Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Francis Bonnefoy"'
Autor:
Thierry Gauthier, Omayra Martin-Rodriguez, Cécile Chagué, Anna Daoui, Adam Ceroi, Alexis Varin, Francis Bonnefoy, Séverine Valmary-Degano, Mélanie Couturier, Susanne Behlke, Philippe Saas, Pierre-François Cartron, Sylvain Perruche
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Reinstating inflammation resolution represents an innovative concept to regain inflammation control in diseases marked by chronic inflammation. While most therapeutics target inflammatory molecules and inflammatory effector cells
Externí odkaz:
https://doaj.org/article/ff55f83d61f749b3983efca034044231
Autor:
Patricia Mercier-Letondal, Abhishek Kumar, Chrystel Marton, Francis Bonnefoy, Maxime Fredon, Laura Boullerot, Barbara Dehecq, Olivier Adotévi, Yann Godet, Jeanne Galaine
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Engineered T cell-based adoptive immunotherapies met promising success for the treatment of hematological malignancies. Nevertheless, major hurdles remain to be overcome regarding the management of relapses and the translation to solid tumor settings
Externí odkaz:
https://doaj.org/article/47c72de19c5b40c2b6c2e75433a338fb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Several chronic inflammatory diseases are associated with non-resolving inflammation. Conventional anti-inflammatory drugs fail to completely cure these diseases. Resolution pharmacology is a new therapeutic approach based on the use of pro-resolving
Externí odkaz:
https://doaj.org/article/49d134566c0441a98be7714a2fec9ded
Autor:
Margaux Poussard, Laure Philippe, Maxime Fredon, Elodie Bôle‐Richard, Sabeha Biichle, Florian Renosi, Sophie Perrin, Marie Kroemer, Samuel Limat, Francis Bonnefoy, Etienne Daguindau, Eric Deconinck, Bérengère Gruson, Philippe Saas, Olivier Adotévi, Francine Garnache‐Ottou, Fanny Angelot‐Delettre
Publikováno v:
eJHaem, Vol 2, Iss 1, Pp 125-130 (2021)
Abstract Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with poor prognosis and no treatment consensus. Combining chemotherapy and immunotherapy is a promising strategy to enhance therapeutic effect. Before co
Externí odkaz:
https://doaj.org/article/3786b6a3b47b4c46940e845d3bc1b435
Autor:
Audrey Wetzel, Francis Bonnefoy, Cécile Chagué, Mathieu Vetter, Mélanie Couturier, Blandine Baffert, Olivier Adotévi, Philippe Saas, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Cancers are consequences of cellular dysfunction leading to an aberrant cellular multiplication and proliferation, subsequently yielding metastasis formation. Inflammatory reaction, with immune cell recruitment, is the main defense against precancero
Externí odkaz:
https://doaj.org/article/0fbbf3ab40294c698513f236f819d73b
Autor:
Omayra Martin-Rodriguez, Thierry Gauthier, Francis Bonnefoy, Mélanie Couturier, Anna Daoui, Cécile Chagué, Séverine Valmary-Degano, Claire Gay, Philippe Saas, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Nonresolving inflammation is a critical driver of several chronic inflammatory diseases, including inflammatory bowel diseases (IBD). This unresolved inflammation may result from the persistence of an initiating stimulus or from the alteration of the
Externí odkaz:
https://doaj.org/article/0aceeb52c9d44511b1067adf0daf7a7d
Autor:
Florence Marliot, Marc Van den Eynde, Franck Pagès, Romain Boidot, Céline Mirjolet, Amos Kirilovsky, Carine El Sissy, Nacilla Haicheur-Adjouri, Viorel Scripcariu, Olivier Adotevi, Laurie Spehner, Elodie Lauret Marie Joseph, Benoît Lecoester, Laura Boullerot, Laurie Rangan, Amélie Marguier, Florent Tochet, Magalie Dosset, Jihane Boustani, Patrice Ravel, Jean-René Pallandre, Francis Bonnefoy, Emmanuel Cornillot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Multiple synergistic combination approaches with cancer drugs are developed to overcome primary resistance to immunotherapy; however, the mechanistic rationale to combine chemoradiotherapy (CRT) with immune checkpoint inhibitors remains el
Externí odkaz:
https://doaj.org/article/2c4df4d5a35b4af1b8a7572b3ea26484
Autor:
Céline Coppard, Francis Bonnefoy, Dalil Hannani, Françoise Gabert, Olivier Manches, Joel Plumas, Sylvain Perruche, Laurence Chaperot
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Despite major advances in rheumatoid arthritis outcome, not all patients achieve remission, and there is still an unmet need for new therapeutic approaches. This study aimed at evaluating in a pre-clinical murine model the efficac
Externí odkaz:
https://doaj.org/article/3a25a8eec97c49d0b2f3120b20cdd405
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rheumatoid arthritis (RA) is a chronic immune-mediated disease managed by conventional synthetic drugs, such as methotrexate (MTX), and targeted drugs including biological agents. Cell-based therapeutic approaches are currently developed in RA, mainl
Externí odkaz:
https://doaj.org/article/c67d15b7e56443b79d05fe3dacd7de5e
Autor:
Francis Bonnefoy, Thierry Gauthier, Romain Vallion, Omayra Martin-Rodriguez, Anais Missey, Anna Daoui, Séverine Valmary-Degano, Philippe Saas, Mélanie Couturier, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Unresolved inflammation is a common feature in the pathogenesis of chronic inflammatory/autoimmune diseases. The factors produced by macrophages eliminating apoptotic cells during resolution are crucial to terminate inflammation, and for subsequent t
Externí odkaz:
https://doaj.org/article/be799b3bb92044b480c1aadd98c26651