Zobrazeno 1 - 10 of 63 pro vyhledávání: '"Francis P. Tally"'
1
Daptomycin: a lipopeptide antibiotic for the treatment of serious Gram-positive infections
Autor: Grace M. Thorne, Judith N. Steenbergen, Jeff Alder, Francis P. Tally
Publikováno v: Journal of Antimicrobial Chemotherapy. 55:283-288
Infections caused by drug-resistant pathogens are on the rise. Daptomycin, a cyclic lipopeptide with activity against most Gram-positive pathogens, including vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus, is a newly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7640ace85683a6d385417434ad6519ae
https://doi.org/10.1093/jac/dkh546
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2
Daptomycin Versus Ciprofloxacin in the Treatment of Complicated Urinary Tract Infection Due to Gram-positive Bacteria
Autor: Barry I. Eisenstein, Francis P. Tally, Kurt G. Naber
Publikováno v: Infectious Diseases in Clinical Practice. 12:322-327
Background:Complicated urinary tract infections (UTIs) due to Gram-positive pathogens are of increasing concern because of steadily emerging resistance to standard antibiotic therapy. Daptomycin is the first available agent of a new class of antibiot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e3e95756694bf74dc4f387aed9fb916
https://doi.org/10.1097/01.idc.0000144898.12957.eb
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3
The Importance of Bactericidal Drugs: Future Directions in Infectious Disease
Autor: Francis P. Tally, Kenneth V. I. Rolston, Manjari Joshi, George A. Pankey, Robert W. Finberg, Michael West, E. Patchen Dellinger, William A. Craig, Peter K. Linden, Michael J. Rybak, John C. Rotschafer, Robert C. Moellering
Publikováno v: Clinical Infectious Diseases. 39:1314-1320
Background. Although a considerable amount of research has gone into the study of the role of bactericidal versus bacteriostatic antimicrobial agents in the treatment of different infectious diseases, there is no accepted standard of practice. Method
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dc5a0f00a5436c5bba43f7623523e4
https://doi.org/10.1086/425009
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5
Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems
Autor: William J. Weiss, Subas M. Sakya, Nilda V. Jacobus, Francis P. Tally, Karen Bush, Panayota Bitha, Lin Yang I, Stanley A. Lang, Strohmeyer Timothy W, Peter Petersen, Niraja Bhachech, Youjun Yang, Li Zhong, Testa Raymond T, Ving J. Lee
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:1671-1676
A series of twelve highly active aminomethyl-THF 1β-methylcarbapenems 3a-1 were synthesized. Of these, carbapenems 3a-f demonstrated a spectrum of antimicrobial activity comparable to those of imipenem and meropenem with the exception of only modera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e7cf0fda2095464b1f1974109e04d23
https://doi.org/10.1016/s0960-894x(97)00282-5
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7
Daptomycin: a novel agent for Gram-positive infections
Autor: Francis P. Tally, Claudio Carini, Michael L Zeckel, Frederick B. Oleson, Cindy L Berman, Margaret M Wasilewski, George L Drusano
Publikováno v: Expert opinion on investigational drugs. 8(8)
The alarming increase in the incidence of Gram-positive infections, including those caused by resistant bacteria, has sparked renewed interest in novel antibiotics. One such agent is daptomycin, a novel lipopeptide antibiotic with proven bactericidal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5195e56c69c37e8d57696afa40d2c64
https://pubmed.ncbi.nlm.nih.gov/15992147
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8
The safety and efficacy of daptomycin for the treatment of complicated skin and skin-structure infections
Autor: Edward Campanaro, Barry I. Eisenstein, Francis P. Tally, Dennis G. Maki, Investigators, Robert D. Arbeit
Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 38(12)
Daptomycin is the first available agent from a new class of antibiotics, the cyclic lipopeptides, that has activity against a broad range of gram-positive pathogens, including organisms that are resistant to methicillin, vancomycin, and other current
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dcef801b3e5add2af89bd0f34e355e
https://pubmed.ncbi.nlm.nih.gov/15227611
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9
Once-Daily Dosing in Dogs Optimizes Daptomycin Safety
Autor: J. B. Kirkpatrick, K. S. Regan, Frederick B. Oleson, J.-J. Lai, C. L. Berman, Francis P. Tally
Daptomycin is a novel lipopeptide antibiotic with potent bactericidal activity against most clinically important gram-positive bacteria, including resistant strains. Daptomycin has been shown to have an effect on skeletal muscle. To guide the clinica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae43db82642a521b5d0a8edb1dffcbe
https://europepmc.org/articles/PMC101585/
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10
Drug target validation: lethal infection blocked by inducible peptide
Autor: Megan King, Francis P. Tally, Tongchuan Li, Jianshi Tao, Gene Connelly, Jared Silverman, Jiansu Zhang, Paul Schimmel, Audrey Lim, Philip Wendler
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 97(2)
Genome projects are generating large numbers of potential new targets for drug discovery. One challenge is target validation, proving the usefulness of a specific target in an animal model. In this paper, we demonstrate a new approach to validation a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d21bad15499da32a9f84c5520882ffc
https://pubmed.ncbi.nlm.nih.gov/10639157
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