Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Francis E. Baltasar"'
Autor:
Kenneth R. Dellamaggiore, Rachel Myerowitz, Audrey L. Fan, Meikana Lizadjohry, George A. Chernis, Christopher P. Ouellette, Elizabeth F. Neufeld, Cecilia D. Sedano, Francis E. Baltasar, Michelle Gonzales, Chi-hong B. Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 105:15908-15913
Enzyme replacement therapy for lysosomal storage diseases is currently based on endocytosis of lysosomal enzymes via the mannose or mannose 6-phosphate receptors. We are developing a technology for endocytosis of lysosomal enzymes that depends on gen
Autor:
Francis E. Baltasar, Daniel L. Cole, Jae-Taeg Hwang, Marc M. Greenberg, Chi-hong B. Chen, David S. Sigman
Publikováno v:
Bioorganicmedicinal chemistry. 11(10)
Inhibition of gene expression was recently achieved by targeting the transcriptionally competent open complex using relatively short, pentameric modified oligonucleotides at approximately 60 microM. Corroborative affinity cleavage experiments using t