Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Francesco Nicassio"'
Autor:
Roberto Giambruno, Elsa Zacco, Camilla Ugolini, Andrea Vandelli, Logan Mulroney, Manfredi D’Onghia, Bianca Giuliani, Elena Criscuolo, Matteo Castelli, Nicola Clementi, Massimo Clementi, Nicasio Mancini, Tiziana Bonaldi, Stefano Gustincich, Tommaso Leonardi, Gian Gaetano Tartaglia, Francesco Nicassio
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102052- (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded RNA virus, engages in complex interactions with host cell proteins throughout its life cycle. While these interactions enable the host to recognize and inhibit v
Externí odkaz:
https://doaj.org/article/6eb7df49e017486c8f0fe36a0099dc99
Autor:
Alexandre Champroux, Yang Tang, David A. Dickson, Alice Meng, Anne Harrington, Lucy Liaw, Matteo Marzi, Francesco Nicassio, Thorsten M. Schlaeger, Larry A. Feig
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTThe transgenerational effects of exposing male mice to chronic social instability (CSI) stress are associated with decreased sperm levels of multiple members of the miR-34/449 family that persist after their mating through preimplantation emb
Externí odkaz:
https://doaj.org/article/cdd068c54c754aedaf907f3afdbfdc14
Autor:
Simone Bido, Sharon Muggeo, Luca Massimino, Matteo Jacopo Marzi, Serena Gea Giannelli, Elena Melacini, Melania Nannoni, Diana Gambarè, Edoardo Bellini, Gabriele Ordazzo, Greta Rossi, Camilla Maffezzini, Angelo Iannelli, Mirko Luoni, Marco Bagicaluppi, Silvia Gregori, Francesco Nicassio, Vania Broccoli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Whether microglial activation constitutes a primary pathological event in synucleinopathies is not known. Here, the authors generated a mouse model over-expressing α-synuclein in microglial cells and found these mice developed progressive dopaminerg
Externí odkaz:
https://doaj.org/article/17b1f1f3c3604083a813e73016b6e688
Autor:
Roberto Giambruno, Francesco Nicassio
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Proximity ligation technologies are extremely powerful tools for unveiling RNA-protein interactions occurring at different stages in living cells. These approaches mainly rely on the inducible activity of enzymes (biotin ligases or peroxidases) that
Externí odkaz:
https://doaj.org/article/172bf44cf4a04271b137aad11d76f56b
Autor:
Virginia Brancato, Ilaria Brentari, Lucia Coscujuela Tarrero, Mattia Furlan, Francesco Nicassio, Michela A. Denti
Publikováno v:
Biology Open, Vol 11, Iss 10 (2022)
Since the formalization of the Central Dogma of molecular biology, the relevance of RNA in modulating the flow of information from DNA to proteins has been clear. More recently, the discovery of a vast set of non-coding transcripts involved in crucia
Externí odkaz:
https://doaj.org/article/707ca058ae974aa08505c32a19efb889
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4538 (2023)
The landscape of pervasive transcription in eukaryotic genomes has made space for the identification of thousands of transcripts that are difficult to frame in a specific functional category. A new class has been broadly named as long non-coding RNAs
Externí odkaz:
https://doaj.org/article/ecec933b372a40ffa9aba6e3dd7de8b5
Autor:
Pietro Giuseppe Mazzara, Sharon Muggeo, Mirko Luoni, Luca Massimino, Mattia Zaghi, Parisa Tajalli-Tehrani Valverde, Simone Brusco, Matteo Jacopo Marzi, Cecilia Palma, Gaia Colasante, Angelo Iannielli, Marianna Paulis, Chiara Cordiglieri, Serena Gea Giannelli, Paola Podini, Cinzia Gellera, Franco Taroni, Francesco Nicassio, Marco Rasponi, Vania Broccoli
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Friedreich’s ataxia (FRDA) is an autosomal-recessive disorder. Here the authors describe a DRG organoid from patient derived-neurons and co-culture with muscle cells to mimic the disorder in vitro and demonstrate potential correction of the phenoty
Externí odkaz:
https://doaj.org/article/b91a2f099cbf40dd993de29571b96be7
Autor:
Meritxell Pons-Espinal, Caterina Gasperini, Matteo J. Marzi, Clarissa Braccia, Andrea Armirotti, Alexandra Pötzsch, Tara L. Walker, Klaus Fabel, Francesco Nicassio, Gerd Kempermann, Davide De Pietri Tonelli
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1298-1312 (2019)
Summary: Physical exercise stimulates adult hippocampal neurogenesis and is considered a relevant strategy for preventing age-related cognitive decline in humans. The underlying mechanisms remains controversial. Here, we show that exercise increases
Externí odkaz:
https://doaj.org/article/8bf33a1bfad14af1b3cbada14f155a56
Autor:
Martina Rossi, Gabriele Bucci, Dario Rizzotto, Domenico Bordo, Matteo J. Marzi, Margherita Puppo, Arielle Flinois, Domenica Spadaro, Sandra Citi, Laura Emionite, Michele Cilli, Francesco Nicassio, Alberto Inga, Paola Briata, Roberto Gherzi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Several lncRNAs are regulated by TGF-β. Here the authors report that an intergenic lncRNA —EPR— is a component of the TGF-β signaling pathway and controls epithelial cell proliferation by altering transcription and mRNA decay of Cdkn1a. EPR ove
Externí odkaz:
https://doaj.org/article/d6f7e15deb314cbf950c9b2234270de8
Autor:
Simone Bido, Sharon Muggeo, Luca Massimino, Matteo Jacopo Marzi, Serena Gea Giannelli, Elena Melacini, Melania Nannoni, Diana Gambarè, Edoardo Bellini, Gabriele Ordazzo, Greta Rossi, Camilla Maffezzini, Angelo Iannelli, Mirko Luoni, Marco Bacigaluppi, Silvia Gregori, Francesco Nicassio, Vania Broccoli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/42495766d79f49c8bd552adffff0ed67