
Laura Medina-Ruiz, Robin Bartolini, Gillian J Wilson, Douglas P Dyer, Francesca Vidler, Catherine E Hughes, Fabian Schuette, Samantha Love, Marieke Pingen, Alan James Hayes, Jun Fu, Adrian Francis Stewart, Gerard J Graham
Publikováno v:
eLife, Vol 11 (2022)
Inflammatory chemokines and their receptors are central to the development of inflammatory/immune pathologies. The apparent complexity of this system, coupled with lack of appropriate in vivo models, has limited our understanding of how chemokines or
Externí odkaz:
https://doaj.org/article/839541cdc7394dd999c38fba35396645
Autor:
Johanna Grinat, Julian Heuberger, Ramon Oliveira Vidal, Neha Goveas, Frauke Kosel, Antoni Berenguer-Llergo, Andrea Kranz, Annika Wulf-Goldenberg, Diana Behrens, Bálint Melcher, Sascha Sauer, Michael Vieth, Eduard Batlle, A. Francis Stewart, Walter Birchmeier
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Intestinal cancer stem cells (CSC) are associated with colon cancer. Here, the authors show that Wnt/beta-catenin signalling in CSC requires the epigenetic regulator Mll1 to promote stemness and tumourigenesis in murine and human colon cancer models.
Externí odkaz:
https://doaj.org/article/3b5f2ff3d1124d7c81f483c2f20a5a38
Autor:
Neha Goveas, Claudia Waskow, Kathrin Arndt, Julian Heuberger, Qinyu Zhang, Dimitra Alexopoulou, Andreas Dahl, Walter Birchmeier, Konstantinos Anastassiadis, A Francis Stewart, Andrea Kranz
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009250 (2021)
Epigenetic mechanisms are gatekeepers for the gene expression patterns that establish and maintain cellular identity in mammalian development, stem cells and adult homeostasis. Amongst many epigenetic marks, methylation of histone 3 lysine 4 (H3K4) i
Externí odkaz:
https://doaj.org/article/4875509f143d4a909776991e391ae158
Autor:
Gregory C. Addicks, Caroline E. Brun, Marie-Claude Sincennes, John Saber, Christopher J. Porter, A. Francis Stewart, Patricia Ernst, Michael A. Rudnicki
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
PAX7 transcription factor specifies the myogenic identity of muscle stem cells and acts as a nodal factor by stimulating proliferation while inhibiting differentiation. Here authors find that Mll1 deletion in myoblasts in mice results in reduced H3K4
Externí odkaz:
https://doaj.org/article/8f1a223e30424b10ab115c2947e3f185
Autor:
Jia Yin, Wentao Zheng, Yunsheng Gao, Chanjuan Jiang, Hongbo Shi, Xiaotong Diao, Shanshan Li, Hanna Chen, Hailong Wang, Ruijuan Li, Aiying Li, Liqiu Xia, Yulong Yin, A. Francis Stewart, Youming Zhang, Jun Fu
Publikováno v:
iScience, Vol 14, Iss , Pp 1-14 (2019)
Summary: The limited efficiency of the available tools for genetic manipulation of Pseudomonas limits fundamental research and utilization of this genus. We explored the properties of a lambda Red-like operon (BAS) from Pseudomonas aeruginosa phage A
Externí odkaz:
https://doaj.org/article/4db6bdfd7bf64709a017e0b414576b4a