Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Francis Aguisanda"'
Autor:
Francis Aguisanda, Charles D. Yeh, Catherine Z. Chen, Rong Li, Jeanette Beers, Jizhong Zou, Natasha Thorne, Wei Zheng
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-13 (2017)
Abstract Background Wolman disease (WD) is a rare lysosomal storage disorder that is caused by mutations in the LIPA gene encoding lysosomal acid lipase (LAL). Deficiency in LAL function causes accumulation of cholesteryl esters and triglycerides in
Externí odkaz:
https://doaj.org/article/25d0521044da4cb0a2c485727e6d6954
Autor:
Jeanette Beers, Francis Aguisanda, Rong Li, Jizhong Zou, Catherine Z. Chen, Wei Zheng, Natasha Thorne, Charles D. Yeh
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-13 (2017)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Background Wolman disease (WD) is a rare lysosomal storage disorder that is caused by mutations in the LIPA gene encoding lysosomal acid lipase (LAL). Deficiency in LAL function causes accumulation of cholesteryl esters and triglycerides in lysosomes
Publikováno v:
Current Chemical Genomics and Translational Medicine
Wolman disease (WD) and cholesteryl ester storage disease (CESD) are lysosomal storage diseases (LSDs) caused by a deficiency in lysosomal acid lipase (LAL) due to mutations in the LIPA gene. This enzyme is critical to the proper degradation of chole
Autor:
Noel Southall, Jean Zhao, Natasha Thorne, Bradley Class, Wei Zheng, John C. McKew, Menghang Xia, Francis Aguisanda, Nasir Malik, Mahendra S. Rao, Sonia Shah
Publikováno v:
Stem Cells Translational Medicine
Using astrocytes differentiated from human embryonic stem cells, an assay was developed to identify compounds that protect against oxidative stress, a condition associated with many neurodegenerative diseases. The assay has been optimized for high-th
Autor:
Catriona Y. Logan, Adrián Álvarez-Varela, Francis Aguisanda, Bruce Wang, Bin Li, Markus Grompe, Teni Anbarchian, Roel Nusse, Yinhua Jin, Matt Fish, Junjie Zhu, Weng Chuan Peng, Peng Wu
Publikováno v:
Cell, vol 175, iss 6
In the healthy adult liver, most hepatocytes proliferate minimally. However, upon physical or chemical injury to the liver, hepatocytes proliferate extensively invivo under the direction of multiple extracellular cues, including Wnt and pro-inflammat
Autor:
Francis Aguisanda, Panagiota Kitsantas
Publikováno v:
Journal of Asthma. 53:25-29
The purpose of this study was to examine the association between asthma diagnosis and obesity among adolescents exposed to environmental tobacco smoke (ETS).The sample included 28,807 adolescents (13-17 years old) from the National Survey of Children
Publikováno v:
SLAS Technology. 20:164-174
Cell viability assays are extensively used to determine cell health, evaluate growth conditions, and assess compound cytotoxicity. Most existing assays are endpoint assays, in which data are collected at one time point after termination of the experi
Autor:
Francis Aguisanda
Publikováno v:
Science. 362:1078-1078
I never thought my mom's first tour of Stanford University would be of the psychiatric ward. When I arrived in sunny California 2 years earlier to start my Ph.D. studies, I was on top of the world. But that feeling of triumph vanished quickly. The un
Autor:
Aguisanda F; Francis Aguisanda is a Ph.D. student at Stanford University in Palo Alto, California, and a crisis counselor for the U.S. National Suicide Prevention Lifeline (1-800-273-8255). Send your career story to SciCareerEditor@aaas.org.
Publikováno v:
Science (New York, N.Y.) [Science] 2018 Nov 30; Vol. 362 (6418), pp. 1078.