Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Francine Aumont"'
Autor:
Francine Aumont, Paul Jolicoeur, James W. Kronstad, Louis Gaboury, Mathieu Goupil, Louis de Repentigny, Serge Sénéchal, Kassandre Leongson, Vincent Cousineau-Côté
Publikováno v:
Infection and Immunity. 81:1100-1113
Cryptococcus neoformans var. grubii is the most frequent cause of AIDS-associated cryptococcosis worldwide, while Cryptococcus gattii usually infects immunocompetent people. To understand the mechanisms which cause differential susceptibility to thes
Autor:
Véronique Dugas, Francine Aumont, Miriam Marquis, Paul Jolicoeur, Zaher Hanna, Daniel Lewandowski, Serge Sénéchal, Louis de Repentigny
Publikováno v:
Infection and Immunity. 74:2382-2391
Candida albicanscauses oropharyngeal candidiasis (OPC) but rarely disseminates to deep organs in human immunodeficiency virus (HIV) infection. Here, we used a model of OPC in CD4C/HIVMuttransgenic (Tg) mice to investigate the role of polymorphonuclea
Autor:
Louis de Repentigny, Jean Sébastien Ripeau, John H. Rex, Luis Ostrosky-Zeichner, Pierre Belhumeur, Francine Aumont
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3096-3100
Although the echinocandin caspofungin primarily inhibits the synthesis of cell wall 1,3-β- d -glucan, its fungicidal activity could also potentially perturb the expression of virulence factors involved in the ability of Candida albicans to cause inf
Autor:
Zaher Hanna, Marie Fiorillo, Denis G. Kay, Louis de Repentigny, Paul Jolicoeur, Francine Aumont, Jean-Sébastien Ripeau
Publikováno v:
The Journal of Infectious Diseases. 185:1103-1114
The availability of CD4C/HIV MutA transgenic (Tg) mice expressing human immunodeficiency virus type 1 in immune cells and developing an AIDS-like disease has provided the opportunity to devise a model of mucosal candidiasis that closely mimics the cl
Autor:
Pierre Belhumeur, Jean-Sébastien Ripeau, Louis de Repentigny, Francine Aumont, Marie Fiorillo
Publikováno v:
The Journal of Infectious Diseases. 185:1094-1102
To comprehensively assess the in vivo expression of Candida albicans hydrolytic enzyme genes during oropharyngeal candidiasis (OPC), a controlled sequential analysis of the temporal expression of individual members of the SAP (secretory aspartyl prot
Autor:
Francine Aumont, Paul Jolicoeur, Louis Gaboury, Louis de Repentigny, Mathieu Goupil, Vincent Cousineau-Côté, Serge Sénéchal, Zaher Hanna
Publikováno v:
BMC Immunology
Background The tissue-signaling cytokines IL-17 and IL-22 are critical to host defense against oral Candida albicans infection, by their induction of oral antimicrobial peptide expression and recruitment of neutrophils. Mucosal Th17 cells which produ
Publikováno v:
Infection and Immunity. 68:3172-3179
In order to approximate and adhere to mucosal epithelial cells, Candida must traverse the overlying mucus layer. Interactions of Candida species with mucin and human buccal epithelial cells (BECs) were thus investigated in vitro. Binding of the Candi
Publikováno v:
Microbiology. 144:2299-2310
To elucidate the implications of secreted aspartyl proteinase (Sap)2p in the pathogenesis of Candida infections, the SAP2 gene was expressed in Saccharomyces cerevisiae and overexpressed in Candida albicans. The coding region of SAP2, including its s
Evidence for degradation of gastrointestinal mucin by Candida albicans secretory aspartyl proteinase
Publikováno v:
Infection and Immunity. 64:4514-4519
A zone of extracellular digestion of the mucin layer around Candida albicans blastoconidia was observed by transmission electron microscopy in the jejunum of mice inoculated intragastrically (G. T. Cole, K. R. Seshan, L. M. Pope, and R. J. Yancey, J.
Publikováno v:
Medical Mycology. 34:401-406
Ultrastructural examinations of sites where Candida albicans invaded the bowel wall after oral intragastric inoculation of infant mice suggested that blastoconidia are capable of progressive extracellular digestion of the intestinal mucus barrier. Mi