Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Francesco Paoletti"'
Autor:
Alessandra Mocali, Nunzia Della Malva, Claudia Abete, Vito Antonio Mitidieri Costanza, Antonio Bavazzano, Vieri Boddi, Luis Sanchez, Sandra Dessì, Alessandra Pani, Francesco Paoletti
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2014 (2014)
There is great interest in developing reliable biomarkers to support antemortem diagnosis of late-onset Alzheimer’s disease (AD). Early prediction and diagnosis of AD might be improved by the detection of a proteolytic dysfunction in extracts from
Externí odkaz:
https://doaj.org/article/77be9e70f06048538c52a839523bfa8b
Autor:
Anna Laurenzana, Manjola Balliu, Cristina Cellai, Maria Novella Romanelli, Francesco Paoletti
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58267 (2013)
Histone deacetylase inhibitors (HDACi) represent a promising class of epigenetic agents with anticancer properties. Here, we report that (S)-2, a novel hydroxamate-based HDACi, shown previously to be effective against acute myeloid leukemia cells, wa
Externí odkaz:
https://doaj.org/article/f5c787c6cdfc4745a1ed506b090b2528
Autor:
Maria Franca Mulas, Antonella Mandas, Claudia Abete, Sandra Dessì, Alessandra Mocali, Francesco Paoletti
Publikováno v:
Hematology Reports, Vol 3, Iss 2, Pp e19-e19 (2011)
Cholesterol is an essential constituent of all mammalian cell membranes, and its availability is therefore a prerequisite for cellular growth and other functions. Several lines of evidence are now indicating an association between alterations of chol
Externí odkaz:
https://doaj.org/article/bb833918e6df47748d5f8365510af19b
Autor:
Wilson H. Miller, Francesco Paoletti, Albert S. Baldwin, Ari Melnick, Maria Eugenia Figueroa, Filippa Pettersson, Luca A. Petruccelli, Anna Laurenzana
Supplementary Materials from Inhibition of DNA Methyltransferase Activates Tumor Necrosis Factor α–Induced Monocytic Differentiation in Acute Myeloid Leukemia Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa7448910b4388cded4a477e9533f4
https://doi.org/10.1158/0008-5472.22376087.v1
https://doi.org/10.1158/0008-5472.22376087.v1
Autor:
Wilson H. Miller, Francesco Paoletti, Albert S. Baldwin, Ari Melnick, Maria Eugenia Figueroa, Filippa Pettersson, Luca A. Petruccelli, Anna Laurenzana
Supplementary Information from Inhibition of DNA Methyltransferase Activates Tumor Necrosis Factor α–Induced Monocytic Differentiation in Acute Myeloid Leukemia Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a73b42fab32b157ec7673072b76dd5b
https://doi.org/10.1158/0008-5472.22376090.v1
https://doi.org/10.1158/0008-5472.22376090.v1
Autor:
Eugenio Torre, Matteo Lulli, Alessandro M. Vannucchi, Francesco Paoletti, Cristina Cellai, Anna Laurenzana, Manjola Balliu
Publikováno v:
Oncotarget
This work describes the effectiveness of HDAC-inhibitor (S)-2 towards colorectal cancer (CRC) HCT116 cells in vitro by inducing cell cycle arrest and apoptosis, and in vivo by contrasting tumour growth in mice xenografts. Among the multifaceted drug-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1941362233140f12a3036dd0181e3d36
http://hdl.handle.net/2158/1041458
http://hdl.handle.net/2158/1041458
Autor:
Christina D. Orru, Anna Laurenzana, Maria Dolores Cannas, Claudia Mulas, Antonio Mitidieri Costanza, Sandra Dessì, Alessandra Pani, Cristina Cellai, Paolo La Colla, Pier Luigi Cocco, A. Bavazzano, Paolo Putzu, Giacomo Diaz, Francesco Paoletti, Fabrizio Angius, Antonella Mandas, Alessandra Mocali, Claudia Abete
Publikováno v:
Journal of Alzheimer's Disease. 18:829-841
Intracellular cholesterol metabolism was reported to modulate amyloid-beta (Abeta) generation in Alzheimer's disease (AD). Results presented herein demonstrated that, like brain cells, cultured skin fibroblasts from AD patients contained more cholest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d797d4e649992bd2965183712f7e0c04
https://doi.org/10.3233/jad-2009-1193
https://doi.org/10.3233/jad-2009-1193
Autor:
Luca A. Petruccelli, Anna Laurenzana, Francesco Paoletti, Maria E. Figueroa, Albert S. Baldwin, Ari Melnick, Filippa Pettersson, Wilson H. Miller
Publikováno v:
Cancer Research. 69:55-64
Transcriptional silencing via promoter methylation of genes important for cell growth and differentiation plays a key role in myeloid leukemogenesis. We find that clinically achievable levels of 5-aza-2′-deoxycytidine (5-AZA-dC), a potent inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd77e125f1ffc8b97206e8a12d164ff
https://doi.org/10.1158/0008-5472.can-08-0245
https://doi.org/10.1158/0008-5472.can-08-0245
Autor:
Anna Laurenzana, Maria Novella Romanelli, Francesco Paoletti, Cristina Cellai, Luca Guandalini, Serena Scapecchi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5071-5074
This study concerns the synthesis of new histone deacetylase inhibitors (HDACi) characterized by a 1,4-benzodiazepine ring used as the cap, joined through an amide function or a triple bond as connection units, to a linear alkyl chain bearing the hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fd06030c213f955aa978a6d7d84606
https://doi.org/10.1016/j.bmcl.2008.07.119
https://doi.org/10.1016/j.bmcl.2008.07.119
Autor:
Sergio Bertoglio, Walter Ageno, Maurizio Paciaroni, Mario Bazzan, Stefano Mosca, Giancarlo Agnelli, Francesco Paoletti, Antonio Lazzaro, Melina Verso, Pieter Willem Kamphuisen
Publikováno v:
Internal and emergency medicine, 3(2), 117-122. Springer-Verlag Italia
Internal and Emergency Medicine, 3, 2, pp. 117-22
Internal and Emergency Medicine, 3, 117-22
Internal and Emergency Medicine, 3, 2, pp. 117-22
Internal and Emergency Medicine, 3, 117-22
Item does not contain fulltext Deep vein thrombosis of upper limb is a common complication of CVC in patients with cancer. In these patients the risk factors for CVC-related thrombosis are not completely defined. The purpose of this study was to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b48a9c099f860641a3c6ef7afde42f
https://hdl.handle.net/2066/71122
https://hdl.handle.net/2066/71122