Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Francis Combes"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-8 (2024)
Production and storage of synthetic mRNA can introduce a variety of byproducts which reduce the overall integrity and functionality of mRNA vaccines and therapeutics. mRNA integrity is therefore designated as a critical quality attribute which must b
Externí odkaz:
https://doaj.org/article/35a9f18a99204cc880a0c631d0e17b3a
Autor:
Hanne Huysmans, Joyca De Temmerman, Zifu Zhong, Séan Mc Cafferty, Francis Combes, Freddy Haesebrouck, Niek N. Sanders
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 388-395 (2019)
Local administration of naked self-replicating mRNA (sr-mRNA) in the skin or muscle using electroporation is effective but hampered by low repeatability. In this manuscript, we demonstrated that intradermal electroporation of sr-mRNA in combination w
Externí odkaz:
https://doaj.org/article/69173e535c7246c3894863d2ba005485
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 848-856 (2018)
Solid tumors frequently coexist with a degree of local chronic inflammation. Recruited myeloid cells can therefore be considered as interesting vehicles for tumor-targeted delivery of therapeutic agents. Using in vivo imaging, the short-term accumula
Externí odkaz:
https://doaj.org/article/409d86e901374973a97675bbe2cdb401
Akademický článek
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Autor:
Francis Combes
Publikováno v:
La Pensée. :7-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5167742711e69ae610d58b31876ad142
https://doi.org/10.3917/lp.410.0007
https://doi.org/10.3917/lp.410.0007
Autor:
Christian Czysch, Carolina Medina‐Montano, Zifu Zhong, Alexander Fuchs, Judith Stickdorn, Pia Winterwerber, Sascha Schmitt, Kim Deswarte, Marco Raabe, Maximilian Scherger, Francis Combes, Jana De Vrieze, Sabah Kasmi, Niek N. Sandners, Stefan Lienenklaus, Kaloian Koynov, Hans‐Joachim Räder, Bart N. Lambrecht, Sunil A. David, Matthias Bros, Hansjörg Schild, Stephan Grabbe, Bruno G. De Geest, Lutz Nuhn
Publikováno v:
Advanced Functional Materials, 32(35):2203490. Wiley-VCH
Advanced Functional Materials
Advanced Functional Materials
The development of controlled biodegradable materials is of fundamental importance in immunodrug delivery to spatiotemporally controlled immune stimulation but avoid systemic inflammatory side effects. Based on this, polycarbonate nanogels are develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acfb5007876972a84ea63a6bb0c2a2e
https://pure.eur.nl/en/publications/c2730e7e-773c-40fe-a341-123d74664982
https://pure.eur.nl/en/publications/c2730e7e-773c-40fe-a341-123d74664982
Autor:
Lisa Opsomer, Haixiu Wang, Stefan Lienenklaus, Francis Combes, Zifu Zhong, Niek N. Sanders, João Paulo Portela Catani, Joyca De Temmerman, Séan McCafferty, Hanne Huysmans
Publikováno v:
Molecular Therapy
Synthetic mRNAs are an appealing platform with multiple biomedical applications ranging from protein replacement therapy to vaccination. In comparison with conventional mRNA, synthetic self-amplifying mRNAs (sa-mRNAs) are gaining interest because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef58b6fc1e72a9d8203ff7756be8253
https://doi.org/10.1016/j.ymthe.2021.01.023
https://doi.org/10.1016/j.ymthe.2021.01.023
Autor:
Séan Mc Cafferty, Darrell J. Irvine, Tasuku Kitada, Jacob R. Becraft, Niek N. Sanders, Ron Weiss, Francis Combes, Mathias Devreese, Joyca De Temmerman, Siegrid De Baere
Publikováno v:
Mol Ther
Synthetic mRNA therapeutics have the potential to revolutionize healthcare, as they enable patients to produce therapeutic proteins inside their own bodies. However, convenient methods that allow external control over the timing and magnitude of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25edd2a77eaf2a9d20e68ce58f9533aa
https://doi.org/10.1016/j.ymthe.2020.11.010
https://doi.org/10.1016/j.ymthe.2020.11.010
Autor:
Patricia Latour, Francis Combes
Publikováno v:
La Pensée. :5-17
a partir du constat que Marcel Cohen faisait de l’evolution du francais, dans les annees soixante (dans son livre Histoire d’une langue, le francais), les auteurs examinent ce qui reste constant dans la pratique du francais courant, ce qui contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a05d7e783ecef14547e6aee1b4c0060
https://doi.org/10.3917/lp.403.0005
https://doi.org/10.3917/lp.403.0005
Autor:
Yongjun Liu, Zifu Zhong, Simon Van Herck, Lutz Nuhn, Bruno G. De Geest, Niek N. Sanders, Francis Combes, Stefan Lienenklaus, Stefaan De Koker, Sunil A. David, Xiaochu Ding, Yadong Wang, Hui Li, Yanyun Hao, Zhiyue Zhang
Publikováno v:
ACS BIOMATERIALS SCIENCE & ENGINEERING
Strategies that can reduce the harmful side effects of potent immunomodulatory drugs are in high demand to facilitate clinical translation of the newest generation of immunotherapy. Indeed, uncontrolled triggering of the immune system can lead to lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c5c6b99d33f015a07dd3d03f0827cd
https://doi.org/10.1021/acsbiomaterials.0c00485
https://doi.org/10.1021/acsbiomaterials.0c00485