Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Francis M Ndungu"'
Autor:
Robert M Mugo, Sebastian Rausch, Zaneta D Musimbi, Christina Strube, Marie-Kristin Raulf, Olfert Landt, Paul M Gichuki, Friederike Ebner, Jedidah Mwacharo, Maurice R Odiere, Francis M Ndungu, Doris W Njomo, Susanne Hartmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 6, p e0012279 (2024)
BackgroundThe standard diagnosis of Ascaris lumbricoides and other soil-transmitted helminth (STH) infections relies on the detection of worm eggs by copromicroscopy. However, this method is dependent on worm patency and shows only limited accuracy i
Externí odkaz:
https://doaj.org/article/91077f3cc8424017a2d291e150ef0f27
Autor:
Robert M Mugo, Benedict Orindi, Faiz M Shee, Duncan Bellamy, Jedidah Mwacharo, Katie J Ewer, Philip Bejon, Francis M Ndungu
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286117 (2023)
BackgroundRTS,S/AS01 induced anti-circumsporozoite protein (CSP) IgG antibodies are associated with the vaccine efficacy. There is currently no international standardisation of the assays used in the measurement of anti-CSP IgG antibody concentration
Externí odkaz:
https://doaj.org/article/f791229208084c22b81f445ab3ddbd66
Autor:
Eleonora Vianello, PhD, Patricia Gonzalez-Dias, MSc, Suzanne van Veen, BSc, Carmen G Engele, BSc, Edwin Quinten, BSc, Thomas P Monath, MD, Donata Medaglini, ProfPhD, Francesco Santoro, PhD, Angela Huttner, MD, Sheri Dubey, PhD, Michael Eichberg, PhD, Francis M Ndungu, PhD, Peter G Kremsner, ProfMD, Paulin N Essone, PhD, Selidji Todagbe Agnandji, MD, Claire-Anne Siegrist, ProfMD, Helder I Nakaya, PhD, Tom H M Ottenhoff, ProfMD, Mariëlle C Haks, PhD, Selidij T Agnandij, Rafi Ahmed, Jenna Anderson, Floriane Auderset, Philip Bejon, Luisa Borgianni, Jessica Brosnahan, Annalisa Ciabattini, Olivier Engler, Mariëlle C Haks, Ali M Harandi, Donald G Heppner, Alice Gerlini, Angela Huttner, Peter G Kremsner, Donata Medaglini, Thomas P Monath, Francis M Ndungu, Patricia Njuguna, Tom H M Ottenhoff, David Pejoski, Mark Page, Gianni Pozzi, Francesco Santoro, Claire-Anne Siegrist, Sheri Dubey, Michael Eichberg, Essone P Ndong, Kabwende Lumeka, Helder I Nakaya, Patricia Gonzales Dias Carvalho, Sylvia Rothenberger, Eleonora Vianello, Sravya S Nakka, Suzanne van Veen
Publikováno v:
The Lancet Microbe, Vol 3, Iss 2, Pp e113-e123 (2022)
Summary: Background: A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to ident
Externí odkaz:
https://doaj.org/article/9d0108ac7efd4b3a99b85d9af9182e4b
Autor:
Ally Olotu, Frederic Clement, Erik Jongert, Johan Vekemans, Patricia Njuguna, Francis M Ndungu, Kevin Marsh, Geert Leroux-Roels, Philip Bejon
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115126 (2014)
The nature of protective immune responses elicited by immunization with the candidate malaria vaccine RTS,S is still incompletely understood. Antibody levels correlate with protection against malaria infection, but considerable variation in outcome i
Externí odkaz:
https://doaj.org/article/275b52386e7f458c80c1b6ea70df6179
Autor:
Francis M Ndungu, Jedidah Mwacharo, Domtila Kimani, Oscar Kai, Philippe Moris, Erik Jongert, Johan Vekemans, Ally Olotu, Philip Bejon
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52870 (2012)
The candidate malaria vaccine RTS,S/AS01(E) provides significant but partial protection from clinical malaria. On in vitro circumsporozoite protein (CSP) peptide stimulation and intra-cellular cytokine staining of whole blood taken from 407 5-17 mont
Externí odkaz:
https://doaj.org/article/d4d14fae23c945c3b3f5c32a1b4ed52e
Autor:
Frances Ibison, Ally Olotu, Daniel M Muema, Jedida Mwacharo, Eric Ohuma, Domtila Kimani, Kevin Marsh, Philip Bejon, Francis M Ndungu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52939 (2012)
BACKGROUND:Although antibodies are critical for immunity to malaria, their functional attributes that determine protection remain unclear. We tested for associations between antibody avidities to Plasmodium falciparum (Pf) antigens and age, asymptoma
