Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Francine Gregoire"'
Autor:
Elena M. Smekalova, Maria G. Martinez, Emmanuel Combe, Anuj Kumar, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, J. Robert Dorkin, Lan Shuan Shuang, Sarah Kieft, Lauren Young, Luis Alberto Barrera, Michael S. Packer, Giuseppe Ciaramella, Barbara Testoni, Francine Gregoire, Fabien Zoulim
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102112- (2024)
Chronic hepatitis B virus (HBV) infection remains a global health problem due to the lack of treatments that prevent viral rebound from HBV covalently closed circular (ccc)DNA. In addition, HBV DNA integrates in the human genome, serving as a source
Externí odkaz:
https://doaj.org/article/079b4123912c4274a76ea24a7da66556
Autor:
Maria Guadalupe Martinez, Elena Smekalova, Emmanuel Combe, Francine Gregoire, Fabien Zoulim, Barbara Testoni
Publikováno v:
Viruses, Vol 14, Iss 12, p 2654 (2022)
Hepatitis B virus (HBV) remains a significant cause of mortality and morbidity worldwide, since chronic HBV infection is associated with elevated risk of cirrhosis and hepatocellular carcinoma. Current licensed therapies against HBV efficiently suppr
Externí odkaz:
https://doaj.org/article/bdec77eb3c174dc7bef2450a10cac13c
Autor:
Leif Carlsson, Jonathan C. Clarke, Christopher Yen, Francine Gregoire, Tamsin Albery, Martin Billger, Ann-Charlotte Egnell, Li-Ming Gan, Karin Jennbacken, Edvin Johansson, Gunilla Linhardt, Sofia Martinsson, Muhammad Waqas Sadiq, Nevin Witman, Qing-Dong Wang, Chien-Hsi Chen, Yu-Ping Wang, Susan Lin, Barry Ticho, Patrick C.H. Hsieh, Kenneth R. Chien, Regina Fritsche-Danielson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 330-346 (2018)
mRNA can direct dose-dependent protein expression in cardiac muscle without genome integration, but to date has not been shown to improve cardiac function in a safe, clinically applicable way. Herein, we report that a purified and optimized mRNA in a
Externí odkaz:
https://doaj.org/article/323a8ccca84c43bd8436f92356b5feeb
Autor:
Guanghou Shui, Jeffrey William Stebbins, Buu Duyen Lam, Wei Fun Cheong, Sin Man Lam, Francine Gregoire, Jun Kusonoki, Markus R Wenk
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19731 (2011)
BACKGROUND: Non-human primates (NHP) are now being considered as models for investigating human metabolic diseases including diabetes. Analyses of cholesterol and triglycerides in plasma derived from NHPs can easily be achieved using methods employed
Externí odkaz:
https://doaj.org/article/df27592d7e9b4b42906465a1f8a63dfb
Autor:
Xinfu Zhang, Wenqing Li, Luis A. Barrera, Francine Gregoire, Chengxiang Zhang, Xucheng Hou, Weiyu Zhao, Denise E. Sabatino, Giang N. Nguyen, Binbin Deng, Robert Dorkin, Yizhou Dong, Manmohan Singh, Jingyue Yan, Delai Chen, David W. McComb, Justin Jiang, Shi Du, Chunxi Zeng, Aalok Shah
Publikováno v:
Science Advances
Biodegradable nanomaterials effectively deliver long messenger RNAs in animal models.
Messenger RNA (mRNA) therapeutics have been explored to treat various genetic disorders. Lipid-derived nanomaterials are currently one of the most promising bi
Messenger RNA (mRNA) therapeutics have been explored to treat various genetic disorders. Lipid-derived nanomaterials are currently one of the most promising bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ee03c199d11f41ffcbc1ae3eb55a09
https://doi.org/10.1126/sciadv.abc2315
https://doi.org/10.1126/sciadv.abc2315
Autor:
Kenneth R. Chien, Susan Lin, Patrick C.H. Hsieh, Karin Jennbacken, Muhammad Waqas Sadiq, Francine Gregoire, Yu-Ping Wang, Christopher Y.T. Yen, Jonathan Clarke, Leif Carlsson, Gunilla Linhardt, Qing-Dong Wang, Regina Fritsche-Danielson, Li-Ming Gan, Edvin Johansson, Sofia Martinsson, Martin Billger, Ann-Charlotte Egnell, Nevin Witman, Barry Ticho, Tamsin Albery, Chien-Hsi Chen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 330-346 (2018)
mRNA can direct dose-dependent protein expression in cardiac muscle without genome integration, but to date has not been shown to improve cardiac function in a safe, clinically applicable way. Herein, we report that a purified and optimized mRNA in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1241b73502dc7546491692799cde0906
https://doi.org/10.1016/j.omtm.2018.04.003
https://doi.org/10.1016/j.omtm.2018.04.003
Autor:
Leif, Carlsson, Jonathan C, Clarke, Christopher, Yen, Francine, Gregoire, Tamsin, Albery, Martin, Billger, Ann-Charlotte, Egnell, Li-Ming, Gan, Karin, Jennbacken, Edvin, Johansson, Gunilla, Linhardt, Sofia, Martinsson, Muhammad Waqas, Sadiq, Nevin, Witman, Qing-Dong, Wang, Chien-Hsi, Chen, Yu-Ping, Wang, Susan, Lin, Barry, Ticho, Patrick C H, Hsieh, Kenneth R, Chien, Regina, Fritsche-Danielson
Publikováno v:
Molecular Therapy. Methods & Clinical Development
mRNA can direct dose-dependent protein expression in cardiac muscle without genome integration, but to date has not been shown to improve cardiac function in a safe, clinically applicable way. Herein, we report that a purified and optimized mRNA in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39d65eeb1fc56b4fb8171bba6d54e900
https://pubmed.ncbi.nlm.nih.gov/30038937
https://pubmed.ncbi.nlm.nih.gov/30038937
Publikováno v:
PPAR Research, Vol 2008 (2008)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::0ca705fa3efd1c8a2ef02da8348b20bf
https://doaj.org/article/d2736d8b07b540958cac2d52fbb14a44
https://doaj.org/article/d2736d8b07b540958cac2d52fbb14a44