Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Francis J, Carr"'
Autor:
Christopher M. Gromisch, Glaiza L. A. Tan, Khristine Amber Pasion, Ann-Marie Moran, Matthew S. Gromisch, Mark W. Grinstaff, Francis J. Carr, Victoria L. M. Herrera, Nelson Ruiz-Opazo
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-21 (2021)
Abstract Background Pancreatic peritoneal carcinomatosis (PPC), with the worst median overall-survival (mOS), epitomizes the incurability of metastatic cancer. Cancer stem cells (CSCs) underpin this incurability. However, inhibitors of CSC-stemness f
Externí odkaz:
https://doaj.org/article/5ea42cacfaf84367ad190f7c6d297db5
Autor:
Mark W. Grinstaff, Khristine A. Pasion, Nelson Ruiz-Opazo, Francis J. Carr, Matthew S. Gromisch, Christopher M. Gromisch, Victoria L. M. Herrera, Glaiza A. Tan, Ann-Marie Moran
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-21 (2021)
Background Pancreatic peritoneal carcinomatosis (PPC), with the worst median overall-survival (mOS), epitomizes the incurability of metastatic cancer. Cancer stem cells (CSCs) underpin this incurability. However, inhibitors of CSC-stemness fail to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749b69a0a0bbb94a12557419c348f64b
https://doaj.org/article/5ea42cacfaf84367ad190f7c6d297db5
https://doaj.org/article/5ea42cacfaf84367ad190f7c6d297db5
Autor:
Christopher M, Gromisch, Glaiza L A, Tan, Khristine Amber, Pasion, Ann-Marie, Moran, Matthew S, Gromisch, Mark W, Grinstaff, Francis J, Carr, Victoria L M, Herrera, Nelson, Ruiz-Opazo
Publikováno v:
BMC Cancer
Background Pancreatic peritoneal carcinomatosis (PPC), with the worst median overall-survival (mOS), epitomizes the incurability of metastatic cancer. Cancer stem cells (CSCs) underpin this incurability. However, inhibitors of CSC-stemness fail to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d777157fc93d85313a1cbb237058fd7
https://pubmed.ncbi.nlm.nih.gov/33853558
https://pubmed.ncbi.nlm.nih.gov/33853558
Autor:
Tim Jones, Matthew P. Baker, Francis J. Carr, Mark H. Fogg, Robert George Edward Holgate, Arron Hearn, Javier Lacadena, Kurt R. Gehlsen, Dorota Kozub
Publikováno v:
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
Protein Engineering, Design and Selection
E-Prints Complutense. Archivo Institucional de la UCM
instname
Universidad Complutense de Madrid
Protein Engineering, Design and Selection
E-Prints Complutense. Archivo Institucional de la UCM
instname
Fungal ribotoxins that block protein synthesis can be useful warheads in the context of a targeted immunotoxin. α-Sarcin is a small (17 kDa) fungal ribonuclease produced by Aspergillus giganteus that functions by catalytically cleaving a single phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209fe0a1eed852bfde9eaf83aad40f8f
Autor:
Francis J. Carr, Matthew P. Baker
Publikováno v:
Current drug safety. 5(4)
Protein therapeutics offer distinct advantages over other classes of drugs largely due to the high level of target specificity and generally low toxicity. Problems have, however, been encountered with some protein therapeutics inducing undesirable im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b7c34ef2376e0f53b232c677696fad
https://pubmed.ncbi.nlm.nih.gov/20615174
https://pubmed.ncbi.nlm.nih.gov/20615174
The screening of a λgt11 library with monoclonal antibodies described here is a relatively uncomplicated procedure, but it requires a little introduction nevertheless. For simplicity, it is assumed that you have in your possession a library that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096b8dffe9372120d2464907e66ea323
https://doi.org/10.1385/0-89603-204-3:451
https://doi.org/10.1385/0-89603-204-3:451
Whereas the expression of foreign genes in mammalian cells usually proves successful, the purification of gene products is often a difficult and time-consuming process. The availability of monoclonal antibodies to the foreign protein can greatly assi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5b70863f214099a03c0567a8812dec
https://doi.org/10.1385/0-89603-204-3:461
https://doi.org/10.1385/0-89603-204-3:461
Autor:
Kenneth O. Lloyd, Pilar Garin-Chesa, Elisabeth Stockert, Sydney Welt, Kathryn L. Armour, Thomas P. Wallace, Kunio Kitamura, William J. Harris, Francis J. Carr, Lloyd J. Old
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(26)
Le(y)-reactive monoclonal antibodies (mAbs) were generated in mice by immunization with synthetic Le(y) neoglycoproteins or with Le(y)-expressing cells. Serological analysis indicated that mAbs raised against synthetic Le(y) (i) reacted strongly with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d9cef156d1fa0fb15a9c01ecc3d6ad
https://pubmed.ncbi.nlm.nih.gov/7809154
https://pubmed.ncbi.nlm.nih.gov/7809154
Publikováno v:
Molecular biotechnology. 1(3)
An expression system is described whereby a gene product is expressed fused to an antibody Fab fragment to form an antibody-like molecule. The antigen binding function of the original antibody is retained and the foreign gene replaces the CH2 and CH3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5091c25354f923f0ac63ad9a2fa2e05d
https://pubmed.ncbi.nlm.nih.gov/7859164
https://pubmed.ncbi.nlm.nih.gov/7859164
Publikováno v:
Biochemical Society transactions. 18(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12ce415ee3ea3d26c5eab5f58d6e4e2
https://pubmed.ncbi.nlm.nih.gov/2088849
https://pubmed.ncbi.nlm.nih.gov/2088849