Diastereomeric Recognition of 5’,8-cyclo-2’-Deoxyadenosine Lesions by Human Poly(ADP-ribose) Polymerase 1 in a Biomimetic Model

Autor: Annalisa Masi, Arianna Sabbia, Carla Ferreri, Francesco Manoli, Yanhao Lai, Eduardo Laverde, Yuan Liu, Marios G. Krokidis, Chryssostomos Chatgilialoglu, Maria Rosaria Faraone Mennella

Publikováno v: Cells, Vol 8, Iss 2, p 116 (2019)

5’,8-Cyclo-2’-deoxyadenosine (cdA), in the 5’R and 5’Sdiastereomeric forms, are typical non strand-break oxidative DNA lesions, induced by hydroxyl radicals, with emerging importance as a molecular marker. These lesions are exclusively repair

Externí odkaz: https://doaj.org/article/83963f27ec684b26acbaa7301cef78c7

Immobilization of Perylene‐3,4,9,10‐Tetracarboxylic Dianhydride on Hollow Polysulfone Fibers: Primary Amine Coupling and Fluorescence Reporting

Autor: Letizia Bocchi, Francesco Manoli, Laura Favaretto, Ilse Manet, Manuela Melucci, Massimo Zambianchi, Barbara Ventura

Publikováno v: ChemPlusChem 84 (2019): 1299–1304. doi:10.1002/cplu.201800681
info:cnr-pdr/source/autori:Favaretto, Laura; Manoli, Francesco; Zambianchi, Massimo; Bocchi, Letizia; Ventura, Barbara; Manet, Ilse; Melucci, Manuela/titolo:Immobilization of Perylene-3,4,9,10-Tetracarboxylic Dianhydride on Hollow Polysulfone Fibers: Primary Amine Coupling and Fluorescence Reporting/doi:10.1002%2Fcplu.201800681/rivista:ChemPlusChem/anno:2019/pagina_da:1299/pagina_a:1304/intervallo_pagine:1299–1304/volume:84

The fluorescent dye perylene-3,4,9,10-tetracarboxylic dianhydride (PBA) was immobilized onto polysulfone hollow fibers by means of a wet coating procedure. After immobilization, PBA was able to react with primary amines through a double anhydride rin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d09c41b66e872b792b5439efe83ace5
https://doi.org/10.1002/cplu.201800681

Photochemical synthesis and preliminary photophysical evaluation of a multi-component polymer enabling PDT in hypoxic conditions as novel Breast Cancer treatment

Autor: Marco Agnes, Francesco Manoli, Milo Malanga, Ilse Gert Manet

Publikováno v: Italian Photochemistry Meeting 2021, pp. PP-016, Torino, 16-18/12/2021
info:cnr-pdr/source/autori:M. Agnes, F. Manoli, M. Malanga, I. Manet/congresso_nome:Italian Photochemistry Meeting 2021/congresso_luogo:Torino/congresso_data:16-18%2F12%2F2021/anno:2021/pagina_da:PP-016/pagina_a:/intervallo_pagine:PP-016

Online Poster presentation at theITALIAN PHOTOCHEMISTRY MEETING 2021, held in Turin (Italy) on 16-17-18/12/2021. ABSTRACT: Nanotechnologies grounded on cyclodextrin (CyD)-based polymeric nanoparticles (NPs) have been accurately tailored in order to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0939340d2aa982c839bb7e5f4adbfdac
https://publications.cnr.it/doc/463300

Efficient loading of ethionamide in cyclodextrin-based carriers offers enhanced solubility and inhibition of drug crystallization

Autor: Elisabetta Pancani, Jitendra Wankar, Francesco Manoli, Gábor Benkovics, Éva Fenyvesi, Ruxandra Gref, Ilse Manet, Giuseppina Salzano, Milo Malanga

Publikováno v: International journal of pharmaceutics
531 (2017): 568–576. doi:10.1016/j.ijpharm.2017.05.041
info:cnr-pdr/source/autori:Wankar J.; Salzano G.; Pancani E.; Benkovics G.; Malanga M.; Manoli F.; Gref R.; Fenyvesi E.; Manet I./titolo:Efficient loading of ethionamide in cyclodextrin-based carriers offers enhanced solubility and inhibition of drug crystallization/doi:10.1016%2Fj.ijpharm.2017.05.041/rivista:International journal of pharmaceutics (Print)/anno:2017/pagina_da:568/pagina_a:576/intervallo_pagine:568–576/volume:531

Ethionamide (ETH) is a second line antitubercular drug suffering from poor solubility in water and strong tendency to crystallize. These drawbacks were addressed by loading ETH in β-cyclodextrin (βCyD)-based carriers. The drug was incorporated in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb33bb2dce4ff4b3e613b9992949e709
https://doi.org/10.1016/j.ijpharm.2017.05.041

Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration

Autor: Matteo Nadai, Ilse Manet, Carmen D'Angelo, Erica Salvati, Luca Pompili, Sara N. Richter, Francesco Manoli, Mauro Freccero, Valentina Pirota, Annamaria Biroccio, Filippo Doria

Publikováno v: Chemistry (Weinh., Print) 25 (2019): 11085–11097. doi:10.1002/chem.201900766
info:cnr-pdr/source/autori:Doria, Filippo; Salvati, Erica; Pompili, Luca; Pirota, Valentina; D'Angelo, Carmen; Manoli, Francesco; Nadai, Matteo; Richter, Sara N.; Biroccio, Annamaria; Manet, Ilse; Freccero, Mauro/titolo:Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration/doi:10.1002%2Fchem.201900766/rivista:Chemistry (Weinh., Print)/anno:2019/pagina_da:11085/pagina_a:11097/intervallo_pagine:11085–11097/volume:25

Naphthalene diimide (NDI) dyads exhibiting a different substitution pattern and linker length have been synthesised and evaluated as G-quadruplex (G4) ligands, by investigating their cytotoxicity in selected cell lines. The dyads with the long C-7 li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c114e75496ac20e45f9c5c73d3f1c7
https://publications.cnr.it/doc/408988