Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Francis J P Ebling"'
Autor:
David M Loczenski-Brown, Sarah Jones, Jeni Luckett, Zoe Daniel, Madelaine C Brearley, Francis J P Ebling, Tim Parr, John M Brameld
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218970 (2019)
We previously identified PEPCK-M (encoded by the Pck2 gene) to be highly up-regulated in skeletal muscle of pigs treated with Ractopamine, an anabolic beta-adrenergic receptor agonist. To determine whether PEPCK-M had a causative role in modulating t
Externí odkaz:
https://doaj.org/article/ce45a43db3ba476a8eba772051145243
Autor:
Carlo Lisci, Jo E Lewis, Zoe C T R Daniel, Tyler J Stevenson, Chloe Monnier, Hayley J Marshall, Maxine Fowler, Francis J P Ebling, Gian-Luca Ferri, Cristina Cocco, Preeti H Jethwa
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221517 (2019)
TLQP-21, a peptide encoded by the highly conserved vgf gene, is expressed in neuroendocrine cells and has been the most prominent VGF-derived peptide studied in relation to control of energy balance. The recent discovery that TLQP-21 is the natural a
Externí odkaz:
https://doaj.org/article/85a1a827b7864079b0362602eb3aeff3
Autor:
David M Brown, Sarah Jones, Zoe C T R Daniel, Madelaine C Brearley, Jo E Lewis, Francis J P Ebling, Tim Parr, John M Brameld
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201481 (2018)
Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), wo
Externí odkaz:
https://doaj.org/article/5bdead5ccbf14368938869e7b13b2b57
Autor:
Jo E Lewis, John M Brameld, Phil Hill, Cristina Cocco, Barbara Noli, Gian-Luca Ferri, Perry Barrett, Francis J P Ebling, Preeti H Jethwa
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172724 (2017)
VGF (non-acronymic) was first highlighted to have a role in energy homeostasis through experiments involving dietary manipulation in mice. Fasting increased VGF mRNA in the Arc and levels were subsequently reduced upon refeeding. This anabolic role f
Externí odkaz:
https://doaj.org/article/f090a05ab7d6438785b8cf54fba6a436
Autor:
Himanshu Kharkwal, Farhat Batool, Frank Koentgen, David R Bell, David A Kendall, Francis J P Ebling, Ian R Duce
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187959 (2017)
Cytochrome P450 4x1 (Cyp4x1) is expressed at very high levels in the brain but the function of this protein is unknown. It has been hypothesised to regulate metabolism of fatty acids and to affect the activity of endocannabinoid signalling systems, w
Externí odkaz:
https://doaj.org/article/a951ee8c28ec47a3ba7837f898eaae29
Autor:
Jo E Lewis, John M Brameld, Phil Hill, Cristina Cocco, Barbara Noli, Gian-Luca Ferri, Perry Barrett, Francis J P Ebling, Preeti H Jethwa
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182594 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0172724.].
Externí odkaz:
https://doaj.org/article/9266507418ab43f1888a5360394ce0a2
Autor:
Barbara Noli, Carla Brancia, Roberta Pilleri, Filomena D'Amato, Irene Messana, Barbara Manconi, Francis J P Ebling, Gian-Luca Ferri, Cristina Cocco
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141193 (2015)
VGF mRNA is induced in specific hypothalamic areas of the Siberian hamster upon exposure to short photoperiods, which is associated with a seasonal decrease in appetite and weight loss. Processing of VGF generates multiple bioactive peptides, so the
Externí odkaz:
https://doaj.org/article/17cc66488cc84c4aaf62d6039b0fdf56
Autor:
Annika Herwig, Emmely M de Vries, Matei Bolborea, Dana Wilson, Julian G Mercer, Francis J P Ebling, Peter J Morgan, Perry Barrett
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62003 (2013)
Exposure to short days (SD) induces profound changes in the physiology and behaviour of Siberian hamsters, including gonadal regression and up to 30% loss in body weight. In a continuous SD environment after approximately 20 weeks, Siberian hamsters
Externí odkaz:
https://doaj.org/article/05233fa64d294ae3be71f6777566a6fe
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37496 (2012)
Glutamate neurotransmission and the N-methyl-D-aspartate receptor (NMDAR) are central to photic signaling to the master circadian pacemaker located in the hypothalamic suprachiasmatic nucleus (SCN). NMDARs also play important roles in brain developme
Externí odkaz:
https://doaj.org/article/6af41180f3d34642ae308ec340582d4c
Autor:
Daniel R Ward, Fiona M Dear, Ian A Ward, Susan I Anderson, Daniel J Spergel, Paul A Smith, Francis J P Ebling
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5322 (2009)
Secretion of gonadotropin-releasing hormone (GnRH) produced in neurons in the basal forebrain is the primary regulator of reproductive maturation and function in mammals. Peptidergic signals relating to circadian timing and energy balance are an impo
Externí odkaz:
https://doaj.org/article/feec96e04b36481e808cf25dd20b12b5