CYP1A1 induction in the colon by serum: involvement of the PPARα pathway and evidence for a new specific human PPREα site.

Autor: Pierre-Henri Villard, Fabrice Barlesi, Martine Armand, Thi-Mai-Anh Dao, Jean-Marc Pascussi, Francis Fouchier, Serge Champion, Claire Dufour, Christian Giniès, Ayman Khalil, Marie-Josephe Amiot, Yves Barra, Eric Seree

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e14629 (2011)

BACKGROUND: We previously showed that blood serum induced cytochrome P450 1A1 (CYP1A1) monooxygenase expression in vitro. OBJECTIVE: Our purpose was (i) to identify the molecular mechanism involved and (ii) to characterize the inducer compound(s) in

Externí odkaz: https://doaj.org/article/b604336f230c4e45b3ddb6c821b4710e

Integrin αvβ6 mediates HT29-D4 cell adhesion to MMP-processed fibrinogen in the presence of Mn2+

Autor: Francis Fouchier, Claude Penel, Patricia Bremond, Marie Pierre Montero, Serge Champion

Publikováno v: European Journal of Cell Biology. 86:143-160

Mn(2+) was found to induce adhesion of HT29-D4 adenoma carcinoma cells to fibrinogen (Fb). This was independent of the expression of the beta3 integrin subunit and involved endogenous alphavbeta6 but not alphavbeta5 integrin. Thus, addition of Mn(2+)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd502e1ab9bbbf180f7bd07c26c7da7
https://doi.org/10.1016/j.ejcb.2006.12.002

Modulation of the superoxide anion production and MMP-9 expression in PMA stimulated THP-1 cells by olive oil minor components: Tyrosol and hydroxytyrosol

Autor: Samia Dabbou, Francis Fouchier, Amel Nakbi, Sounira Mehri, N. Attia, Claude L. Léger, Mohamed Hammami, Serges Champion

Publikováno v: Food Research International
Food Research International, Elsevier, 2011, 44 (2), pp.575-581. ⟨10.1016/j.foodres.2010.12.010⟩

Publication Inra prise en compte dans l'analyse bibliométrique des publications scientifiques mondiales sur les Fruits, les Légumes et la Pomme de terre. Période 2000-2012. http://prodinra.inra.fr/record/256699; International audience; Extra virgi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b478c72790d1597018bc8d53e6d7a68e
https://hal.inrae.fr/hal-02649272

Polycyclic aromatic hydrocarbons potentiate high-fat diet effects on intestinal inflammation

Autor: Rémy Burcelin, Yves Barra, Serge Champion, Francis Fouchier, P.H. Villard, Eric Seree, Maih Anh Dao, Jean-François Savouret, Ayman Khalil

Publikováno v: Toxicology Letters
Toxicology Letters, 2010, 196 (3), pp.161-167. ⟨10.1016/j.toxlet.2010.04.010⟩
Toxicology Letters, Elsevier, 2010, 196 (3), pp.161-7. ⟨10.1016/j.toxlet.2010.04.010⟩
Toxicology Letters, Elsevier, 2010, 196 (3), pp.161-167. ⟨10.1016/j.toxlet.2010.04.010⟩
Toxicology Letters, Elsevier, 2010, 196 (3), pp.161-7. 〈10.1016/j.toxlet.2010.04.010〉
Toxicology Letters, 2010, 196 (3), pp.161-7. ⟨10.1016/j.toxlet.2010.04.010⟩

International audience; We demonstrate that intestinal inflammation caused by high-fat diet is increased by the environmental contaminant benzo[a]pyrene. Our in vivo results indicate that a high-fat diet (HFD) induces a pre-diabetic state in mice com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b499989842d0b4f58d5bba63fbe9d1b
https://doi.org/10.1016/j.toxlet.2010.04.010

Cytokine-induced upregulation of NF-κB, IL-8, and ICAM-1 is dependent on colonic cell polarity: implication for PKCδ

Autor: Marie Pierre Montero, Claude Penel, Francis Fouchier, Sébastien Vallée, Serge Champion, Sullivan Laforest

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2004, 297 (1), pp.165-185. ⟨10.1016/j.yexcr.2004.03.007⟩
Experimental Cell Research, 2004, 297 (1), pp.165-185. ⟨10.1016/j.yexcr.2004.03.007⟩

As described for a long time, carcinoma-derived Caco-2 cells form a polarized epithelium in culture, whereas HT29-D4 cells are nonpolarized and undifferentiated but can form a polarized monolayer when cultured in a galactose-supplemented medium. Usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5b984a55e1adb03ffd7480387cb2c4
https://hal-amu.archives-ouvertes.fr/hal-03128106