Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Francis P. Gasparro"'
Autor:
Harold Walder, Diane Renee Fels, Wayne F. Beyer, Katherine S. Hansen, Alexandru D. Buhimschi, Francis P. Gasparro, Hongwu Jing, David M. Gooden, Mark W. Dewhirst
Publikováno v:
Photochemistry and photobiology, vol 96, iss 5
Photochem Photobiol
Photochem Photobiol
Psoralen is a furocoumarin natural product that intercalates within DNA and forms covalent adducts when activated by ultraviolet radiation. It is well known that this property contributes to psoralen's clinical efficacy in several disease contexts, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afcf67789fff01d171ee95aff1a133f
https://escholarship.org/uc/item/7tk517vc
https://escholarship.org/uc/item/7tk517vc
Autor:
Francis P. Gasparro
In one form or another psoralens have been in use dating back to biblical times for the treatment of depigmented patches of skin. However, it has only been in the past 40 years that the structure and function of psoralens have been elucidated. Althou
Publikováno v:
Photochemistry and Photobiology. 90:241-246
UVA-activated psoralens are used to treat hyperproliferative skin conditions due to their ability to form DNA photoadducts, which impair cellular processes and may lead to cell death. Although UVA (320-400 nm) is more commonly used clinically, studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eca1b43f8e571df0d1449c8b7f497a7
https://doi.org/10.1111/php.12171
https://doi.org/10.1111/php.12171
Autor:
Francis P. Gasparro
Sunscreens are universally recommended by dermatologists not only to prevent the immediate effects of overexposure to sunlight but also to prevent skin cancer. While the former goal is immediately evident, the latter remains an unproven hypothesis an
Autor:
Francis P. Gasparro, Douglas B. Brown, Jouni Uitto, Moetaz El-Domyati, Sameh K. Attia, D. E. Birk, Fatma Y Saleh, Hesham M. Ahmad
Publikováno v:
Experimental Dermatology. 11:398-405
Cutaneous aging is a complex biological phenomenon affecting the different constituents of the skin. To compare the effects of intrinsic and extrinsic aging processes, a total of 83 biopsies were collected from sun-exposed and protected skin of healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de838ffde9d192961d173afd26176a84
https://doi.org/10.1034/j.1600-0625.2002.110502.x
https://doi.org/10.1034/j.1600-0625.2002.110502.x
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 17:126-129
Background: Fluorescent sunlamps are a common source of ultraviolet radiation (UVR) for photobiology research. However, these lamps emit a significant amount of biologically irrelevant wavelengths that, if not removed, can drastically skew results an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b21141eaec197993e3136032f5ffe422
https://doi.org/10.1034/j.1600-0781.2001.170304.x
https://doi.org/10.1034/j.1600-0781.2001.170304.x
Autor:
Eric F. Bernstein, Francis P. Gasparro, Sung K. Kong, Douglas B. Brown, Tsunemichi Takeuchi, Jouni Uitto, B. C. Kwak
Publikováno v:
Experimental Dermatology. 10:55-61
The generation of reactive oxygen species is among the various mechanisms by which ultraviolet radiation damages skin. Tempol, a superoxide dismutase analogue which readily penetrates cell membranes when administered exogenously, has been shown to pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea972425c7682388b10ee339e2d4a92
https://doi.org/10.1034/j.1600-0625.2001.100107.x
https://doi.org/10.1034/j.1600-0625.2001.100107.x
Autor:
Adam E. Peritz, Jouni Uitto, Stephanie Chiarello, Francis P. Gasparro, Douglas B. Brown, David L. Mitchell
Publikováno v:
Photochemistry and Photobiology. 72:340-344
Fluorescent sunlamps are commonly employed as convenient sources in photobiology experiments. The ability of Kodacel to filter photobiologically irrelevant UVC wavelengths has been described. Yet there still remains a major unaddressed issue--the ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e260e20226ce9d3a9211332bfaf228
https://doi.org/10.1562/0031-8655(2000)0720340cfsaai2.0.co2
https://doi.org/10.1562/0031-8655(2000)0720340cfsaai2.0.co2
Autor:
Francis P. Gasparro
Publikováno v:
Environmental Health Perspectives
Sunscreens are ultraviolet radiation (UVR)-absorbing chemicals that attenuate the amount and nature of UVR reaching viable cells in the skin. They are selected and tested for their ability to prevent erythema. No sunscreen prevents photodamage, as it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93590dc175ca8e3a969f3245319bcf73
http://europepmc.org/articles/PMC1637776
http://europepmc.org/articles/PMC1637776