Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Francis M Kobia"'
Autor:
Francis M Kobia, Kristina Preusse, Quanhui Dai, Nicholas Weaver, Matthew R Hass, Praneet Chaturvedi, Sarah J Stein, Warren S Pear, Zhenyu Yuan, Rhett A Kovall, Yi Kuang, Natanel Eafergen, David Sprinzak, Brian Gebelein, Eric W Brunskill, Raphael Kopan
Publikováno v:
PLoS Biology, Vol 18, Iss 10, p e3000850 (2020)
Cooperative DNA binding is a key feature of transcriptional regulation. Here we examined the role of cooperativity in Notch signaling by CRISPR-mediated engineering of mice in which neither Notch1 nor Notch2 can homo- or heterodimerize, essential for
Externí odkaz:
https://doaj.org/article/56bb8176d92c404f8da9d4b31d6102f3
Publikováno v:
Trends Parasitol
Complications from placental malaria cause poor pregnancy outcomes, including low birthweight, preterm delivery, and stillbirths. Many of these complications are driven by maternal innate proinflammatory responses to the sequestration of Plasmodium f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b586b33e3c810a4b19904cf3ee00fc5f
https://doi.org/10.1016/j.pt.2022.04.002
https://doi.org/10.1016/j.pt.2022.04.002
Publikováno v:
Frontiers in Tropical Diseases. 3
Africa bears the greatest burden of malaria with more than 200 million clinical cases and more than 600,000 deaths in 2020 alone. While malaria-associated deaths dropped steadily until 2015, the decline started to falter after 2016, highlighting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb2d5e2d35e61a1745a0d5e3469e20da
https://doi.org/10.3389/fitd.2022.988665
https://doi.org/10.3389/fitd.2022.988665
Autor:
Raphael Kopan, Brian Gebelein, Francis M. Kobia, Sarah J. Stein, Rhett A. Kovall, Warren S. Pear, Kristina Preusse, Quanhui Dai, Yi Kuang, David Sprinzak, Natanel Eafergen, Eric W. Brunskill, Praneet Chaturvedi, Nicholas Weaver, Matthew R. Hass, Zhenyu Yuan
Publikováno v:
PLoS Biology
PLoS Biology, Vol 18, Iss 10, p e3000850 (2020)
PLoS Biology, Vol 18, Iss 10, p e3000850 (2020)
Cooperative DNA binding is a key feature of transcriptional regulation. Here we examined the role of cooperativity in Notch signaling by CRISPR-mediated engineering of mice in which neither Notch1 nor Notch2 can homo- or heterodimerize, essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a9475d271e0979f0f791d9d3588804
https://pubmed.ncbi.nlm.nih.gov/33017398
https://pubmed.ncbi.nlm.nih.gov/33017398
Autor:
Francis M. Kobia, Kristina Preusse, Quanhui Dai, Nicholas Weaver, Praneet Chaturvedi, Sarah J. Stein, Warren S. Pear, Zhenyu Yuan, Rhett A. Kovall, Yi Kuang, Natanel Eafergen, David Sprinzak, Brian Gebelein, Eric Brunskill, Raphael Kopan
Cooperative DNA binding is a key feature of transcriptional regulation. Here we examined the role of cooperativity in Notch signaling by CRISPR-mediated engineering of mice in which neither Notch1 nor Notch2 can homo- or heterodimerize, essential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a8ebf6692c3d81de30f3c267edb9ec
