Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Francis K. Yoshimoto"'
Publikováno v:
Organic & Biomolecular Chemistry. 21:3172-3176
Menarandroside A, which bears a 12α-hydroxypregnenolone steroid backbone, was isolated from the plant, Cynanchum menarandrense. This natural product was synthesized from dehydroepiandrosterone (DHEA).
Autor:
Hadi D. Arman, Tu M. Ho, Kaitlyn Varela, Cynthia S. Veliz, Richard B. Zanni, Armando Rodriguez, Zhiwei Wang, Francis K. Yoshimoto
Publikováno v:
Journal of Chemical Education.
Autor:
Kaitlyn Varela, Hafij Al Mahmud, Hadi D. Arman, Luis R. Martinez, Catherine A. Wakeman, Francis K. Yoshimoto
Publikováno v:
J Nat Prod
Dihydroartemisinic acid (DHAA) is a plant natural product that undergoes a spontaneous endoperoxide-forming cascade reaction to yield artemisinin in the presence of air. The endoperoxide functional group gives artemisinin its biological activity that
Publikováno v:
Journal of Natural Products. 84:1967-1984
Artemisinin is the plant natural product used to treat malaria. The endoperoxide bridge of artemisinin confers its antiparasitic properties. Dihydroartemisinic acid is the biosynthetic precursor of artemisinin that was previously shown to nonenzymati
Publikováno v:
The Protein Journal
Coronavirus disease 2019 (COVID-19), which is the pandemic caused by the virus, severe acute respiratory syndrome coronavirus-2 (SARS CoV-2), first appearing in December 2019, continues to confound the world. In this update we provide insights into h
Autor:
Francis K. Yoshimoto
Publikováno v:
The Protein Journal
The global pandemic that shut down the world in 2020 was caused by the virus, SARS CoV-2. The chemistry of the various nonstructural proteins (NSP3, NSP5, NSP12, NSP13, NSP14, NSP15, NSP16) of SARS CoV-2 is discussed. Secondly, a recent major focus o
Publikováno v:
Journal of Natural Products. 83:66-78
Dihydroartemisinic acid is the biosynthetic precursor to artemisinin, the endoperoxide-containing natural product used to treat malaria. The conversion of dihydroartemisinic acid to artemisinin is a cascade reaction that involves C-C bond cleavage, h
Publikováno v:
Steroids. 186:109088
The Schönecker oxidation involves the 12beta-hydroxylation of 17-imino pyridine DHEA derivatives using copper and either molecular oxygen or hydrogen peroxide as the oxidant. In this study, a 19-imino pyridine DHEA derivative was synthesized and was
Publikováno v:
Journal of natural products. 84(7)
Artemisinin is the plant natural product used to treat malaria. The endoperoxide bridge of artemisinin confers its antiparasitic properties. Dihydroartemisinic acid is the biosynthetic precursor of artemisinin that was previously shown to nonenzymati
Autor:
Tapiwa Chiura, Ian Davis, Zehava Eichenbaum, Aimin Liu, Jiafeng Geng, Piotr J. Mak, Ankita J Sachla, Francis K. Yoshimoto, Jiasong Li, Ephrahime S Traore
Publikováno v:
Molecules, Vol 26, Iss 549, p 549 (2021)
Molecules
Volume 26
Issue 3
Molecules
Volume 26
Issue 3
HupZ is an expected heme degrading enzyme in the heme acquisition and utilization pathway in Group A Streptococcus. The isolated HupZ protein containing a C-terminal V5-His6 tag exhibits a weak heme degradation activity. Here, we revisited and charac