Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Francis Poulin"'
Autor:
Francis Poulin
The Gulf Stream plays an important role in the meridional overturning circulation in the North Atlantic, one of the primary mechanism by which the warm, salty water can move from low to high latitudes. It also provides closure to the North Atlantic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fde045cf2f4a7d319cdefe6addd8036
https://doi.org/10.5194/egusphere-egu23-10130
https://doi.org/10.5194/egusphere-egu23-10130
Publikováno v:
Physics of Fluids. 34:084102
This paper uses a linear stability analysis to investigate instabilities of barotropic and baroclinic jets that satisfy the necessary condition for inerital instabilities within the context of a rotating, stratified Boussinesq model. First, we review
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8040beb4247134149a773184424a08ef
https://doi.org/10.1063/5.0100979
https://doi.org/10.1063/5.0100979
Autor:
Yuxia Luo, Eric Pastor, Bruce Sol, John M. Martin, Karen A. Vincent, Michelle Joubert, Amy Frederick, Samuel C. Wadsworth, Donna Armentano, Robert B. Jackson, Francis Poulin
Publikováno v:
Human Gene Therapy Methods. 24:253-269
Adeno-associated virus (AAV) producer cell lines represent an effective method for large-scale production of AAV vectors. We set out to evaluate and characterize the use of an abbreviated protocol to generate "masterwells" (MWs; a nonclonal cell popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f007eac4c33f141f41ff6dd5c08a21
https://doi.org/10.1089/hgtb.2013.046
https://doi.org/10.1089/hgtb.2013.046
Autor:
Francis Poulin, Victor R. Cairns, Jin Zhang, Jose Sancho, Christine Demaria, Juanita Campos-Rivera, Scott Estes, Ping Liu, Kenneth P. Karey
Publikováno v:
Biotechnology and Bioengineering. 108:2611-2622
Here we describe a method that couples flow cytometric detection with the attenuated translation of a reporter protein to enable efficient selection of CHO clones producing high levels of recombinant proteins. In this system, a small cell surface rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699975d522d4ef3714aef515ac53a848
https://doi.org/10.1002/bit.23219
https://doi.org/10.1002/bit.23219
Publikováno v:
Genomics. 95(5):261-267
Bacterial artificial chromosomes (BACs) are capable of propagating large fragments of DNA and have become an invaluable tool for studying genome biology. To fill a phylogenetic gap in available genomic sequence and to complement ongoing molecular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa280ba819ccd2c3e68bf59098ce6f0
Autor:
Denis Richard, Sabina Paglialunga, Olivier Le Bacquer, Katherine Cianflone, Francis Poulin, Emmanuel Petroulakis, Nahum Sonenberg
Publikováno v:
Journal of Clinical Investigation. 117:387-396
The most common pathology associated with obesity is insulin resistance, which results in the onset of type 2 diabetes mellitus. Several studies have implicated the mammalian target of rapamycin (mTOR) signaling pathway in obesity. Eukaryotic transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f66d4a1aec369894e7fcf7a59a5e934
https://doi.org/10.1172/jci29528
https://doi.org/10.1172/jci29528
Autor:
Malak Shoukry, Francis Poulin, Olivier Couronne, Len A. Pennacchio, Shyam Prabhakar, Veena Afzal, Edward M. Rubin
Publikováno v:
Prabhakar, Shyam; Poulin, Francis; Shoukry, Malak; Afzal, Veena; Rubin, Edward M.; Couronne, Olivier; et al.(2005). Close Sequence Comparisons are Sufficient to Identify Human cis-Regulatory Elements. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/0zj6n800
Cross-species DNA sequence comparison is the primary method used to identify functional noncoding elements in human and other large genomes. However, little is known about the relative merits of evolutionarily close and distant sequence comparisons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0250bb737e98efe3deda26b60ea21bc
https://doi.org/10.1101/gr.4717506
https://doi.org/10.1101/gr.4717506
Publikováno v:
Structure. 14:913-923
Summary The X-ray structure of the C-terminal region of human eukaryotic translation initiation factor 4G (eIF4G) has been determined at 2.2 A resolution, revealing two atypical HEAT-repeat domains. eIF4G recruits various translation factors and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd990d38c643731b0331079578693901
https://doi.org/10.1016/j.str.2006.03.012
https://doi.org/10.1016/j.str.2006.03.012
Autor:
Amy Holt, Francis Poulin, Ingrid Plajzer-Frick, Len A. Pennacchio, Marcelo A. Nobrega, Veena Afzal, Edward M. Rubin
Publikováno v:
Genomics. 85:774-781
Genomic sequence comparisons among human, mouse, and pufferfish (Takifugu rubripes (Fugu)) have revealed a set of extremely conserved noncoding sequences. While this high degree of sequence conservation suggests severe evolutionary constraint and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6bd109f8e8b14d1b665ced2405b9ef
https://doi.org/10.1016/j.ygeno.2005.03.003
https://doi.org/10.1016/j.ygeno.2005.03.003
Publikováno v:
Journal of Biological Chemistry. 273:14002-14007
Translation initiation in eukaryotes is mediated by the cap structure (m7GpppN, where N is any nucleotide) present at the 5' end of all cellular mRNAs, except organellar. The cap is recognized by eukaryotic initiation factor 4F (eIF4F), which consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dada63e1cb6004b0496741a3c0831cec
https://doi.org/10.1074/jbc.273.22.14002
https://doi.org/10.1074/jbc.273.22.14002