Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Francis J. Persico"'
Publikováno v:
Journal of Medicinal Chemistry. 35:3180-3183
A novel series of N-[(2-benzothiazolylthio)alkyl]-N'-hydroxyurea derivatives (9-25) was synthesized and evaluated for biological activity as inhibitors of 5-lipoxygenase both in vivo (mouse zymosan peritonitis assay) and in vitro (Ca2+ ionophore-stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee031c931391fb4716911242f595277
https://doi.org/10.1021/jm00095a012
https://doi.org/10.1021/jm00095a012
Publikováno v:
Immunopharmacology. 8:171-174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::638033cf38939e76c32ecea0cbde0178
https://doi.org/10.1016/0162-3109(84)90022-5
https://doi.org/10.1016/0162-3109(84)90022-5
Publikováno v:
Prostaglandins. 32:563-577
5,8,11,14-Eicosatetraynoic acid (ETYA), a compound which inhibits both the cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism, antagonized the contraction of segments of guinea-pig ileal longitudinal muscle produced by SRS-A (IC5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c65bf927c9df6003885074db3437298
https://doi.org/10.1016/0090-6980(86)90038-9
https://doi.org/10.1016/0090-6980(86)90038-9
Publikováno v:
Angiology. 31:320-330
It has been postulated that flunarizine's ability to increase tissue perfusion may be due to either antivasoconstrictor activity, or its effects on red blood cell deformability, or both. In studies reported here, the ability of flunarizine to in flue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ea055a12a5f98244c4dc16ad3254d2
https://doi.org/10.1177/000331978003100503
https://doi.org/10.1177/000331978003100503
Autor:
Francis J. Persico, A. Arthur Gottlieb
Publikováno v:
Nature New Biology. 239:173-176
INTEREST in the viral RNA-dependent DNA polymerases1,2 has led to an examination of mammalian DNA polymerases and to the characterization in certain systems of DNA polymerases which can transcribe ribopolymer chains of appropriate ribopolymer-oligode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b50d2b206d7b31c811adf14989393dd
https://doi.org/10.1038/newbio239173a0
https://doi.org/10.1038/newbio239173a0
Autor:
Diarmuid E. Nicholson, Otto J. Plescia, Francis J. Persico, Alan H. Smith, A. Arthur Gottlieb
Publikováno v:
Nature. 246:480-482
WE have previously reported the existence of several DNA polymerases in the murine myeloma line, MOPC-21 (refs 1 and 2). Two of these polymerases, which we refer to as R-1 and R-2, are capable of synthesising poly(dT) on a poly(rA)·oligo(dT)12–18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d30691eacdb7491dbf83a196fc6cb53
https://doi.org/10.1038/246480a0
https://doi.org/10.1038/246480a0
Publikováno v:
Annals of the New York Academy of Sciences. 540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd01775cc4ce40ced5aa419badd611b7
https://pubmed.ncbi.nlm.nih.gov/2462840
https://pubmed.ncbi.nlm.nih.gov/2462840
Publikováno v:
Journal of medicinal chemistry. 29(6)
A series of 12-(cyclic alkylamino)-6H-indolo[2,1-c][1,4]benzodiazepines were synthesized that possess antihistamine and antiserotonin activities as well as ability to inhibit mediator release. Compound 6a, 12-(4-methyl-1-piperazinyl)-6H-indolo[2,1-c]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62707c5400bc6956e34c3b54c9ec7504
https://pubmed.ncbi.nlm.nih.gov/2872333
https://pubmed.ncbi.nlm.nih.gov/2872333
Publikováno v:
Chemischer Informationsdienst. 17
A series of 12-(cyclic alkylamino)-6H-indolo[2,1-c][1,4]benzodiazepines were synthesized that possess antihistamine and antiserotonin activities as well as ability to inhibit mediator release. Compound 6a, 12-(4-methyl-1-piperazinyl)-6H-indolo[2,1-c]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33abac4edd16d156a30ca2bbb1f8f9f2
https://doi.org/10.1002/chin.198644243
https://doi.org/10.1002/chin.198644243
Publikováno v:
Cellular immunology. 113(2)
Balb/3T3 fibroblasts respond to interleukin-1 (IL-1) by proliferating in a dose-dependent fashion. Increasing proliferative responses were observed with increasing IL-1 concentration in serum-free medium when the medium was supplemented with insulin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e28c821f43707a9bbfdd09008babf5b
https://pubmed.ncbi.nlm.nih.gov/3282679
https://pubmed.ncbi.nlm.nih.gov/3282679