Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Francis K L Chan"'
Autor:
Yating Wan, Oscar W.H. Wong, Hein M Tun, Qi Su, Zhilu Xu, Whitney Tang, Suk Ling Ma, Sandra Chan, Francis K L Chan, Siew C Ng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Accumulating evidence suggests that gut microbiota alterations influence brain function and could serve as diagnostic biomarkers and therapeutic targets. The potential of using fecal microbiota signatures to aid autism spectrum disorder (ASD) detecti
Externí odkaz:
https://doaj.org/article/2fcb62ce83bd490dbc63e8a1c6fc52ad
Autor:
Martin C S Wong, Jessica Y L Ching, Victor C W Chan, Renee Bruggemann, Thomas Y T Lam, Arthur K C Luk, Justin C Y Wu, Francis K L Chan, Joseph J Y Sung
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125782 (2015)
Very few studies examined the issue of regret on choosing colorectal cancer (CRC) screening tests. We evaluated the determinants of regret and tested the hypothesis that regret over screening choices was associated with poorer screening compliance.A
Externí odkaz:
https://doaj.org/article/4a5d3260ab5b4ee19ad8092b652b2680
Autor:
Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Zhi J Li, Xiao J Wang, Clover C M Wong, Lin Zhang, Simon S M Ng, Franky L Chan, Francis K L Chan, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131750 (2015)
Externí odkaz:
https://doaj.org/article/35ca5c9f1ba944b285399c946bd680d6
Autor:
Martin C S Wong, Hoyee W Hirai, Arthur K C Luk, Thomas Y T Lam, Jessica Y L Ching, Sian M Griffiths, Francis K L Chan, Joseph J Y Sung
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60366 (2013)
ObjectivesWe tested the a priori hypothesis that self-perceived and real presences of risks for colorectal cancer (CRC) are associated with better knowledge of the symptoms and risk factors for CRC, respectively.MethodsOne territory-wide invitation f
Externí odkaz:
https://doaj.org/article/688d470049fc40b48f748a49a0f85b71
Autor:
Martin C S Wong, Jessica Y L Ching, Hoyee H Hirai, Thomas Y T Lam, Sian M Griffiths, Francis K L Chan, Joseph J Y Sung
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70209 (2013)
PURPOSE: to evaluate the proportion of self-referred screening participants having various psychological barriers and the factors associated with these barriers. METHODS: A territory-wide bowel cancer screening centre sent an invitation via the media
Externí odkaz:
https://doaj.org/article/30bddba219b64abdb95908e8a7cc64c7
Autor:
Chung-Wah Wu, Yu-Juan Dong, Qiao-Yi Liang, Xin-Qi He, Simon S M Ng, Francis K L Chan, Joseph J Y Sung, Jun Yu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57036 (2013)
BACKGROUND: miR-18a is one of the most up-regulated miRNAs in colorectal cancers (CRC) based on miRNA profiling. In this study, we examined the functional significance of miR-18a in CRC. METHODS: Expression of miR-18a was investigated in 45 CRC patie
Externí odkaz:
https://doaj.org/article/caab2cd551a84d5aaa88de34755a1513
Autor:
Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Zhi J Li, Xiao J Wang, Clover C M Wong, Lin Zhang, Simon S M Ng, Franky L Chan, Francis K L Chan, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63641 (2013)
Host immune peptides, including cathelicidins, have been reported to possess anticancer properties. We previously reported that LL-37, the only cathelicidin in humans, suppresses the development of colon cancer. In this study, the potential anticance
Externí odkaz:
https://doaj.org/article/85ffa082b02c4ced8fd856790832beeb
Autor:
Ya C Wu, Xiao J Wang, Le Yu, Francis K L Chan, Alfred S L Cheng, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37572 (2012)
Hydrogen sulfide (H(2)S) is a gaseous bacterial metabolite that reaches high levels in the large intestine. In the present study, the effect of H(2)S on the proliferation of normal and cancerous colon epithelial cells was investigated. An immortalize
Externí odkaz:
https://doaj.org/article/04ddac0834be4a8a83cff3afb6bc7307
Autor:
Francis K L Chan, Martin C S Wong, Andrew T Chan, James E East, Han-Mo Chiu, Govind K Makharia, David Weller, Choon Jin Ooi, Julajak Limsrivilai, Yutaka Saito, Dao V Hang, Jon D Emery, Dadang Makmun, Kaichun Wu, Raja Affendi Raja Ali, Siew C Ng
Publikováno v:
Chan, F K L, Wong, M C S, Chan, A T, East, J E, Chiu, H-M, Makharia, G K, Weller, D, Ooi, C J, Limsrivilai, J, Saito, Y, Hang, D V, Emery, J D, Makmun, D, Wu, K, Ali, R A R & Ng, S C 2023, ' Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia ', Gut, vol. 72, no. 7, 329429, pp. 1240-1254 . https://doi.org/10.1136/gutjnl-2023-329429
Screening for colorectal cancer (CRC) is effective in reducing CRC related mortality. Current screening methods include endoscopy based and biomarker based approaches. This guideline is a joint official statement of the Asian Pacific Association of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04adeac2833cd5ce20963dea290b7f55
https://hdl.handle.net/20.500.11820/d4d4cc85-be85-4767-836d-4dea4bd5ab92
https://hdl.handle.net/20.500.11820/d4d4cc85-be85-4767-836d-4dea4bd5ab92
Publikováno v:
Oncogene. 41:3485-3497
We identified gamma-glutamyltransferase 7 (GGT7) to be frequently downregulated in gastric cancer, but its role remains unknown. Here we elucidated the clinical significance, functional roles, and molecular mechanism of GGT7 in gastric cancer. GGT7 w