Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Franciele Aline Bruinsmann"'
Autor:
Aline de Cristo Soares Alves, Franciele Aline Bruinsmann, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann
Publikováno v:
Molecules, Vol 26, Iss 14, p 4127 (2021)
Bevacizumab (BCZ) is a recombinant humanized monoclonal antibody against the vascular endothelial growth factor, which is involved in the angiogenesis process. Pathologic angiogenesis is observed in several diseases including ophthalmic disorders and
Externí odkaz:
https://doaj.org/article/7d50a758c79648c482344699a94d955b
Autor:
Julieti Huch Buss, Karine Rech Begnini, Franciele Aline Bruinsmann, Taíse Ceolin, Mariana Souza Sonego, Adriana Raffin Pohlmann, Sílvia Stanisçuaski Guterres, Tiago Collares, Fabiana Kömmling Seixas
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Transitional cell carcinoma (TCC) represents the most frequent type of bladder cancer. Recently, studies have focused on molecular tumor classifications in order to diagnose tumor subtypes and predict future clinical behavior. Increased expression of
Externí odkaz:
https://doaj.org/article/eadacd007c8b46b586c125596b808943
Autor:
Franciele Aline Bruinsmann, Stefania Pigana, Tanira Aguirre, Gabriele Dadalt Souto, Gabriela Garrastazu Pereira, Annalisa Bianchera, Laura Tiozzo Fasiolo, Gaia Colombo, Magno Marques, Adriana Raffin Pohlmann, Silvia Stanisçuaski Guterres, Fabio Sonvico
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 86 (2019)
Drug delivery to the brain represents a challenge, especially in the therapy of central nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential anticancer properties that are difficult to exploit in the central nerv
Externí odkaz:
https://doaj.org/article/046312284627464cadda6ff560e0070a
Autor:
Aline de Cristo Soares Alves, Ana Maria Oliveira Battastini, Fabrício Figueiró, Silvia Stanisçuaski Guterres, Vladimir Lavayen, Fernanda Visioli, Amanda de Fraga Dias, Adriana Raffin Pohlmann, Franciele Aline Bruinsmann, Rodrigo Cé, Juliete Nathali Scholl
Publikováno v:
Nanomedicine. 16:1775-1790
Aim: To evaluate the antitumor efficacy of bevacizumab-functionalized nanocapsules in a rat glioblastoma model after the pretreatment with nanocapsules functionalized with a peptide-specific to the epidermal growth factor receptor variant III. Materi
Autor:
Franciele Aline Bruinsmann, Aline de Cristo Soares Alves, Amanda de Fraga Dias, Luiz Fernando Lopes Silva, Fernanda Visioli, Adriana Raffin Pohlmann, Fabrício Figueiró, Fabio Sonvico, Silvia Stanisçuaski Guterres
Publikováno v:
International journal of pharmaceutics. 616
Glioblastoma is the most common and lethal malignant brain tumor. Despite simvastatin (SVT) showing potential anticancer properties, its antitumoral effect against glioblastoma appears limited when the conventional oral administration route is select
Autor:
Ana Maria Oliveira Battastini, Franciele Aline Bruinsmann, Ana Conejo-García, Luiz Fernando Lopes Silva, Danieli Rosane Dallemole, Joaquín M. Campos, Amanda de Fraga Dias, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Olga Cruz-Lopez, Fabrício Figueiró
Publikováno v:
Nanomedicine (London, England). 16(23)
Aim: To develop and characterize bozepinib-loaded lipid-core nanocapsules (BZP-LNC+) as a potential treatment for glioblastoma (GBM). Methods: Characterization of nanocapsules was performed by diameter, polydispersity index, Zeta potential, pH and en
Autor:
Adriane Belló-Klein, Lali Ronsoni Zancan, Cristina Campos Carraro, Franciele Aline Bruinsmann, Claiton I. Schwertz, Adriana Raffin Pohlmann, Patrick Turck, Silvia Stanisçuaski Guterres, David Driemeier, Paulo Cavalheiro Schenkel, Alan Christhian Bahr, Alexsandra Zimmer, Karine Paese
Publikováno v:
International journal of pharmaceutics. 610
Ambrisentan (AMB) is an orphan drug approved for oral administration that has been developed for the treatment of pulmonary arterial hypertension (PAH), a chronic and progressive pathophysiological state that might result in death if left untreated.
Autor:
Raquel Cristiane Silva Barcelos, Aline Marquez Cardoso, Ruy Carlos Ruver Beck, Domenika Rubert Rossato, Tanira Aguirre, Karine Coradini, Edilene Gadelha de Oliveira, Ricardo Lorenzoni, Franciele Aline Bruinsmann, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Karine Roversi, Marilise Escobar Burger
Publikováno v:
Materials Science and Engineering: C. 96:205-217
Although phenytoin is an antiepileptic drug used in the oral treatment of epilepsy, its off-label use as a cutaneous healing agent has been studied in recent years due to the frequent reports of gingival hyperplasia after oral administration. However
Autor:
Fabiana Kömmling Seixas, Franciele Aline Bruinsmann, Gabriele Dadalt Souto, Aline de Cristo Soares Alves, Julieti Buss, Tiago Collares, Silvia Stanisçuaski Guterres, Eduarda Schultze, Adriana Raffin Pohlmann
Publikováno v:
AAPS PharmSciTech. 21(6)
Lung cancer is the most frequent type of cancer and the leading cause of cancer-related mortality worldwide. This study aimed to develop erlotinib (ELB)-loaded poly(e-caprolactone) nanocapsules (NCELB) and evaluated their in vitro cytotoxicity in A54
Autor:
Fabio Sonvico, Aline de Cristo Soares Alves, Silvia Stanisçuaski Guterres, Tanira Aguirre, Adriana Raffin Pohlmann, Franciele Aline Bruinsmann, Gustavo Richter Vaz
Publikováno v:
Molecules
Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid growth and invasion of the surrounding tissue. The current standard treatment for glioblastoma is surgery, followed by radiotherapy and concurrent chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e379a6364978474e56bbe131dc08d6c
https://doi.org/10.20944/preprints201910.0296.v1
https://doi.org/10.20944/preprints201910.0296.v1