Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Francesco Santarelli"'
Autor:
Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Carl-Christian Kolbe, Steffen Wolfsgruber, Francesco Santarelli, Lisa M. Häsler, Róisín McManus, Christina Ising, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Luisa-Sophie Schneider, Xiao Wang, Josef Priller, Eike J. Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Katharina Buerger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Görß, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupow, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Annika Spottke, Alfredo Ramirez, David Mengel, Matthis Synofzik, Mathias Jucker, Eicke Latz, Frank Jessen, Michael Wagner, Michael T. Heneka, the DELCODE study group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Neuroinflammation constitutes a pathological hallmark of Alzheimer’s disease (AD). Still, it remains unresolved if peripheral inflammatory markers can be utilized for research purposes similar to blood-based beta-amyloid and neu
Externí odkaz:
https://doaj.org/article/cc42b75361934fa681bb00e0c1d00ff6
Autor:
Frederic Brosseron, Andreas Traschütz, Catherine N. Widmann, Markus P. Kummer, Pawel Tacik, Francesco Santarelli, Frank Jessen, Michael T. Heneka
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Neuroinflammation has gained increasing attention as a potential contributing factor in Alzheimer’s disease (AD) pathology. A clinical cerebrospinal fluid biomarker capable of monitoring this process during the course of the dis
Externí odkaz:
https://doaj.org/article/fe587633f3c849afa397f1f7bb288182
Autor:
Karin Lehner, Francesco Santarelli, Rudolf Vasold, Randolph Penning, Alexis Sidoroff, Burkhard König, Michael Landthaler, Wolfgang Bäumler
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92787 (2014)
Hundreds of millions of people worldwide have tattoos, which predominantly contain black inks consisting of soot products like Carbon Black or polycyclic aromatic hydrocarbons (PAH). We recently found up to 200 μg/g of PAH in commercial black inks.
Externí odkaz:
https://doaj.org/article/72107e8c3bdd4b51aeed3ba85914595e
Autor:
Roisin M. McManus, Max P Komes, Angelika Griep, Francesco Santarelli, Stephanie Schwartz, Michelle‐Amirah Khalil, Mario Lauterbach, David Gomez‐Cabrero, Jesper Tegner, Karsten Hiller, Eicke Latz, Michael T. Heneka
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Chantal M. Ferguson, Samuel Hildebrand, Bruno M.D.C Godinho, Julianna Buchwald, Dimas Echeverria, Andrew Coles, Anastasia Grigorenko, Lorenc Vanjielli, Jacquelyn Sousa, Nicholas McHugh, Matthew Hassler, Francesco Santarelli, Michael T. Heneka, Evgeny Rogaev, Anastasia Khvorova
The most common genetic risk factor for late-onset Alzheimer’s disease (AD) is the APOE4 allele, with evidence for gain- and loss-of-function mechanisms. ApoE knockout in mice abrogates AD phenotypes but causes severe atherosclerosis due to the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9c2819dfad032542f7818d565c32475
https://doi.org/10.1101/2022.06.28.498012
https://doi.org/10.1101/2022.06.28.498012
Autor:
Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Pablo García González, Róisín M. McManus, Christina Ising, Francesco Santarelli, Carl-Christian Kolbe, Lisa M. Häsler, Steffen Wolfsgruber, Marta Marquié, Mercè Boada, Adelina Orellana, Itziar de Rojas, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Arda Cetindag, Xiao Wang, Josef Priller, Eike J. Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Katharina Bürger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupov, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Charlotte E. Teunissen, Natalie L. Marchant, Annika Spottke, Mathias Jucker, Eicke Latz, Michael Wagner, David Mengel, Matthis Synofzik, Frank Jessen, Alfredo Ramirez, Agustín Ruiz, Michael T. Heneka
Publikováno v:
the DELCODE study group 2022, ' Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease ', Neuron, vol. 110, no. 6, pp. 1009-1022.e4 . https://doi.org/10.1016/j.neuron.2021.12.016
Neuron, 110(6), 1009-1022.e4. Cell Press
Neuron 110(6), 1009-1022.e4 (2022). doi:10.1016/j.neuron.2021.12.016
Neuron, 110(6), 1009-1022.e4. Cell Press
Neuron 110(6), 1009-1022.e4 (2022). doi:10.1016/j.neuron.2021.12.016
There is an urgent need to improve the understanding of neuroinflammation in Alzheimer's disease (AD). We analyzed cerebrospinal fluid inflammatory biomarker correlations to brain structural volume and longitudinal cognitive outcomes in the DELCODE s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41ef513202d55323e4fa7d6c6fae0e9
https://research.vumc.nl/en/publications/7b3bd725-fd82-4214-85cb-1b6558b53b1c
https://research.vumc.nl/en/publications/7b3bd725-fd82-4214-85cb-1b6558b53b1c
Autor:
Frank Jessen, Carl-Christian Kolbe, Sergio Castro-Gomez, Pawel Tacik, Kilian Kleemann, Eicke Latz, Francesco Santarelli, Frederic Brosseron, Michael T. Heneka
Publikováno v:
Journal of neurochemistry 157(6), 2210-2224 (2021). doi:10.1111/jnc.15175
There is growing evidence that promising biomarkers of inflammation in Alzheimer´s disease (AD) and other neurodegenerative diseases correlate strongest to levels of tau or neurofilament, indicating an inflammatory response to neuronal damage or dea
Autor:
Roisin McManus, Max P. Komes, Angelika Griep, Francesco Santarelli, Stephanie Schwartz, Juan Ramon Perea, Michelle-Amirah Khalil, Mario Lauterbach, Lea Heinemann, Titus Schlüter, Juan F. Rodriguez Alcazar, Susanne F. Schmidt, Jasper Spitzer, Peri Noori, Alberto Maillo, David Gomez-Cabrero, Jesper Tegnér, Karsten Hiller, Eicke Latz, Michael T. Heneka
Publikováno v:
SSRN Electronic Journal.
Autor:
Thomas Klockgether, Teodora Stella Wijasa, Stephanie Schwartz, Volkmar Gieselmann, Michael T. Heneka, Frederic Brosseron, Francesco Santarelli, Marc Sylvester, Nahal Brocke-Ahmadinejad
Publikováno v:
Journal of neurochemistry 152(6), 710-726 (2019). doi:10.1111/jnc.14870
Increasing evidence suggests that both synaptic loss and neuroinflammation constitute early pathologic hallmarks of Alzheimer's disease. A downstream event during inflammatory activation of microglia and astrocytes is the induction of nitric oxide sy
Autor:
Jonas J. Neher, Ildiko Racz, Julius V. Emmrich, Stephanie Schwartz, Linda Oberle, Tatsuya Manabe, Michael T. Heneka, Francesco Santarelli
Publikováno v:
Journal of neurochemistry 159(3), 525-542 (2021). doi:10.1111/jnc.15491
Sepsis-associated encephalopathy (SAE) represents diverse cerebral dysfunctions in response to pathogen-induced systemic inflammation. Peripheral exposure to lipopolysaccharide (LPS), a component of the gram-negative bacterial cell wall, has been ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f474e4e9671b306fc1eb97f9251e5b
https://pub.dzne.de/record/162891
https://pub.dzne.de/record/162891