Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Francesco P Zummo"'
Autor:
Ninon Very, Clémence Boulet, Céline Gheeraert, Alexandre Berthier, Manuel Johanns, Mohamed Bou Saleh, Loïc Guille, Fabrice Bray, Jean-Marc Strub, Marie Bobowski-Gerard, Francesco P. Zummo, Emmanuelle Vallez, Olivier Molendi-Coste, Eloise Woitrain, Sarah Cianférani, David Montaigne, Line Carolle Ntandja-Wandji, Laurent Dubuquoy, Julie Dubois-Chevalier, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-22 (2024)
Abstract Tissue injury causes activation of mesenchymal lineage cells into wound-repairing myofibroblasts (MFs), whose uncontrolled activity ultimately leads to fibrosis. Although this process is triggered by deep metabolic and transcriptional reprog
Externí odkaz:
https://doaj.org/article/7c469a228cd14e0cb8f4aa98dabc701e
Autor:
Radha Santonocito, Letizia Paladino, Alessandra Maria Vitale, Giuseppa D'Amico, Francesco Paolo Zummo, Paolo Pirrotta, Samuele Raccosta, Mauro Manno, Salvatore Accomando, Francesco D’Arpa, Francesco Carini, Rosario Barone, Francesca Rappa, Antonella Marino Gammazza, Fabio Bucchieri, Francesco Cappello, Celeste Caruso Bavisotto
Publikováno v:
Biology, Vol 13, Iss 5, p 296 (2024)
Background: Dysbiosis, influenced by poor diet or stress, is associated with various systemic diseases. Probiotic supplements are recognized for stabilizing gut microbiota and alleviating gastrointestinal issues, like irritable bowel syndrome (IBS).
Externí odkaz:
https://doaj.org/article/822ee62238d14159b422e23a2fb9bd4a
Autor:
Martina Sausa, Alberto Fucarino, Letizia Paladino, Francesco Paolo Zummo, Antonio Fabbrizio, Valentina Di Felice, Francesca Rappa, Rosario Barone, Antonella Marino Gammazza, Filippo Macaluso
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 382 (2024)
Probiotics have shown the potential to counteract the loss of muscle mass, reduce physical fatigue, and mitigate inflammatory response following intense exercise, although the mechanisms by which they work are not very clear. The objective of this re
Externí odkaz:
https://doaj.org/article/51a35aab8c3842eb9b72785200f0b632
Autor:
Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.
Externí odkaz:
https://doaj.org/article/c0d2d56ec91641b79809fad780054395
Autor:
Letizia Paladino, Francesca Rappa, Rosario Barone, Filippo Macaluso, Francesco Paolo Zummo, Sabrina David, Marta Anna Szychlinska, Fabio Bucchieri, Everly Conway de Macario, Alberto J. L. Macario, Francesco Cappello, Antonella Marino Gammazza
Publikováno v:
Biology, Vol 12, Iss 11, p 1394 (2023)
Probiotics are live microorganisms that yield health benefits when consumed, generally by improving or restoring the intestinal flora (microbiota) as part of the muco-microbiotic layer of the bowel. In this work, mice were fed with ethanol alone or i
Externí odkaz:
https://doaj.org/article/2ab33950ab874359b77ffc9aa1916d1c
Autor:
Giuditta Gambino, Giuseppe Giglia, Mario Allegra, Valentina Di Liberto, Francesco Paolo Zummo, Francesca Rappa, Ignazio Restivo, Filippo Vetrano, Filippo Saiano, Eristanna Palazzolo, Giuseppe Avellone, Giuseppe Ferraro, Pierangelo Sardo, Danila Di Majo
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1121 (2023)
Tomato fruits defined as “golden” refer to a food product harvested at an incomplete ripening stage with respect to red tomatoes at full maturation. The aim of this study is to explore the putative influence of “golden tomato” (GT) on Metabol
Externí odkaz:
https://doaj.org/article/7b79061fe843424a8e94b580a81bf9c7
Autor:
Vanessa Dubois, Céline Gheeraert, Wouter Vankrunkelsven, Julie Dubois‐Chevalier, Hélène Dehondt, Marie Bobowski‐Gerard, Manjula Vinod, Francesco Paolo Zummo, Fabian Güiza, Maheul Ploton, Emilie Dorchies, Laurent Pineau, Alexis Boulinguiez, Emmanuelle Vallez, Eloise Woitrain, Eric Baugé, Fanny Lalloyer, Christian Duhem, Nabil Rabhi, Ronald E van Kesteren, Cheng‐Ming Chiang, Steve Lancel, Hélène Duez, Jean‐Sébastien Annicotte, Réjane Paumelle, Ilse Vanhorebeek, Greet Van den Berghe, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 5, Pp 1-27 (2020)
Abstract Liver injury triggers adaptive remodeling of the hepatic transcriptome for repair/regeneration. We demonstrate that this involves particularly profound transcriptomic alterations where acute induction of genes involved in handling of endopla
Externí odkaz:
https://doaj.org/article/25e5ed41e1224b8fae474a62d14c30b5
Autor:
Danila Di Majo, Pierangelo Sardo, Giuseppe Giglia, Valentina Di Liberto, Francesco Paolo Zummo, Maria Grazia Zizzo, Gaetano Felice Caldara, Francesca Rappa, Giorgia Intili, Roelof Maarten van Dijk, Daniele Gallo, Giuseppe Ferraro, Giuditta Gambino
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 89 (2022)
Metabolic Syndrome (MetS) is an extremely complex disease. A non-balanced diet such as high-fat diet (HFD) induces metabolic dysfunction that could modify redox homeostasis. We here aimed at exploring redox homeostasis in male Wistar rats, following
Externí odkaz:
https://doaj.org/article/589dbdb073d341ff84352c701672e189
Autor:
Minna Honkanen-Scott, Kirsty S. Cullen, James Shaw, Merilin Georgiou, Penny E. Lovat, Catherine Arden, Vadivel Parthsarathy, Finbarr O'Harte, Stanislaus I Krishnanda, Francesco P Zummo
Publikováno v:
Autophagy. 18:799-815
Macroautophagy/autophagy is critical for the regulation of pancreatic β-cell mass and its deregulation has been implicated in the pathogenesis of type 2 diabetes (T2D). We have previously shown that treatment of pancreatic β-cells with the GLP1R (g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d4e206b7416dd3074c09c817ed6cb4d
https://doi.org/10.1080/15548627.2021.1956123
https://doi.org/10.1080/15548627.2021.1956123
Autor:
Marie Bobowski-Gerard, Francesco Paolo Zummo, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Cells, Vol 7, Iss 9, p 137 (2018)
Hepatic stellate cells (HSCs) serve as the main body storage compartment for vitamin A through retinyl ester (RE)-filled lipid droplets (LDs). Upon liver injury, HSCs adopt a myofibroblastic phenotype characterized by an elevated expression of extrac
Externí odkaz:
https://doaj.org/article/27b2f5bae3394313982b23519d729e00