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of 14
pro vyhledávání: '"Francine E. Brennan"'
Autor:
Yi-Zhou, Yao, Francine E, Brennan, Cristian A, Carvajal, Andrea, Vecchiola, Alejandra, Tapia-Castillo, Carlos E, Fardella, Peter J, Fuller
Publikováno v:
Steroids. 184:109037
Cortisol resistance has also been reported in the degu, Octodon degus, a New World hystricomorph endemic to central Chile. The degu is used as a model for studies of stress and diurnal rhythms, parental behaviour and female masculinization. Another N
Autor:
Francine E. Brennan, Peter J. Fuller
Publikováno v:
Endocrinology. 147:2809-2816
Aldosterone acts via the mineralocorticoid receptor to regulate gene expression. A number of aldosterone-induced genes have been characterized in the distal colon and/or the distal nephron. Using the Xenopus kidney-derived A6 cell line, the K-ras tra
Publikováno v:
Molecular and Cellular Endocrinology. 217:203-212
The isolation of aldosterone 50 years ago was a critical first step in elucidating the mechanism by which corticosteroids regulate electrolyte homeostasis. The broad principles of this mechanism involving an intracellular receptor acting on specific
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 85:389-396
The molecular mechanisms by which aldosterone regulates epithelial sodium transport in the distal colon and the distal nephron remain to be fully elucidated. Aldosterone acts via the mineralocorticoid receptor (MR) to induce the expression of genes w
Autor:
Peter J. Fuller, Francine E. Brennan
Publikováno v:
Molecular and Cellular Endocrinology. 166:129-136
The molecular mechanisms by which corticosteroids regulate epithelial sodium transport remain to be fully elucidated. Expression of the serum and glucocorticoid-regulated kinase (sgk) has recently been reported to be regulated acutely by corticostero
Publikováno v:
Molecular and cellular endocrinology. 332(1-2)
Comparison between evolutionarily distant receptors can provide critical insights into both structure and function. Sequence comparison between the mineralocorticoid receptors (MR) of the zebrafish (zMR) and human (hMR) reveals a high degree of seque
Autor:
Francine E. Brennan, Peter J. Fuller
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 26:489-491
1. Previous studies have shown that levels of CHIF mRNA are increased in the distal colon of the rat in response to corticosteroids. We have recently reported that this response occurs within 2 h of a single dose of either dexamethasone or aldosteron
Publikováno v:
Endocrinology. 148(4)
Aldosterone regulates sodium reabsorption in epithelial tissues such as the kidney and colon, via a pathway involving the activation of intracellular mineralocorticoid receptors (MR), induction of specific target genes, and a subsequent increase in s
Autor:
Marilyn B. Renfree, Jenny L. Harry, Jennifer A. Marshall Graves, Peter Koopman, Francine E. Brennan
Publikováno v:
Nature Genetics. 11:347-349
There is compelling evidence from mutation analysis and transgenesis that the SRY gene isolated from human and mouse encodes the testis-determining factor on the mammalian Y chromosome. However, how SRY achieves this function is unclear. Although mar
Publikováno v:
Pflugers Archiv : European journal of physiology. 441(1)
The molecular mechanisms by which corticosteroids affect fluid and electrolyte balance have yet to be fully elucidated. The apical amiloride-sensitive electrogenic epithelial sodium channel (ENaC) has been shown to have a central role in corticostero