Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Francis Doyle"'
Autor:
Nick St. John, Julian Freedland, Henri Baldino, Francis Doyle, Cinzia Cera, Thomas Begley, Michael Fasullo
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3929-3947 (2020)
Externí odkaz:
https://doaj.org/article/186adf76da6947818dcf54afdbfefa25
Autor:
Zachary Blalock, Daniel Lindqvist, Caroline Trumpff, Janine Flory, Jue Lin, Victor Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, SYSTEMS BIOLOGY PTSD BIOMARKERS CONSORTIUM SBPBC, Francis Doyle III, Charles Marmar, Marti Jett, Rachel Yehuda, Owen Wolkowitz, Synthia Mellon, Gwyneth Wu
Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or cellular stress and is a potential novel biomarker of psychological stress and of various brain, somatic, and psychiatric disorders. No studies have yet analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55984b2ba5598d785bfe388cc108b169
https://doi.org/10.21203/rs.3.rs-2838048/v1
https://doi.org/10.21203/rs.3.rs-2838048/v1
Heterocyclic aromatic amines (HAAs) are potent carcinogenic agents found in charred meats and cigarette smoke. However, few eukaryotic resistance genes have been identified. We usedSaccharomyces cerevisiae(budding yeast) to identify genes that confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceefd37e3f21ca7de60878fa7c8954fe
https://doi.org/10.1101/2022.10.26.513854
https://doi.org/10.1101/2022.10.26.513854
Autor:
Edward Eveleth, Zachary E. Wurz, Andreas B. Diendorfer, Susan T. Sharfstein, Francis Doyle, Matthew N. Henry, Scott A. Tenenbaum, Nicole Borth, Vandhana Muralidharan-Chari
Publikováno v:
J Biotechnol
Currently, stable Chinese hamster ovary cell lines producing therapeutic, recombinant proteins are established either by antibiotic and/or metabolic selection. Here, we report a novel technology, PTSelect™ that utilizes an siRNA cloned upstream of
Autor:
Seid Muhie, Gautam Gautam, Ruoting Yang, Burook Misganaw, Bernie Daigle, Synthia Mellon, Janine Flory, Duna Abu-Amara, Inyoul Lee, Kai Wang, PTSD Systems Biology Consortium, Leroy Hood, Rachel Yehuda, Charles Marmar, Owen Wolkowitz, Kerry J. Ressler, Francis Doyle III, Rasha Hammamieh, Marti Jett
Publikováno v:
SSRN Electronic Journal.
Autor:
Henri Baldino, Thomas J. Begley, Michael Fasullo, Nick St. John, Julian Freedland, Francis Doyle, Cinzia Cera
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 3929-3947 (2020)
Exposure to the mycotoxin aflatoxin B1 (AFB1) strongly correlates with hepatocellular carcinoma. P450 enzymes convert AFB1into a highly reactive epoxide that forms unstable 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 (AFB1-N7-Gua) DNA adducts, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44592764423cade7d4dba7011af35e33
https://doi.org/10.1101/629436
https://doi.org/10.1101/629436
Autor:
Scott A. Tenenbaum, Francis Doyle, Peter C. Dedon, Andrea Leonardi, Lauren Endres, Thomas J. Begley
Publikováno v:
PMC
The translation of mRNA in all forms of life uses a three-nucleotide codon and aminoacyl-tRNAs to synthesize a protein. There are 64 possible codons in the genetic code, with codons for the ∼20 amino acids and 3 stop codons having 1- to 6-fold dege
Autor:
Pamela J. Green, Dong-Hoon Jeong, Skye A. Schmidt, Scott A. Tenenbaum, Francis Doyle, Linda A. Rymarquis, Patricia L. Foley, Joel G. Belasco
Publikováno v:
Nucleic Acids Research
In metazoans, cleavage by the endoribonuclease SMG6 is often the first degradative event in non-sense-mediated mRNA decay (NMD). However, the exact sites of SMG6 cleavage have yet to be determined for any endogenous targets, and most evidence as to t
Autor:
Scott A. Tenenbaum, Blake C. Meyers, Francis Doyle, Zachary E. Wurz, Jeffrey L. Caplan, Kun Huang, Reza Hammond
Publikováno v:
Nucleic Acids Research
Small RNAs, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), play a variety of important regulatory roles in many eukaryotes. Their small size has made it challenging to study them directly in live cells. Here we describe an RNA-base