Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study

Autor: Kaura, A, Hartley, A, Panoulas, V, Glampson, B, Shah, ASV, Davies, J, Mulla, A, Woods, K, Omigie, J, Shah, AD, Thursz, MR, Elliott, P, Hemmingway, H, Williams, B, Asselbergs, FW, O'Sullivan, M, Lord, GM, Trickey, A, Sterne, JA, Haskard, DO, Melikian, N, Francis, DP, Koenig, W, Shah, AM, Kharbanda, R, Perera, D, Patel, RS, Channon, KM, Mayet, J, Khamis, R

Publikováno v: Kaura, A, Hartley, A, Panoulas, V, Glampson, B, Shah, A S V, Davies, J, Mulla, A, Woods, K, Omigie, J, Shah, A D, Thursz, M R, Elliott, P, Hemmingway, H, Williams, B, Asselbergs, F W, O'Sullivan, M, Lord, G M, Trickey, A, Sterne, J A, Haskard, D O, Melikian, N, Francis, D P, Koenig, W, Shah, A M, Kharbanda, R, Perera, D, Patel, R S, Channon, K M, Mayet, J & Khamis, R 2022, ' Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome : A cohort study ', PLoS Medicine, vol. 19, no. 2, e1003911, pp. e1003911 . https://doi.org/10.1371/journal.pmed.1003911
Kaura, A, Hartley, A, Panoulas, V, Glampson, B, Shah, A S V, Davies, J, Mulla, A, Woods, K, Omigie, J, Shah, A D, Thursz, M R, Elliott, P, Hemmingway, H, Williams, B, Asselbergs, F W, O'Sullivan, M, Lord, G M, Trickey, A, Sterne, J A, Haskard, D O, Melikian, N, Francis, D P, Koenig, W, Shah, A M, Kharbanda, R, Perera, D, Patel, R S, Channon, K M, Mayet, J & Khamis, R 2022, ' Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome : A cohort study ', PLoS Medicine, vol. 19, no. 2, e1003911 . https://doi.org/10.1371/journal.pmed.1003911

Funder: THIS Institute
BACKGROUND: There is limited evidence on the use of high-sensitivity C-reactive protein (hsCRP) as a biomarker for selecting patients for advanced cardiovascular (CV) therapies in the modern era. The prognostic value of mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82915bcff7d946b431b5f0a8b89d2ac4
https://www.repository.cam.ac.uk/handle/1810/335410

Non-invasive detection of exercise-induced cardiac conduction abnormalities in sudden cardiac death survivors in the inherited cardiac conditions

Autor: Leong, KMW, Ng, FS, Shun-Shin, MJ, Koa-Wing, M, Qureshi, N, Whinnett, ZI, Linton, NF, Lefroy, D, Francis, DP, Harding, SE, Davies, DW, Peter, NS, Lim, PB, Behr, E, Lambiase, PD, Varnava, A, Kanagaratnam, P

AIMS : Rate adaptation of the action potential ensures spatial heterogeneities in conduction across the myocardium are minimized at different heart rates providing a protective mechanism against ventricular fibrillation (VF) and sudden cardiac death

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::aeb8cb79e9568c58456c62a3edce1d43

Mechanisms of Myocardial Ischemia in Hypertrophic Cardiomyopathy

Autor: Raphael, CE, Cooper, R, Parker, KH, Collinson, J, Vassiliou, V, Pennell, DJ, De Silva, R, Hsu, LY, Greve, AM, Nijjer, S, Broyd, C, Ali, A, Keegan, J, Francis, DP, Davies, JE, Hughes, AD, Arai, A, Frenneaux, M, Stables, RH, Di Mario, C, Prasad, SK

Publikováno v: Journal of the American College of Cardiology

BACKGROUND: Angina is common in hypertrophic cardiomyopathy (HCM) and is associated with abnormal myocardial perfusion. Wave intensity analysis improves the understanding of the mechanics of myocardial ischemia. OBJECTIVES: Wave intensity analysis wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::90b6e1e7f25ae5943eee2bcc4cfc2b20

Moving the goalposts into unblinded territory: lessons of DEFER and FAME 2 and their implications for shifting end points in ISCHEMIA

Autor: Rajkumar, CA, Nijjer, SS, Cole, GD, Al-Lamee, R, Francis, DP

At its conception, a randomized controlled trial is carefully designed to detect a significant effect of an intervention on a prespecified primary end point. Each aspect of a trial is deliberately constructed to allow it to answer this principal ques

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::d315a655cf0a89775f8fb90110b00f9f
http://hdl.handle.net/10044/1/63852

Results of a physician survey on ordering viral load testing: opportunity for laboratory consultation.

Autor: Hofherr LK (AUTHOR), Francis DP (AUTHOR), Astles JR (AUTHOR), Schalla WO (AUTHOR)

Publikováno v: Archives of Pathology & Laboratory Medicine. Apr2003, Vol. 127 Issue 4, p446-450. 5p.