Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Francis J. Saunders"'
Publikováno v:
Journal of Biological Chemistry. 210:709-712
Publikováno v:
Endocrinology. 62:798-803
17α-Methyl-17-hydroxy-5(10)-estren-3-one (SC-6582) possessed approximately 11 to 40% the activity of estrone in depressing the plasma cholesterolphospholipid ratio in cholesterol-fed cockerels, whereas, it had only 0.1 to 0.9% the activity of estron
Autor:
Francis J. Saunders
Publikováno v:
Endocrinology. 77:873-878
Estrogens administered to rats during the first few days post coitum inhibit nidation. Norethynodrel, which has 3-7 % the estrogenicity of estrone, was approximately 2 % as effective in inhibiting nidation in rats. Both mestranol and norethynodrel wi
Autor:
Francis J. Saunders
Publikováno v:
Endocrinology. 49:185-188
THE adrenal gland has been suspected of involvement in allergic conditions for over 20 years. In an early paper Wyman (1929) reported that adrenalectomized rats with adrenal transplants in the abdominal muscles were as susceptible to histamine poison
Publikováno v:
Acta Endocrinologica. 41:381-390
17α-Ethynyl-4-estrene-3,17-diol and its C-3 and C-17 esterified analogues were studied for progestational, oestrogenic and androgenic properties. In addition, oestrogen-antagonistic and anti-progestational effects were determined and compared with t
Autor:
Francis J. Saunders
Publikováno v:
Endocrinology. 58:412-419
SAUNDERS (1951) reported that lipo-adrenal extract decreased the number of fatalities in sensitized adrenalectomized mice challenged with the antigen while desoxycorticosterone (DOC) offered no protection. These experiments have now been extended to
Autor:
R. E. Ranney, Francis J. Saunders
Publikováno v:
Experimental Biology and Medicine. 116:596-599
SummaryAn assay was devised in which the hypocholesterolemic action of parenterally administered androsterone could be demonstrated in rats given a low dose of propyl-thiouracil. Using this procedure an analogue of androsterone, 3α-methoxy-17α-meth
Autor:
Francis J. Saunders, Victor A. Drill
Publikováno v:
Endocrinology. 58:567-572
WHILE adequate assay procedures have long been available to determine the androgenic effects of steroids, there was no satisfactoryrapid method of assaying their anabolic effects until development of the levator ani technique by Eisenberg and Gordan
Autor:
Francis J. Saunders, Victor A. Drill
Publikováno v:
Experimental Biology and Medicine. 94:646-649
SummaryThe androgenic and anabolic effects of testosterone, testosterone propionate, methyl testosterone, methyl androstenediol, androstanolone and 17-ethyl-19-nortestosterone (Nilevar) were compared. The greatest androgenic responses were obtained w
Autor:
Francis J. Saunders, Richard L. Elton
Publikováno v:
Toxicology and Applied Pharmacology. 11:229-244
Ethynodiol diacetate and mestranol, separately or in combination, prevent establishment of pregnancy in rats and rabbits when administered in sufficient dosage. This property is common to estrogens in these species. Treatment of pregnant rats with et