Externí odkaz:
https://doaj.org/article/3c67613d954b4caa827ac25978bbf84b
Autor:
Eunice W Nduati, Dorothy H L Ng, Francis M Ndungu, Peter Gardner, Britta C Urban, Jean Langhorne
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15007 (2010)
B cell and plasma cell responses take place in lymphoid organs, but because of the inaccessibility of these organs, analyses of human responses are largely performed using peripheral blood mononuclear cells (PBMC). To determine whether PBMC are a use
Externí odkaz:
https://doaj.org/article/143aaeb22dfe4ede9679c0b03e9fdc77
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Malaria is caused by apicomplexan parasites of the genus Plasmodium. While infection continues to pose a risk for the majority of the global population, the burden of disease mainly resides in Sub-Saharan Africa. Although immunity develops against di
Externí odkaz:
https://doaj.org/article/fa689ace3696499499ac9830b9c00484
Autor:
John Kimotho, Yiakon Sein, Shahin Sayed, Reena Shah, Kennedy Mwai, Mansoor Saleh, Perpetual Wanjiku, Jedidah Mwacharo, James Nyagwange, Henry Karanja, Bernadette Kutima, John Gitonga, Daisy Mugo, Ann Karanu, Linda Moranga, Vivian Oluoch, Jasmit Shah, Julius Mutiso, Alfred Mburu, Zaitun Nneka, Peter Betti, Wanzila Usyu Mutinda, Abdirahman Issak Abdi, Philip Bejon, Lynette Isabella Ochola-Oyier, George M. Warimwe, Eunice Nduati, Francis M. Ndungu
BackgroundGiven the low levels of COVID-19 vaccine coverage in Sub-Saharan Africa, despite high levels of natural SARS-CoV-2 exposures, strategies for extending the breadth and longevity of naturally acquired immunity are warranted. Designing such st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83057719567d4b4ba3611784926593e
https://doi.org/10.1101/2022.10.05.22280716
https://doi.org/10.1101/2022.10.05.22280716
Autor:
Johnstone Makale, Amidou Diarra, Crystal D Karakochuk, Ruth Mitchell, Robert W. Snow, Francis M. Ndungu, Laura M. Raffield, Kirk A. Rockett, Alexander J. Mentzer, Parminder S. Suchdev, John Muthii Muriuki, Rita Wegmüller, Catherine Kyobutungi, Sodiomon B. Sirima, Thomas N. Williams, Dominic P. Kwiatkowski, Moses Gwamaka, Clare L. Cutland, Seth Adu-Afarwuah, Adrian V. S. Hill, Alison M. Elliott, James P. Wirth, Wandia Kimita, Patrick E. Duffy, Caroline Ngetsa, Manjinder S. Sandhu, Andrew M. Prentice, Christine P. Stewart, Kendra A. Byrd, Michal Fried, Alireza Morovat, Emily L. Webb, Alex Macharia, Timothy J. Green, Alfred B. Tiono, Sarah H. Atkinson, Shabir A. Madhi, Reina Engle-Stone, Philip Bejon, George Davey Smith, Alex Ndjebayi, Solomon K. Musani, Swaib A. Lule, Anthony Etyang
Publikováno v:
Nature medicine
muriuki, J, Mentzer, A J, Mitchell, R E, Webb, E L, Etyang, A O, Kyobutungi, C, Morovat, A, Kimita, W, Ndungu, F M, Macharia, A W, Ngetsa, C, Makale, J, Lule, S A, Musani, S K, Raffield, L M, Cutland, C L, Sirima, S B, Diarra, A, Tiono, A B, Fried, M, Gwamaka, M, Adu-Afarwuah, S & Davey Smith, G 2021, ' Malaria is a cause of iron deficiency in African children ', Nature Medicine, vol. 27, no. 4, pp. 653-658 . https://doi.org/10.1038/s41591-021-01238-4
Nature medicine, vol 27, iss 4
muriuki, J, Mentzer, A J, Mitchell, R E, Webb, E L, Etyang, A O, Kyobutungi, C, Morovat, A, Kimita, W, Ndungu, F M, Macharia, A W, Ngetsa, C, Makale, J, Lule, S A, Musani, S K, Raffield, L M, Cutland, C L, Sirima, S B, Diarra, A, Tiono, A B, Fried, M, Gwamaka, M, Adu-Afarwuah, S & Davey Smith, G 2021, ' Malaria is a cause of iron deficiency in African children ', Nature Medicine, vol. 27, no. 4, pp. 653-658 . https://doi.org/10.1038/s41591-021-01238-4
Nature medicine, vol 27, iss 4
Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID1. To test the hypothesis that malaria might cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96de8a1482060483305a4bdc27e6a8a7
http://europepmc.org/articles/PMC7610676
http://europepmc.org/articles/PMC7610676