Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Francis Dominic Sanderson"'
Publikováno v:
Archives of Pharmacal Research. 35:579-593
Synthetic membranes are composed of thin sheets of polymeric macromolecules that can control the passage of components through them. Generally, synthetic membranes used in drug diffusion studies have one of two functions: skin simulation or quality c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68fb0152ff68cd1b18ce3658f1e397e
https://doi.org/10.1007/s12272-012-0401-7
https://doi.org/10.1007/s12272-012-0401-7
Autor:
David R. Witty, Jonathan Brand, Ho Y. Li, Paul Goldsmith, Michael Stott, Robert W. Ward, Jennifer Farge, Fiona Nimmo, Nicola Shuker, Sanjeet Singh Sehmi, Mathilde D’Angeli, Ian R. Kilford, Rio Hutchings, Jennifer Sweeting, Andrew K. Takle, John Skidmore, Hasmi Tajuddin, Michael A. Briggs, Giancarlo Trani, David Matthew Wilson, Francis Dominic Sanderson, Paula L. Nichols, David MacPherson, Stephen L. Garland, Ian D. Wall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1368-1372
A pharmacophore model was built, based on known CGRP receptor antagonists, and this was used to aid the identification of novel leads. Analogues were designed, modelled and synthesised which incorporated alternative 'LHS' fragments linked via either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3643131d8eb58a97f908780958aacc
https://doi.org/10.1016/j.bmcl.2010.01.012
https://doi.org/10.1016/j.bmcl.2010.01.012
Over the years, in vitro Franz diffusion experiments have evolved into one of the most important methods for researching transdermal drug administration. Unfortunately, this type of testing often yields permeation data that suffer from poor reproduci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d5765123ad5db4c84518d90ad78d8a
https://europepmc.org/articles/PMC2974154/
https://europepmc.org/articles/PMC2974154/
