Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Francine A. Tansey"'
Publikováno v:
Journal of Neurochemistry. 47:1061-1065
Carbonic anhydrase was assayed and carbonic an-hydrase and 5′-nucIeotidase were localized in the CNS of myelin-deficient mutant rats and normal littermates. The carbonic anhydrase specific activities were reduced by 61% and 29% in the mutants' fore
Publikováno v:
Molecular and Chemical Neuropathology. 31:161-170
Cuprizone intoxication has been used as a model for reversible demyelination in the CNS. During the course of cuprizone intoxication, the glutathione-S-transferase isoform, Pi, normally an oligodendrocytic marker, appears in reactive astrocytes (Camm
Publikováno v:
Neurochemical Research. 21:411-416
The aim of this study was to identify events that might take place in oligodendrocytes early in the process of demyelination, i.e., before the occurrence of massive loss of myelin. It was considered important to focus on demyelination and remyelinati
Publikováno v:
Annals of Neurology. 27:S75-S79
Our studies have focused on the mechanisms involved in blood-brain barrier and blood-nerve barrier alterations in inflammatory demyelinating diseases. The results support the conclusion that these diseases are initiated by delayed hypersensitivity re
Autor:
Wendy Cammer, Francine A. Tansey
Publikováno v:
Neuroscience letters. 260(3)
Carbonic anhydrase II (CAII) is expressed in oligodendrocytes, astrocytes and myelin in brains of rats and normal mice, but not in the brains of CAII-deficient mutant mice. We have transplanted mixed glial-cell suspensions from normal mouse brains, a
Autor:
Wendy Cammer, Francine A. Tansey
Publikováno v:
Neuroscience letters. 248(3)
The present study addresses a controversy over the abilities of astrocytes to perform phagocytosis. Primary glial-cell cultures were prepared from the brains of neonatal rats and were incubated with fluorescently-labeled dextran beads (molecular weig
Publikováno v:
Journal of neuroscience research. 40(4)
In the choroid plexus carbonic anhydrase II (CAII) supports the transport of bicarbonate ions, sodium ions, and water from blood to the CSF, and in the myelin sheath CAII supports compaction of myelin by stimulating cotransport of ions and water out
Autor:
Francine A. Tansey, Wendy Cammer
Publikováno v:
Brain research. 564(1)
In the rat brain hydrocortisone induces the enzyme, glycerolphosphate dehydrogenase (GPDH), during the first postnatal week. The present studies focused on a hypothetical role for glutathione-S-transferase (GST) in that phenomenon. Two forms of GST,
Autor:
Francine A. Tansey, Wendy Cammer
Publikováno v:
Journal of neurochemistry. 57(1)
The pi form of glutathione-S-transferase (GST), previously found to be oligodendrocyte associated, has also been found in myelin. In the brains of adult mice, immunocytochemical staining for a pi form of GST was observed in myelinated fibers, as well
Publikováno v:
Journal of neurochemistry. 56(1)
The results of recent immunocytochemical experiments suggest that glutamine synthetase (GS) in the rat CNS may not be confined to astrocytes. In the present study, GS activity was assayed in oligodendrocytes isolated from bovine brain and in oligoden