Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Francesco Maria Iena"'
Autor:
Francesco Maria Iena, Johanne Blanner Jul, Jens Bay Vegger, Andreas Lodberg, Jesper Skovhus Thomsen, Annemarie Brüel, Janne Lebeck
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Obesity is associated with increased plasma glycerol levels. The coordinated regulation of glycerol channels in adipose tissue (AQP7) and the liver (AQP9) has been suggested as an important contributor to the pathophysiology of type-2-diabetes mellit
Externí odkaz:
https://doaj.org/article/572d96c711e642e3bc8b54dc36ae0de7
Publikováno v:
Elnegaard, J J, Iena, F M, Herold, J & Lebeck, J 2023, ' Sex-specific effect of AQP9 deficiency on hepatic triglyceride metabolism in mice with diet-induced obesity ', Journal of Physiology . https://doi.org/10.1113/JP284188
Studies in obese rats and human cell models of non-alcoholic fatty liver disease have indicated that knockdown of the hepatic glycerol channel aquaporin 9 (AQP9) leads to decreased hepatic steatosis. However, a study in leptin receptor-deficient mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61760e7ce0317b2e765f76a2c7030c46
https://pure.au.dk/portal/da/publications/sexspecific-effect-of-aqp9-deficiency-on-hepatic-triglyceride-metabolism-in-mice-with-dietinduced-obesity(c0c8ab51-ea11-4281-8b3d-66e4380398a4).html
https://pure.au.dk/portal/da/publications/sexspecific-effect-of-aqp9-deficiency-on-hepatic-triglyceride-metabolism-in-mice-with-dietinduced-obesity(c0c8ab51-ea11-4281-8b3d-66e4380398a4).html
Autor:
Francesco Maria Iena, Joanna Kalucka, Lærke Nielsen, Esben Søndergaard, Søren Nielsen, Janne Lebeck
Publikováno v:
Iena, F M, Kalucka, J, Nielsen, L, Søndergaard, E, Nielsen, S & Lebeck, J 2022, ' Localization of aquaglyceroporins in human and murine white adipose tissue ', Histochemistry and Cell Biology, vol. 157, no. 6, pp. 623-639 . https://doi.org/10.1007/s00418-022-02090-4
The glycerol channel AQP7 facilitates glycerol efflux from adipose tissue (AT), and AQP7 deficiency has been suggested to promote obesity. However, the release of glycerol from AT is not fully blocked in AQP7-deficient mice, which suggests that eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8a32261420cfba4f2e6397061875e3
https://pure.au.dk/portal/da/publications/localization-of-aquaglyceroporins-in-human-and-murine-white-adipose-tissue(2b8e4eae-18e4-43a4-8450-d6167a89974f).html
https://pure.au.dk/portal/da/publications/localization-of-aquaglyceroporins-in-human-and-murine-white-adipose-tissue(2b8e4eae-18e4-43a4-8450-d6167a89974f).html
Autor:
Janne Lebeck, Francesco Maria Iena, Jesper Skovhus Thomsen, Johanne Blanner Jul, Annemarie Brüel, Jens Bay Vegger, Andreas Lodberg
Publikováno v:
Frontiers in Endocrinology
Iena, F M, Jul, J B, Vegger, J B, Lodberg, A, Thomsen, J S, Brüel, A & Lebeck, J 2020, ' Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver ', Frontiers in Endocrinology, vol. 11, 577650 . https://doi.org/10.3389/fendo.2020.577650
Frontiers in Endocrinology, Vol 11 (2020)
Iena, F M, Jul, J B, Vegger, J B, Lodberg, A, Thomsen, J S, Brüel, A & Lebeck, J 2020, ' Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver ', Frontiers in Endocrinology, vol. 11, 577650 . https://doi.org/10.3389/fendo.2020.577650
Frontiers in Endocrinology, Vol 11 (2020)
Obesity is associated with increased plasma glycerol levels. The coordinated regulation of glycerol channels in adipose tissue (AQP7) and the liver (AQP9) has been suggested as an important contributor to the pathophysiology of type-2-diabetes mellit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bca8c1be0ce4fcebd526a8d2ff25966
http://europepmc.org/articles/PMC7609944
http://europepmc.org/articles/PMC7609944
Publikováno v:
Iena, F M, Vegger, J B, Thomsen, J S, Brüel, A & Lebeck, J 2019, ' The Effect of High-Fat Diet on Adipose Tissue Glycerol Metabolism Is Influenced by Sex and GLP-1 Agonist Treatment ', American Diabetes Association 79th Scientific Sessions, San Francisco, United States, 07/06/2019-11/06/2019 .
Aarhus University
Aarhus University
During fasting triglyceride (TG) in adipose tissue (AT) is hydrolyzed into fatty acids and glycerol. Glycerol exits AT through the glycerol channel aquaporin 7 (AQP7). AQP7 KO mice have increased activity of AT glycerol kinase (GlyK), increased stora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::985f3886b17d617af5746c6af5454704
https://pure.au.dk/ws/files/156097864/Poster_ADA_2019.pdf
https://pure.au.dk/ws/files/156097864/Poster_ADA_2019.pdf
Publikováno v:
Diabetes. 68
During fasting triglyceride (TG) in adipose tissue (AT) is hydrolyzed into fatty acids and glycerol. Glycerol exits AT through the glycerol channel aquaporin 7 (AQP7). AQP7 KO mice have increased activity of AT glycerol kinase (GlyK), increased stora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::954f2a088c59a0f48e49ace0ac2667fe
https://doi.org/10.2337/db19-2014-p
https://doi.org/10.2337/db19-2014-p
Autor:
Janne Lebeck, Francesco Maria Iena
Publikováno v:
International Journal of Molecular Sciences
Lebeck, J & Iena, F M 2018, ' Implications of Aquaglyceroporin 7 in Energy Metabolism. ', International Journal of Molecular Sciences (Online), vol. 1, no. 19, 154 .
Aarhus University
International Journal of Molecular Sciences, Vol 19, Iss 1, p 154 (2018)
Lebeck, J & Iena, F M 2018, ' Implications of Aquaglyceroporin 7 in Energy Metabolism. ', International Journal of Molecular Sciences (Online), vol. 1, no. 19, 154 .
Aarhus University
International Journal of Molecular Sciences, Vol 19, Iss 1, p 154 (2018)
The aquaglyceroporin AQP7 is a pore-forming transmembrane protein that facilitates the transport of glycerol across cell membranes. Glycerol is utilized both in carbohydrate and lipid metabolism. It is primarily stored in white adipose tissue as part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3e06bfb1ba4a9b3d99fbf3ae7abb0f
https://pubmed.ncbi.nlm.nih.gov/29300344
https://pubmed.ncbi.nlm.nih.gov/29300344
Autor:
Francesco, Trepiccione, Francesco Maria, Iena, Laura, Catalini, Francesco Martino, Carpi, Mogens, Koed, Sebastian, Frische
Publikováno v:
Pflugers Archiv : European journal of physiology. 469(10)
The purpose of this study is to describe a low-cost and simply made instrument capable of measuring the total CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bd11e515ce63931324f3975a91fa4d5
https://pubmed.ncbi.nlm.nih.gov/28585052
https://pubmed.ncbi.nlm.nih.gov/28585052