Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Francine M, Jodelka"'
Autor:
Joanna A. Korecka, Sebastien Talbot, Teresia M. Osborn, Sherida M. de Leeuw, Simon A. Levy, Eliza J. Ferrari, Alyssa Moskites, Elise Atkinson, Francine M. Jodelka, Anthony J. Hinrich, Michelle L. Hastings, Clifford J. Woolf, Penelope J. Hallett, Ole Isacson
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 29-41 (2019)
Summary: The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD patients at postmortem. Human induced pluripotent stem cell (iPSC)-derived neurons with the PD pathogenic LRRK2 G2019S m
Externí odkaz:
https://doaj.org/article/872a0bc4898b44ba96fb040e2470c7bb
Autor:
Ashley A Blackwell, Francine M Jodelka, Rami I. Lake, Michelle L. Hastings, Douglas G. Wallace
Publikováno v:
Neuroscience. 511:53-69
Alzheimer's disease (AD) is associated with hippocampal neuropathology and cognitive impairments, including wandering behavior or becoming lost in a familiar environment. Wandering behavior is severe and manifests early in life for people with specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a21bd119d6bf01484476838afb2277
https://doi.org/10.1016/j.neuroscience.2022.12.012
https://doi.org/10.1016/j.neuroscience.2022.12.012
Supplementary Figure 4 from BRCA1 Promotes Induction of ssDNA by Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc84800db877ae2b63db7e8dd8995b5
https://doi.org/10.1158/0008-5472.22365362.v1
https://doi.org/10.1158/0008-5472.22365362.v1
Supplementary Figure 1 from BRCA1 Promotes Induction of ssDNA by Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303b6ffbf772183c3342a70a894f15b9
https://doi.org/10.1158/0008-5472.22365371
https://doi.org/10.1158/0008-5472.22365371
Supplementary Figure 3 from BRCA1 Promotes Induction of ssDNA by Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43616a189adaf65833073d0770b778f4
https://doi.org/10.1158/0008-5472.22365365
https://doi.org/10.1158/0008-5472.22365365
The BRCA1 tumor suppressor contributes to the repair of DNA double-strand breaks (DSB) through homologous recombination, but the mechanism is unknown. The rapid accumulation of BRCA1 into nuclear foci in response to induction of DNA breaks suggests t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c06cdcb78982f4763a1ccf32b4472
https://doi.org/10.1158/0008-5472.c.6494666
https://doi.org/10.1158/0008-5472.c.6494666
Supplementary Figure 2 from BRCA1 Promotes Induction of ssDNA by Ionizing Radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db18a95a54450553479a1d13eed8729a
https://doi.org/10.1158/0008-5472.22365368.v1
https://doi.org/10.1158/0008-5472.22365368.v1
Autor:
Anthony J Hinrich, Francine M Jodelka, Jennifer L Chang, Daniella Brutman, Angela M Bruno, Clark A Briggs, Bryan D James, Grace E Stutzmann, David A Bennett, Steven A Miller, Frank Rigo, Robert A Marr, Michelle L Hastings
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 4, Pp 328-345 (2016)
Abstract Apolipoprotein E receptor 2 (ApoER2) is an apolipoprotein E receptor involved in long‐term potentiation, learning, and memory. Given its role in cognition and its association with the Alzheimer's disease (AD) risk gene, apoE, ApoER2 has be
Externí odkaz:
https://doaj.org/article/53d79b4ef2ba4429a49c1630f225c643
Autor:
Jessica L. Centa, Frank Rigo, Francine M. Jodelka, Anthony J. Hinrich, Joseph Ochaba, Dominik M. Duelli, Michaela Jackson, Tyler B. Johnson, Jill M. Weimer, Michelle L. Hastings
Publikováno v:
Nat Med
CLN3 Batten disease is an autosomal recessive, neurodegenerative, lysosomal storage disease caused by mutations in CLN3, which encodes a lysosomal membrane protein(1–3). There are no disease-modifying treatments for this disease that affects up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691da9b29531e7c892f5b7b4a35daddf
https://doi.org/10.1038/s41591-020-0986-1
https://doi.org/10.1038/s41591-020-0986-1
Autor:
Stephanie A. Carmack, Janaina C. M. Vendruscolo, M. Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D. Bosse, Daniele Mercatelli, Federico M. Giorgi, Yu Fu, Anthony J. Hinrich, Francine M. Jodelka, Karen Ling, Robert O. Messing, Randall T. Peterson, Frank Rigo, Scott Edwards, Pietro P. Sanna, Marisela Morales, Michelle L. Hastings, George F. Koob, Leandro F. Vendruscolo
Publikováno v:
Molecular psychiatry. 27(5)
The global crisis of opioid overdose fatalities has led to an urgent search to discover the neurobiological mechanisms of opioid use disorder (OUD). A driving force for OUD is the dysphoric and emotionally painful state (hyperkatifeia) that is produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fefad6c9723346ce90142d40373ffa8
https://pubmed.ncbi.nlm.nih.gov/35296810
https://pubmed.ncbi.nlm.nih.gov/35296810