Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation.

Autor: Jean-Marie Launay, Muriel Del Pino, Gilles Chironi, Jacques Callebert, Katell Peoc'h, Jean-Louis Mégnien, Jacques Mallet, Alain Simon, Francine Rendu

Publikováno v: PLoS ONE, Vol 4, Iss 11, p e7959 (2009)

BackgroundPostulating that serotonin (5-HT), released from smoking-activated platelets could be involved in smoking-induced vascular modifications, we studied its catabolism in a series of 115 men distributed as current smokers (S), never smokers (NS

Externí odkaz: https://doaj.org/article/560f48c518334ac7bb46feb320e0217d

Dehydration of blood platelets by zeodration: in vitro characterization and hemostatic properties in vivo

Autor: Francine Rendu, Catherine Ravanat, Eric Maurer, Monique Freund, Anita Eckly, Christian Gachet, Ghina Alame, J.-P. Cazenave, Pierre Mangin, Catherine Ziessel, Thibault Donnet

Publikováno v: Transfusion. 55:2207-2218

BACKGROUND Platelets (PLTs) are currently stored at room temperature (RT) for 5 to 7 days. So far, there exists no validated method for the preparation and long-term storage of dehydrated PLTs suitable for transfusion after rehydration. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ce08429a46df34c9133edb7940265bf
https://doi.org/10.1111/trf.13121

Endothelial cell markers' kinetics following umbilical cord blood transplantation

Autor: Jean-Pierre Marie, Anna D. Petropoulou, Samama M, Francine Rendu, Pezhman Mirshahi, Bernard Rio, Jeannette Soria, Ismail Elalamy

Publikováno v: Leukemia & lymphoma
Leukemia & lymphoma, 2008, 49 (11), pp.2209-2212. ⟨10.1080/10428190802322901⟩
Leukemia & lymphoma, Taylor & Francis, 2008, 49 (11), pp.2209-2212. ⟨10.1080/10428190802322901⟩
Leukemia & lymphoma, Taylor & Francis, 2008, 49 (11), pp.2209-2212. 〈10.1080/10428190802322901〉

Hyper acute and acute vascular rejections represent the major problem in organ xeno-transplantation. According to the humoral theory of transplantation, acute and chronic rejections of allografts a...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd311623c206b679e304669d2e40dd91
https://doi.org/10.1080/10428190802322901

Homocysteine induces oxidative stress by uncoupling of no synthase activity through reduction of tetrahydrobiopterin

Autor: Gokce Topal, Elisabeth Millanvoye, Francine Rendu, Jean-Luc Boucher, Marie-Aude Devynck, Annie Brunet, Monique David-Dufilho

Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2004, 36 (12), pp.1532-1541. ⟨10.1016/j.freeradbiomed.2004.03.019⟩

Hyperhomocysteinemia is a risk factor for cardiovascular diseases that induces endothelial dysfunction. Here, we examine the participation of endothelial NO synthase (eNOS) in the homocysteine-induced alterations of NO/O(2)(-) balance in endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c1a698e0bd671ed91c8e053acd6022
https://doi.org/10.1016/j.freeradbiomed.2004.03.019

Platelet αIIb-β3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk

Autor: Francine Rendu, Christilla Bachelot-Loza, Abdelhafid Saci

Publikováno v: Biochemical Journal. 351:669-676

Agonist-induced platelet activation triggers 'inside-out' signalling which activates alpha IIb-beta 3, the most abundant integrin in platelet membranes. The engagement of activated alpha IIb-beta 3 integrin by linking fibrinogen is necessary for plat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::038ef69f8f5d7cd40e3a20501193e2c3
https://doi.org/10.1042/bj3510669