Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Francis Pancic"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 15:813-819
Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washi
Publikováno v:
Journal of Medicinal Chemistry. 27:691-694
Several keto phosphonates, phosphonoacetates , and dialkyl phosphonates containing (aryloxy)aryl groups were synthesized and evaluated for antiherpteic activity. Two of the most active compounds, 12 and 16, were evaluated topically in the mouse vagin
Autor:
Francis Pancic, Guy D. Diana
Publikováno v:
Angewandte Chemie International Edition in English. 15:410-416
The purpose of this review is to provide an overview of current screening methodology and major advances in the area of viral chemotherapy. This presentation will be limited to those drugs which are currently in use and those which having shown activ
Autor:
Francis Pancic, Guy D. Diana
Publikováno v:
Angewandte Chemie. 88:458-465
In diesem Aufsatz soll nach der Beschreibung der von uns verwendeten Screening-Methode ein Uberblick uber die wichtigsten Fortschritte auf dem Gebiet der viralen Chemotherapie gegeben werden. Die Darstellung wird sich auf Arzneimittel beschranken, di
Publikováno v:
Journal of Medicinal Chemistry. 16:1050-1053
Autor:
Guy D. Diana, U. Joseph Salvador, Ethel S. Zalay, Philip M. Carabateas, Gordon L. Williams, Joseph C. Collins, Francis Pancic
Publikováno v:
Journal of medicinal chemistry. 20(6)
A series of aryloxy alkyl diketones II was synthesized and screened in vitro for antiviral activity. The effect of various substituents on the phenyl ring, as well as the length of the alkyl bridge, was examined to establish the requirements for opti
Autor:
Gordon L. Williams, U. Joseph Salvador, E. S. Zalay, Joseph C. Collins, Francis Pancic, B. A. Steinberg, Guy D. Diana, Philip M. Carabateas
Publikováno v:
Journal of medicinal chemistry. 21(7)
A series of bis(beta-diketones) was synthesized and tested in vitro for antiviral actitity against herpes simplex type 2. Two parameters which were studied in an effort to optimize activity were the nature of the aryl group and the length of the alky
Autor:
U. J. Salvador, G. L. Williams, Guy D. Diana, Philip M. Carabateas, Francis Pancic, J. C. Collins, E. S. Zalay
Publikováno v:
Chemischer Informationsdienst. 8
Publikováno v:
Chemischer Informationsdienst. 15
Several keto phosphonates, phosphonoacetates , and dialkyl phosphonates containing (aryloxy)aryl groups were synthesized and evaluated for antiherpteic activity. Two of the most active compounds, 12 and 16, were evaluated topically in the mouse vagin
Publikováno v:
Chemischer Informationsdienst. 4