Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression

Autor: Timothy I. Shaw, Jessica Wagner, Liqing Tian, Elizabeth Wickman, Suresh Poudel, Jian Wang, Robin Paul, Selene C. Koo, Meifen Lu, Heather Sheppard, Yiping Fan, Francis H. O’Neill, Ching C. Lau, Xin Zhou, Jinghui Zhang, Stephen Gottschalk

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract Immunotherapy with chimeric antigen receptor T cells for pediatric solid and brain tumors is constrained by available targetable antigens. Cancer-specific exons present a promising reservoir of targets; however, these have not been explored

Externí odkaz: https://doaj.org/article/a7f623660f4c451a9230c9fee62ee7a1

A new role for spinal manual therapy and for chiropractic? Part I: weaknesses and threats

Autor: Søren Francis Dyhrberg O’Neill, Casper Nim, Dave Newell, Charlotte Leboeuf-Yde

Publikováno v: Chiropractic & Manual Therapies, Vol 32, Iss 1, Pp 1-8 (2024)

Abstract Spinal manual therapy is central to chiropractic history, clinical practice, and professional identity. That chiropractors have developed an expertise in this domain has provided some considerable advantages. However, we contend it is also a

Externí odkaz: https://doaj.org/article/c2eb89f70f8244d0ab3c6cc418eff688

Automated Mapping of Land Cover Type within International Heterogenous Landscapes Using Sentinel-2 Imagery with Ancillary Geospatial Data

Autor: Kristofer Lasko, Francis D. O’Neill, Elena Sava

Publikováno v: Sensors, Vol 24, Iss 5, p 1587 (2024)

A near-global framework for automated training data generation and land cover classification using shallow machine learning with low-density time series imagery does not exist. This study presents a methodology to map nine-class, six-class, and five-

Externí odkaz: https://doaj.org/article/1cecc3b8c88c4cec98abb93297016e69

The association between sociodemographic characteristics and the event of undergoing first-time, simple lumbar discectomy: A case-control study

Autor: Dorthe Schoeler Ziegler, Clara Emilie Westermann, Ann Fredsted Aalling, Soeren Francis Dyhrberg O'Neill, Mikkel Oesterheden Andersen

Publikováno v: North American Spine Society Journal, Vol 9, Iss , Pp 100106- (2022)

Background: In disc herniation, nonsurgical treatments are recommended prior to elective discectomy but are often associated with consultation fees, whereas the discectomy itself may be without user payment. This may affect individual preferences in

Externí odkaz: https://doaj.org/article/031fee8389004efa894a8a52f099282a

A simple, bed-side tool to assess evoked pressure pain intensity

Autor: Søren Nicolai Frederiksen Hostrup, Søren Francis Dyhrberg O’Neill, Jesper Bie Larsen, Lars Arendt-Nielsen, Kristian Kjær Petersen

Publikováno v: Hostrup, S N F, O'Neill, S F D, Larsen, J B, Arendt-Nielsen, L & Petersen, K K 2023, ' A simple, bed-side tool to assess evoked pressure pain intensity ', Scandinavian Journal of Pain, vol. 23, no. 2, pp. 382-388 . https://doi.org/10.1515/sjpain-2022-0055

Objectives Existing equipment for quantitative sensory testing is generally expensive and not easily applicable in a clinical setting thus simple bed-side devices are warranted. Pressure hyperalgesia is a common finding in patients with musculoskelet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d763eb16aab4664b798f509e364a1fb0
https://vbn.aau.dk/da/publications/d3a4818c-656f-4bbf-8947-2cd015ed5851