Výsledky vyhledávání - "Franciele A. Goulart"

Nicorandil inhibits mechanical allodynia induced by paclitaxel by activating opioidergic and serotonergic mechanisms

Autor: Fábio C. Costa, Marcela I. Morais, Ivo S.F. Melo, Paulo S. A. Augusto, Márcio M. Coelho, Ângelo de Fátima, Franciele A. Goulart, Felipe F. Rodrigues, Renes R. Machado, Marcela M.G.B. Dutra, Sarah O.A.M. Costa

Publikováno v: European Journal of Pharmacology. 824:108-114

Recently, we demonstrated that nicorandil exhibits activities in models of inflammatory and nociceptive pain. In the present study, we extended this investigation by evaluating the effects of nicorandil in models of neuropathic pain induced by paclit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f136a6fe05696b0d39794f6adfc87a
https://doi.org/10.1016/j.ejphar.2018.02.014

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Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1

Autor: Marcela I. Morais, Raquel R. Menezes, Felipe F. Rodrigues, Márcio M. Coelho, Sarah O.A.M. Costa, Ivo S.F. Melo, Marcela G.M.B. Dutra, Ana Mercy S. Brito, Renes R. Machado, Franciele A. Goulart, Paulo S. A. Augusto, Adriana M. Godin

Publikováno v: European Journal of Pharmacology. 818:17-25

Leflunomide, an immunosuppressive drug approved for the treatment of patients with rheumatoid arthritis, exhibits many mechanisms which may affect the nociceptive processing. Therefore, the present study aimed to evaluate the effect induced by leflun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a5b1425febef8fabdea73942671329
https://doi.org/10.1016/j.ejphar.2017.10.026

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Clindamycin inhibits nociceptive response by reducing tumor necrosis factor-α and CXCL-1 production and activating opioidergic mechanisms

Autor: Márcio M. Coelho, Paulo S. A. Augusto, Felipe F. Rodrigues, Fábio C. Costa, Marcela I. Morais, Sarah O.A.M. Costa, Renes R. Machado, Ivo S.F. Melo, Marcela M.G.B. Dutra, Alysson Vinícius Braga, Franciele A. Goulart

Publikováno v: Inflammopharmacology. 28(2)

Clindamycin, a bacteriostatic semisynthetic lincosamide, is useful in the management of infections caused by aerobic and anaerobic Gram-positive cocci, including bacteremic pneumonia, streptococcal toxic shock syndrome and sepsis. It has been recentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97be78cc6d9fdd88dbfc0598054e0ab5
https://pubmed.ncbi.nlm.nih.gov/31768707

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Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms

Autor: Paulo S. A. Augusto, Alysson Vinícius Braga, Sarah O.A.M. Costa, Marcela I. Morais, Renes R. Machado, Márcio M. Coelho, Marcela M.G.B. Dutra, Ivo S.F. Melo, Franciele A. Goulart, Felipe F. Rodrigues, Carla R.A. Batista

Publikováno v: European Journal of Pharmacology. 858:172497

Metformin, an AMP-activated protein kinase (AMPK) activator, is an oral hypoglycemic drug widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive processing, investigating the effects induced by metformin in experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de21020fc06b56c9bd11257011c3cfe6
https://doi.org/10.1016/j.ejphar.2019.172497

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