Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Francis R LeBlanc"'
Autor:
Francis R. LeBlanc, Zainul S. Hasanali, August Stuart, Sara Shimko, Kamal Sharma, Violetta V. Leshchenko, Samir Parekh, Haiqing Fu, Ya Zhang, Melvenia M. Martin, Mark Kester, Todd Fox, Jiangang Liao, Thomas P. Loughran, Juanita Evans, Jeffrey J. Pu, Stephen E. Spurgeon, Mirit I. Aladjem, Elliot M. Epner
Publikováno v:
Oncotarget. 13
Classical MCL (cMCL) constitutes 6-8% of all B cell NHL. Despite recent advances, MCL is incurable except with allogeneic stem cell transplant. Blastic mantle cell lymphoma (bMCL) is a rarer subtype of cMCL associated with an aggressive clinical cour
Autor:
David Montani, Marc Humbert, Francis R LeBlanc, Thomas P. Loughran, Amandine Le Bourgeois, Cedric Pastoret, Céline Chabanne, Olivier Decaux, Stéphane Dominique, Thierry Lamy, Brieuc Cherel, Matteo Leoncin, Mohamed Hamidou, François Lifermann, Renato Zambello
Publikováno v:
Chest
Chest, American College of Chest Physicians, 2020, 158 (6), pp.2602-2609. ⟨10.1016/j.chest.2020.07.094⟩
Chest, 2020, 158 (6), pp.2602-2609. ⟨10.1016/j.chest.2020.07.094⟩
Chest, American College of Chest Physicians, 2020, 158 (6), pp.2602-2609. ⟨10.1016/j.chest.2020.07.094⟩
Chest, 2020, 158 (6), pp.2602-2609. ⟨10.1016/j.chest.2020.07.094⟩
International audience; [No abstract available]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b463bc2ac946397343976c963e6daa1f
http://hdl.handle.net/11577/3391853
http://hdl.handle.net/11577/3391853
Publikováno v:
ACG Case Reports Journal
We report a unique case of ulcerative colitis-associated bronchiectasis in a pediatric patient 6 years after colectomy. The patient presented with a chronic cough and had a computed tomography demonstrating bronchiectasis. She was treated with sputum
Autor:
Jun Yang, Thomas L. Olson, Thomas P. Loughran, David J. Feith, Shubha Dighe, Cait E. Hamele, Francis R LeBlanc
Large granular lymphocyte (LGL) leukemia results from clonal expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer (NK) cells. Chronic antigen stimulation is postulated to promote long-term survival of LGL leukemia cells through cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfd80c500df5a8c4449ab7e74b63907
https://europepmc.org/articles/PMC6014359/
https://europepmc.org/articles/PMC6014359/
Autor:
Francis R LeBlanc, Thomas P. Loughran, Jeremy A. Hengst, Jong K. Yun, David J. Feith, Valerie S. Calvert, Emanuel F. Petricoin, Todd E. Fox, Xin Liu
Publikováno v:
Cancer Biology & Therapy. 16:1830-1840
Sphingolipid metabolism has been identified as a potential therapeutic target in cancer. Sphingosine-1-phosphate (S1P) is a potent bioactive sphingolipid metabolite produced by sphingosine kinases-1 and -2 (SPHK1 and SPHK2). Elevated SPHK1 has been f
Autor:
Thomas P. Loughran, Francis R LeBlanc
Publikováno v:
Expert Opinion on Orphan Drugs. 3:859-867
Introduction: Large granular lymphocyte (LGL) leukemia is a rare lymphoproliferative disease of cytotoxic T lymphocytes. It almost always is a chronic, indolent disease; however, rarely it can present with an aggressive clinical course. The lack of a
Autor:
Austin G. Kulasekararaj, Satu Mustjoki, Bartlomiej P Przychodzen, Hanna Rajala, Catherine Nissen, Sonja Lagström, Inés Gómez-Seguí, Dan Zhang, Thomas P. Loughran, Holleh D Husseinzadeh, Andres Jerez, Thomas L. Olson, Aleksandra Wodnar-Filipowicz, Manuel G. Afable, Alan F. List, Michael J. Clemente, Pekka Ellonen, Ghulam J. Mufti, Naoko Hosono, Francis R LeBlanc, Alan E. Lichtin, Hideki Makishima, Kathy L. McGraw, Jaroslaw P. Maciejewski, André Tichelli
Publikováno v:
Blood. 122:2453-2459
Large granular lymphocyte leukemia (LGL) is often associated with immune cytopenias and can cooccur in the context of aplastic anemia (AA) and myelodysplastic syndromes (MDS). We took advantage of the recent description of signal transducer and activ
Publikováno v:
Immunotherapy. 5:231-234
Evaluation of: Mishra A, Liu S, Sams GH et al. Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation. Cancer Cell 22(5), 645–655 (2012). There is increasing evidence i
Autor:
Kathy L. McGraw, Satu Mustjoki, Mikkael A. Sekeres, Hideki Makishima, Thomas L. Olson, Eric D. Hsi, Andres Jerez, Lisa Durkin, Bartlomiej P Przychodzen, Hanna Koskela, Kathryn M Guinta, Marcin W. Wlodarski, Manuel G. Afable, Michael J. Clemente, Kwok Peng Ng, Francis R LeBlanc, Dan Zhang, Thomas P. Loughran, Alan F. List, Jaroslaw P. Maciejewski, Kimmo Porkka, Inés Gómez-Seguí
Publikováno v:
Blood. 120:3048-3057
Chronic lymphoproliferative disorders of natural killer cells (CLPD-NKs) and T-cell large granular lymphocytic leukemias (T-LGLs) are clonal lymphoproliferations arising from either natural killer cells or cytotoxic T lymphocytes (CTLs). We have inve
Publikováno v:
Future Oncology. 8:787-801
Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferative disorder of cytotoxic lymphocytes characterized by an expansion of CD3+ cytotoxic T lymphocytes or CD3- natural killer cells. Patients present with various cytopenias including