Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Francis M Ndungu"'
Autor:
Robert M Mugo, Sebastian Rausch, Zaneta D Musimbi, Christina Strube, Marie-Kristin Raulf, Olfert Landt, Paul M Gichuki, Friederike Ebner, Jedidah Mwacharo, Maurice R Odiere, Francis M Ndungu, Doris W Njomo, Susanne Hartmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 6, p e0012279 (2024)
BackgroundThe standard diagnosis of Ascaris lumbricoides and other soil-transmitted helminth (STH) infections relies on the detection of worm eggs by copromicroscopy. However, this method is dependent on worm patency and shows only limited accuracy i
Externí odkaz:
https://doaj.org/article/91077f3cc8424017a2d291e150ef0f27
Autor:
Robert M Mugo, Benedict Orindi, Faiz M Shee, Duncan Bellamy, Jedidah Mwacharo, Katie J Ewer, Philip Bejon, Francis M Ndungu
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286117 (2023)
BackgroundRTS,S/AS01 induced anti-circumsporozoite protein (CSP) IgG antibodies are associated with the vaccine efficacy. There is currently no international standardisation of the assays used in the measurement of anti-CSP IgG antibody concentration
Externí odkaz:
https://doaj.org/article/f791229208084c22b81f445ab3ddbd66
Autor:
Robert M. Mugo, Kennedy Mwai, Jedidah Mwacharo, Faiz M. Shee, Jennifer N. Musyoki, Juliana Wambua, Edward Otieno, Philip Bejon, Francis M. Ndungu
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021)
Abstract Background RTS,S/AS01, the leading malaria vaccine has been recommended by the WHO for widespread immunization of children at risk. RTS,S/AS01-induced anti-CSP IgG antibodies are associated with the vaccine efficacy. Here, the long-term kine
Externí odkaz:
https://doaj.org/article/f3598ba2fe95427294830402b185dbef
Autor:
Eleonora Vianello, PhD, Patricia Gonzalez-Dias, MSc, Suzanne van Veen, BSc, Carmen G Engele, BSc, Edwin Quinten, BSc, Thomas P Monath, MD, Donata Medaglini, ProfPhD, Francesco Santoro, PhD, Angela Huttner, MD, Sheri Dubey, PhD, Michael Eichberg, PhD, Francis M Ndungu, PhD, Peter G Kremsner, ProfMD, Paulin N Essone, PhD, Selidji Todagbe Agnandji, MD, Claire-Anne Siegrist, ProfMD, Helder I Nakaya, PhD, Tom H M Ottenhoff, ProfMD, Mariëlle C Haks, PhD, Selidij T Agnandij, Rafi Ahmed, Jenna Anderson, Floriane Auderset, Philip Bejon, Luisa Borgianni, Jessica Brosnahan, Annalisa Ciabattini, Olivier Engler, Mariëlle C Haks, Ali M Harandi, Donald G Heppner, Alice Gerlini, Angela Huttner, Peter G Kremsner, Donata Medaglini, Thomas P Monath, Francis M Ndungu, Patricia Njuguna, Tom H M Ottenhoff, David Pejoski, Mark Page, Gianni Pozzi, Francesco Santoro, Claire-Anne Siegrist, Sheri Dubey, Michael Eichberg, Essone P Ndong, Kabwende Lumeka, Helder I Nakaya, Patricia Gonzales Dias Carvalho, Sylvia Rothenberger, Eleonora Vianello, Sravya S Nakka, Suzanne van Veen
Publikováno v:
The Lancet Microbe, Vol 3, Iss 2, Pp e113-e123 (2022)
Summary: Background: A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to ident
Externí odkaz:
https://doaj.org/article/9d0108ac7efd4b3a99b85d9af9182e4b
Autor:
Reagan M. Mogire, Alireza Morovat, John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Manjinder S. Sandhu, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Children living in sub-Saharan Africa have a high burden of rickets and infectious diseases, conditions that are linked to vitamin D deficiency. However, data on the vitamin D status of young African children and its environmental
Externí odkaz:
https://doaj.org/article/af36fc5b4df647808f587d75066738fb
Autor:
Peter Jahnmatz, Diana Nyabundi, Christopher Sundling, Linnea Widman, Jedidah Mwacharo, Jennifer Musyoki, Edward Otieno, Niklas Ahlborg, Philip Bejon, Francis M. Ndungu, Anna Färnert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Identifying the mechanism of naturally acquired immunity against Plasmodium falciparum malaria could contribute to the design of effective malaria vaccines. Using a recently developed multiplexed FluoroSpot assay, we assessed cross-sectional pre-exis
Externí odkaz:
https://doaj.org/article/55ade425e9c54d8ebd694c0df15bbb79
Autor:
Mainga Hamaluba, Debra Riako, Betty Kalama, Francis M. Ndungu, Hope Mwangudzah, Saye Khoo, David G. Lalloo, Lawrence Babu, Richard FitzGerald, Michael Abouyannis, Benedict Orindi, Samson Ngome, Mwanajuma Ngama, Yvonne K. Nyambura, Laura Else, Frida Lewa, Noni Mumba, Ifedayo Adetifa, Sujan Dily Penchala, Nicholas R. Casewell
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Snakebites affect over 5 million people each year, and over 100,000 per year die as a result. The only available treatment is antivenom, which has many shortcomings including high cost, intravenous administration, and high risk of adverse
Externí odkaz:
https://doaj.org/article/d23d9447885c40cdb89579bc43c2f874
Autor:
John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Alireza Morovat, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Rosie J. Crane, James A. Berkley, Swaib A. Lule, Clare Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Philip Bejon, Shabir A. Madhi, Adrian V. S. Hill, Andrew M. Prentice, Parminder S. Suchdev, Alison M. Elliott, Thomas N. Williams, Sarah H. Atkinson
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Iron deficiency (ID) is a major public health burden in African children and accurate prevalence estimates are important for effective nutritional interventions. However, ID may be incorrectly estimated in Africa because most meas
Externí odkaz:
https://doaj.org/article/c4b8577e01b24a9aa3d0e11b1e8c3f55
Autor:
Jedida Mwacharo, Matt Berriman, Jean Langhorne, Francis M. Ndungu, Kevin Marsh, Jennifer Musyoki, John W.G. Addy, John Joseph Valletta, Joyce Mwongeli Ngoi, Philip Bejon, Yaw Bediako, Mario Recker, Joshua Wambua, Adam J. Reid, Chris I. Newbold, Khadija Said Mohammed, Edward Otieno
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
After decades of research, our understanding of when and why individuals infected with Plasmodium falciparum develop clinical malaria is still limited. Correlates of immune protection are often sought through prospective cohort studies, where measure
Externí odkaz:
https://doaj.org/article/63369b7637934cea969bd98baf984384
Autor:
John Joseph Valetta, Jedida Mwacharo, Matthew Berriman, Jean Langhorne, Francis M. Ndungu, Kevin Marsh, Jennifer Musyoki, John W.G. Addy, Joyce Mwongeli Ngoi, Yaw Bediako, Philip Bejon, Mario Recker, Joshua Wambua, Adam J. Reid, Edward Otieno, Khadija Said Mohammed
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: Studies of long-term malaria cohorts have provided essential insights into how Plasmodium falciparum interacts with humans, and influences the development of antimalarial immunity. Immunity to malaria is acquired gradually after multiple
Externí odkaz:
https://doaj.org/article/3c6460d553e64a7b9d05aef883a961a6