Long-term nitrofurantoin: an analysis of complication awareness, monitoring, and pulmonary injury cases

Autor: Toby Peter Speirs, Nicole Tuffin, Finlay Mundy-Baird, Helena Sakota, Sarah Mulholland, Michelle Westlake, Max Lyon, Andrew R Medford, Charles Sharp, Michael Darby, Mahableshwar Albur, Francis Keeley, Helena Burden, Charlie Kenward, Elizabeth Jonas, Shaney Barratt, Huzaifa I Adamali

Publikováno v: BJGP Open, Vol 5, Iss 6 (2021)

Background: Long-term nitrofurantoin (NF) treatment can result in pulmonary and hepatic injury. Current guidelines do not outline the type or frequency of monitoring required for detection of these injuries. Aim: To assess 1) awareness of NF complica

Externí odkaz: https://doaj.org/article/47788a09f7fa4530ae7fd7d26833f2e9

An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment

Autor: Marcus Jepson, Daisy Elliott, Carmel Conefrey, Julia Wade, Leila Rooshenas, Caroline Wilson, David Beard, Jane M. Blazeby, Alison Birtle, Alison Halliday, Rob Stein, Jenny L. Donovan, Andrew Carr, Jonathan Cook, Cushla Cooper, Benjamin Dean, Alastair Gray, Stephen Gwilym, Andrew Judge, Naomi Merritt, Jane Moser, Jonathan Rees, Ines Rombach, Julian Savulescu, Irene Tracey, Karolina Wartolowska, Paul Barham, Sara T. Brookes, Tom Crosby, Stephen J. Falk, S. Michael Griffin, William Hollingworth, Andrew D. Hollowood, Richard Krysztopik, Wyn Lewis, Jo Nicklin, Christopher Streets, Sean Strong, Dan Titcomb, Geraint Williams, Rik Bryan, James Catto, John Chester, Ann French, Emma Hall, Chris Harris, Mark Johnson, Rob Jones, Francis Keeley, Tony Kirkbank, Roger Kockelbergh, Rebecca Lewis, Michelle Newton, Thomas Powles, Rachel Waters, Andrew Winterbottom, Jean-Pierre Becquemin, Anna Belli, Marc Bosiers, Piergiorgio Cao, Christina Davies, Michael Gough, Elizabeth Hayter, Peter Leopold, Sumaira McDonald, Jonathan Michaels, Borislava Mihaylova, Richard Peto, Steven Robertson, Peter Rothwell, Rachael Scott, Dafydd Thomas, Frank Vermassen, John Bartlett, David Cameron, Amy Campbell, Peter Canney, Janet Dunn, Helena Earl, Mary Falzon, Adele Francis, Peter Hall, Victoria Harmer, Helen Higgins, Louise Hiller, Luke Hughes-Davies, Claire Hulme, Iain Macpherson, Andreas Makris, Andrea Marshall, Christopher McCabe, Adrienne Morgan, Sarah Pinder, Christopher Poole, Daniel Rea, Nigel Stallard

Publikováno v: Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D J, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Beard, D J, Carr, A, Cook, J A, Cooper, C, Dean, B, Donovan, J L, Gray, A, Gwilym, S, Judge, A, Merritt, N, Moser, J, Rees, J, Rombach, I, Savulescu, J, Tracey, I, Wartolowska, K, Blazeby, J M, Barham, P, Brookes, S T, Crosby, T, Donovan, J L, Falk, S J, Griffin, S M, Hollingworth, W, Hollowood, A D, Krysztopik, R, Lewis, W, Nicklin, J, Streets, C, Strong, S, Titcomb, D, Williams, G, Birtle, A, Bryan, R, Catto, J W, Chester, J, Donovan, J L, French, A, Hall, E, Harris, C, Johnson, M, Jones, R, Keeley, F, Kirkbank, T, Kockelbergh, R, Lewis, R, Newton, M, Powles, T, Waters, R A, Winterbottom, A, Halliday, A, Becquemin, J, Belli, A, Bosiers, M, Cao, P, Davies, C, Donovan, J L, Gray, A, Gough, M, Hayter, E, Leopold, P, Mcdonald, S, Michaels, J, Mihaylova, B, Peto, R, Robertson, S, Rothwell, P M, Scott, R, Thomas, D A, Vermassen, F, Stein, R, Bartlett, J, Cameron, D, Campbell, A, Canney, P, Donovan, J L, Dunn, J, Earl, H, Falzon, M, Francis, A, Hall, P, Harmer, V, Higgins, H, Hiller, L, Hughes-Davies, L, Hulme, C, Macpherson, I R, Makris, A, Marshall, A, McCabe, C, Morgan, A, Pinder, S, Poole, C J, Rea, D W & Stallard, N 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology . https://doi.org/10.1016/j.jclinepi.2018.02.018
Journal of Clinical Epidemiology
Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ', Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . https://doi.org/10.1016/j.jclinepi.2018.02.018
Jepson, M, Elliott, D, Conefrey, C, Wade, J, Rooshenas, L, Wilson, C, Beard, D, Blazeby, J M, Birtle, A, Halliday, A, Stein, R, Donovan, J L, Chemorad Study Group 2018, ' An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment ' Journal of Clinical Epidemiology, vol. 99, pp. 75-83 . DOI: 10.1016/j.jclinepi.2018.02.018

Objectives To explore how the concept of randomization is described by clinicians and understood by patients in randomized controlled trials (RCTs) and how it contributes to patient understanding and recruitment. Study Design and Setting Qualitative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2949775783d47a2990fa4feffea099b1
https://www.pure.ed.ac.uk/ws/files/65042302/PH_open_access.pdf