Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Francine H Einstein"'
Autor:
Radhika H Muzumdar, Derek M Huffman, Gil Atzmon, Christoph Buettner, Laura J Cobb, Sigal Fishman, Temuri Budagov, Lingguang Cui, Francine H Einstein, Aruna Poduval, David Hwang, Nir Barzilai, Pinchas Cohen
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6334 (2009)
Decline in insulin action is a metabolic feature of aging and is involved in the development of age-related diseases including Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD). A novel mitochondria-associated peptide, Humanin (HN), has a
Externí odkaz:
https://doaj.org/article/3f99404b30f64a889176582ce9cc202c
Autor:
Jessica Tozour, Hye Heo, Lingguang Cui, Fabien Delahaye, Francine H. Einstein, Yongmei Zhao, Nir Barzilai
Publikováno v:
Aging Cell
Summary Adverse environmental exposures of mothers during fetal period predispose offspring to a range of age-related diseases earlier in life. Here, we set to determine whether a deregulated epigenetic pattern is similar in young animals whose mothe
Autor:
Lyda Williams, Francine H. Einstein, Maureen J. Charron, Yoshinori Seki, Fabien Delahaye, Alex Cheng, Mamta Fuloria
Publikováno v:
Diabetologia. 59:1714-1723
Intrauterine growth restriction (IUGR) is associated with increased susceptibility to obesity, metabolic syndrome and type 2 diabetes. Although the mechanisms underlying the developmental origins of metabolic disease are poorly understood, evidence s
Autor:
Hye Heo, Temuri Budagov, Asher Bashiri, Moshe Mazor, Francine H. Einstein, Gil Atzmon, Danny Ben-Avraham
Publikováno v:
Molecular Genetics and Genomics. 289:695-705
Maternal obesity is a significant risk factor for development of both maternal and fetal metabolic complications. Increase in visceral fat and insulin resistance is a metabolic hallmark of pregnancy, yet little is known how obesity alters adipose cel
Autor:
Francis I. Baffour, Kathryn F. Kirchoff-Torres, Francine H. Einstein, Scarlett Karakash, Todd S. Miller
Publikováno v:
Obstetrics & Gynecology. 119:489-492
Bilateral internal carotid artery dissection is a rare event associated with pregnancy, especially in a patient without any predisposing risk factors.A 34-year-old woman presented with postpartum unilateral weakness, headaches, and blurry vision 14 d
Autor:
Zamir Halpern, Francine H. Einstein, Sigal Fishman, Amir Shlomai, Shani Ben-Shlomo, Isabel Zvibel, Nir Barzilai, Dikla Atias
Publikováno v:
Obesity. 20:151-156
The present study examined whether the perinephric and epididymal visceral fat (PEVF) depot under short-term excess nutrient protected the liver by trapping nutrient-derived nonesterified free fatty acids (NEFAs) or had deleterious effects on hepatic
Autor:
Francine H Einstein, Scarlett Karakash
Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 18:99-103
Purpose of review Little consensus exists on the definition of gestational diabetes (GDM), how the condition should be diagnosed, and if interventions for mild maternal hyperglycemia are of any benefit to the mother or fetus. Today, after several lar
Autor:
Francine H. Einstein, Reid F. Thompson
Publikováno v:
Journal of Women's Health. 19:581-587
The current concept of fetal origins of adult diseases describes in utero programming, or adaptation to a spectrum of adverse environmental conditions that ultimately leads to increased susceptibility to age-related diseases (e.g., type 2 diabetes an
Autor:
Radhika Muzumdar, Hui Chen, Francine H. Einstein, Ranganath Muniyappa, Xu Yan, Lilly Q. Yue, Nir Barzilai, Michael J. Quon
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E1023-E1029
Assessing insulin resistance in rodent models gives insight into mechanisms that cause type 2 diabetes and the metabolic syndrome. The hyperinsulinemic euglycemic glucose clamp, the reference standard for measuring insulin sensitivity in humans and a
Autor:
Nir Barzilai, Radhika Muzumdar, Sigal Fishman, Gil Atzmon, Xiao Man Yang, Francine H. Einstein
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E451-E455
Insulin resistance (IR) is a hallmark of pregnancy. Because increased visceral fat (VF) is associated with IR in nonpregnant states, we reasoned that fat accretion might be important in the development of IR during pregnancy. To determine whether VF