Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Francis Kruszewski"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 95:353-362
The effect of expression time (the time between the end of the treatment period and the first exposure to selective medium) on the frequency of benzo[ a ]pyrene(BP)-induced mutations at the HGPRT (hypoxanthine-guanine phosphoribosyl transferase 2.4.2
Publikováno v:
Carcinogenesis. 1:871-875
The liver-derived human cell line, Hep G2, has high benzo[a]pyrene-metabolizing activity and converts benzo[a]pyrene to intermediates that are mutagenic and that bind to DNA. This cell line will be useful for studying metabolic activation of polycycl