Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Francesco Santarella"'
Autor:
Francesco Santarella, Ronaldo Jose Farias Correa do Amaral, Mark Lemoine, Domhnall Kelly, Brenton Cavanagh, Milica Marinkovic, Avi Smith, Jonathan Garlick, Fergal J. O’Brien, Cathal J. Kearney
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 10, Pp n/a-n/a (2022)
Diabetic foot ulcers (DFUs) are chronic wounds sustained by pathological fibroblasts and aberrant extracellular matrix (ECM). Porous collagen‐based scaffolds (CS) have shown clinical promise for treating DFUs but may benefit from functional enhance
Externí odkaz:
https://doaj.org/article/d5a5b9429f534a14b2a702336b6ca336
Autor:
Ronaldo J. F. C. do Amaral, Noora M. A. Zayed, Elena I. Pascu, Brenton Cavanagh, Chris Hobbs, Francesco Santarella, Christopher R. Simpson, Ciara M. Murphy, Rukmani Sridharan, Arlyng González-Vázquez, Barry O'Sullivan, Fergal J. O'Brien, Cathal J. Kearney
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Porous collagen-glycosaminoglycan (collagen-GAG) scaffolds have shown promising clinical results for wound healing; however, these scaffolds do not replace the dermal and epidermal layer simultaneously and rely on local endogenous signaling to direct
Externí odkaz:
https://doaj.org/article/0000d991955d4a609af16f641fffc949
Publikováno v:
Cells, Vol 9, Iss 10, p 2190 (2020)
The c-Jun N-terminal kinase 3 (JNK3) is the JNK isoform mainly expressed in the brain. It is the most responsive to many stress stimuli in the central nervous system from ischemia to Aβ oligomers toxicity. JNK3 activity is spatial and temporal organ
Externí odkaz:
https://doaj.org/article/793cebfab56c4f4083d9804cfd35869c
Autor:
Antonio Esposito, Lara Campana, Anna Palmisano, Francesco De Cobelli, Tamara Canu, Francesco Santarella, Caterina Colantoni, Antonella Monno, Michela Vezzoli, Giulio Pezzetti, Angelo A Manfredi, Patrizia Rovere-Querini, Alessandro Del Maschio
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59308 (2013)
Skeletal muscle remodeling in response to various noxae physiologically includes structural changes and inflammatory events. The possibility to study those phenomena in-vivo has been hampered by the lack of validated imaging tools. In our study, we h
Externí odkaz:
https://doaj.org/article/bc540e064c084ee3ba416498e5838437
Autor:
Francesco Santarella, Rukmani Sridharan, Cathal J. Kearney, Milica Marinkovic, Jonathan A. Garlick, Avi Smith
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:1803-1811
Extracellular matrix is a key component of all tissues, including skin and it plays a crucial role in the complex events of wound healing. These events are impaired in chronic wounds, with chronic inflammation and infection often present in these non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dffd7ed21a12c088c2e9112ff804d3
https://doi.org/10.1002/jbm.a.37173
https://doi.org/10.1002/jbm.a.37173
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2454
Tissue engineering solutions have been widely explored for enhanced healing of skin wounds. Diabetic foot ulcers (DFU) are particularly challenging wounds to heal for a variety of reasons, including aberrant ECM, dysregulation of vascularization, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd6f52e7484b1f8c853f1cecc4fe619c
https://pubmed.ncbi.nlm.nih.gov/33755908
https://pubmed.ncbi.nlm.nih.gov/33755908
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621189
Tissue engineering solutions have been widely explored for enhanced healing of skin wounds. Diabetic foot ulcers (DFU) are particularly challenging wounds to heal for a variety of reasons, including aberrant ECM, dysregulation of vascularization, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0ad288e3ff04cc39afa62b1da9b744
https://doi.org/10.1007/7651_2021_351
https://doi.org/10.1007/7651_2021_351
Autor:
Catherine Sirafim, Shin-Loong Soong, Renuka Sitram, Sean McGrath, Tauseef Ahmad, Cathal J. Kearney, Francesco Santarella, Shifa'a Turkistani, Ronaldo J F C do Amaral
Publikováno v:
Biomaterials Science
Natural bioactive cue profiles are generally transient with cues switching on/off to coordinate successful outcomes. Dysregulation of these sequences typically leads to disease. Successful wound healing, for example, should progress sequentially thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84149d94ba5c1bb53c6aad1c261a117
https://pubmed.ncbi.nlm.nih.gov/33226390
https://pubmed.ncbi.nlm.nih.gov/33226390
Autor:
Joanne Gerber, Elisa Tinelli, Jorge A. Pereira, Monica Ghidinelli, Klaus V. Toyka, Ueli Suter, Daniel Gerber, Shuo Lin, Luigi Tortola, Francesco Santarella, Markus A. Rüegg, Manfred Kopf, Andrea Ommer, Sven Bachofner
Publikováno v:
Human Molecular Genetics, 29 (8)
Human Molecular Genetics
Human Molecular Genetics
Some mutations affecting dynamin 2 (DNM2) can cause dominantly inherited Charcot–Marie–Tooth (CMT) neuropathy. Here, we describe the analysis of mice carrying the DNM2 K562E mutation which has been associated with dominant-intermediate CMT type B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0c82595153162878edd1a1a87ce517
https://hdl.handle.net/20.500.11850/418646
https://hdl.handle.net/20.500.11850/418646
Autor:
Fergal J. O'Brien, Rukmani Sridharan, Olga Kashpur, Francesco Santarella, Behzad Gerami-Naini, Milica Marinkovic, Ronaldo J F C do Amaral, Jonathan A. Garlick, Cathal J. Kearney, Avi Smith, Brenton Cavanagh
Publikováno v:
Advanced healthcare materials. 9(16)
Diabetic foot ulcers (DFUs) are chronic wounds, with 20% of cases resulting in amputation, despite intervention. A recently approved tissue engineering product-a cell-free collagen-glycosaminoglycan (GAG) scaffold-demonstrates 50% success, motivating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3473d7c34cb6ffe6fa3ee409252d7405
https://pubmed.ncbi.nlm.nih.gov/32597577
https://pubmed.ncbi.nlm.nih.gov/32597577