Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Francis J. Koszyk"'
Autor:
Yu Yi, Jacquelen J. Casler, Peter C. Isakson, Jaime L. Masferrer, Ish K. Khanna, Francis J. Koszyk, Paul W. Collins, Karen Seibert, Richard M. Weier, Yan Zhang, A. W. Veenhuizen, Carol M. Koboldt, Xiangdong Xu, William E. Perkins, S. A. Gregory
Publikováno v:
Journal of Medicinal Chemistry. 40:1634-1647
Series of 1,2-diarylimidazoles has been synthesized and found to contain highly potent and selective inhibitors of the human COX-2 enzyme. The paper describes a short synthesis of the target 1,2-diarylimidazoles starting with aryl nitriles. Different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93724e239a9064506c442ec529d65fd
https://doi.org/10.1021/jm9700225
https://doi.org/10.1021/jm9700225
Autor:
Shashidhar N. Rao, Francis J. Koszyk, Ish K. Khanna, Decrescenzo Gary A, Getman Daniel P, Janet Anne Julien, Richard M. Weier, Stealey Michael A, Heintz Robert M, Richard A. Mueller, Lydia Swenton
Publikováno v:
Journal of Carbohydrate Chemistry. 14:843-878
A useful methodology for the synthesis of a number of 2-, 3- and 2,3-disubstituted deoxynojirimycin analogs is reported. It has been found that the epoxides in stereoselectively synthesized N-carboalkoxy-2,3-anhydro-1-deoxymannojirimycins (4 and 5) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97befdaa53d580da61e6afa663f24b01
https://doi.org/10.1080/07328309508005380
https://doi.org/10.1080/07328309508005380
Autor:
Francis J. Koszyk, Peter C. Isakson, Ish K. Khanna, Karen Seibert, Yu Yi, S. A. Gregory, William E. Perkins, Yan Zhang, Jaime L. Masferrer, Paul W. Collins, Jacquelen J. Casler, Richard M. Weier, A. W. Veenhuizen, Carol M. Koboldt, Xiangdong Xu
Publikováno v:
ChemInform. 28
Series of 1,2-diarylimidazoles has been synthesized and found to contain highly potent and selective inhibitors of the human COX-2 enzyme. The paper describes a short synthesis of the target 1,2-diarylimidazoles starting with aryl nitriles. Different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec0980e981c6b888c3d02a940605cf8
https://doi.org/10.1002/chin.199739142
https://doi.org/10.1002/chin.199739142
Autor:
Matthew J. Graneto, Ravi G. Kurumbail, Michael L. Vazquez, Huey-Sheng Shieh, Jennifer L. Pawlitz, Jennifer M. Williams, William C. Stallings, Lifeng Geng, Ashok S. Naraian, Francis J. Koszyk, Michael A. Stealey, Xiangdong D. Xu, Richard M. Weier, Gunnar J. Hanson, Robert J. Mourey, Robert P. Compton, Stephen J. Mnich, Gary D. Anderson, Joseph B. Monahan, Rajesh Devraj
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 23, p5712-5719, 8p
Publikováno v:
The Journal of Organic Chemistry. 46:2911-2915
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4612e669a0a3744874610ca88fa9c12
https://doi.org/10.1021/jo00327a014
https://doi.org/10.1021/jo00327a014
Publikováno v:
The Journal of Organic Chemistry. 48:3581-3583
Synthese soit par cycloaddition intramoleculaire de la diazo-2 nonadiene-6,8one-3, soit a partir d'une cyclopenta [c] furannone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd9bcdf7c79b1ffc08be342d047b6243
https://doi.org/10.1021/jo00168a050
https://doi.org/10.1021/jo00168a050
Autor:
George R. Lenz, Francis J. Koszyk
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1273
A biomimetically patterned synthesis of the novel oxazine-fused dehydronoraporphine alkaloid, duguenaine, which proceeds in three steps from an isoquinoline enamide has been developed. The reactions leading to the natural product are general and yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792fe0dfbc9a311e75b9320d24405d06
https://doi.org/10.1039/p19840001273
https://doi.org/10.1039/p19840001273