Development of 99mTc-radiolabeled nanosilica for targeted detection of HER 2-positive breast cancer

Autor: Paolo Rainone* 1, 2, Benedetta Riva 3, Sara Belloli 1, Francesco Sudati 4, Marilena Ripamonti 1, Paolo Verderio 3, Miriam Colombo 3, Barbara Colzani 3, Maria Carla Gilardi 1, Rosa Maria Moresco 5, Davide Prosperi 3

Publikováno v: International journal of nanomedicine (Online) 12 (2017): 3447–3461. doi:10.2147/IJN.S129720
info:cnr-pdr/source/autori:Paolo Rainone* 1,2, Benedetta Riva 3*, Sara Belloli 1, Francesco Sudati 4, Marilena Ripamonti 1, Paolo Verderio 3, Miriam Colombo 3, Barbara Colzani 3, Maria Carla Gilardi 1, Rosa Maria Moresco 5, Davide Prosperi 3/titolo:Development of 99mTc-radiolabeled nanosilica for targeted detection of HER 2-positive breast cancer/doi:10.2147%2FIJN.S129720/rivista:International journal of nanomedicine (Online)/anno:2017/pagina_da:3447/pagina_a:3461/intervallo_pagine:3447–3461/volume:12

The human epidermal growth factor receptor 2 (HER2) is normally associated with a highly aggressive and infiltrating phenotype in breast cancer lesions with propensity to spread into metastases. In clinic, the detection of HER2 in primary tumors and

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