Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Francesco Lipari"'
Autor:
Darshana Jani, Robin Marsden, Michele Gunsior, Laura Schild Hay, Bethany Ward, Kyra J. Cowan, Mitra Azadeh, Breann Barker, Liching Cao, Kristin R. Closson, Kelly Coble, Sanjay L. Dholakiya, Julie Dusseault, Amanda Hays, Carina Herl, Michael E. Hodsdon, Susan C. Irvin, Susan Kirshner, Gerry Kolaitis, Nadia Kulagina, Seema Kumar, Ching Ha Lai, Francesco Lipari, Susana Liu, Keith D. Merdek, Ioana R. Moldovan, Reza Mozaffari, Luying Pan, Corina Place, Veerle Snoeck, Marta Starcevic Manning, Dennis Stocker, Magdalena Tary-Lehmann, Amy Turner, Inna Vainshtein, Daniela Verthelyi, William T. Williams, Haoheng Yan, Weili Yan, Lili Yang, Lin Yang, Jennifer Zemo, Zhandong Don Zhong
Publikováno v:
The AAPS journalReferences. 24(6)
A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity findings and expedient review by industry and health authorities. To address these key bioanalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6785f559d1c0afdbcb7a3a0839baf45
https://pubmed.ncbi.nlm.nih.gov/36307592
https://pubmed.ncbi.nlm.nih.gov/36307592
Autor:
Philippe Bourgeois, Magdalena Nutu, Henrik Zetterberg, Maria Bjerke, Francesco Lipari, Stephane Parent, Annika Öhrfelt, Ulf Andreasson, Rita Persson, Oskar Hansson, Ann Brinkmalm, Marc Mercken, Kaj Blennow, Erik Portelius, Lennart Minthon, Gunnar Brinkmalm
Publikováno v:
Brain Research. 1513:117-126
Objective: Cerebral accumulation of amyloid beta (A beta) is a pathological hallmark of Alzheimer's disease (AD). Proteolytic processing of amyloid precursor protein (APP) by alpha- or beta-secretase results in two soluble metabolites, sAPP alpha and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f871bf805cc348bbbf4602340e1b60
https://doi.org/10.1016/j.brainres.2013.03.019
https://doi.org/10.1016/j.brainres.2013.03.019
Autor:
Ulf Andreasson, Oskar Hansson, Magdalena Nutu, Francesco Lipari, Radu Constantinescu, Sara Hall, Kaj Blennow, Philippe Bourgeois, Henrik Zetterberg, Stephane Parent, Erik Portelius
Publikováno v:
NeuroMolecular Medicine. 15:169-179
Cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) reflect brain biochemistry. Using combined immunoprecipitation and mass spectrometry, we have shown that amyloid beta 1-15 (Aβ1-15) is produced by concerted β- and α-secretase cleav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8ec59189a7e6f41e47e3f33d13ddc5
https://doi.org/10.1007/s12017-012-8208-8
https://doi.org/10.1007/s12017-012-8208-8
Publikováno v:
Current Chemical Genomics
Out of the 90 human protein tyrosine kinases, 81 were assayed with short peptides derived from well-characterized [CDK1(Tyr15), IRS1(Tyr983), and JAK1(Tyr1023)] or generic [polyGlu:Tyr(4:1) and poly-Glu:Ala:Tyr(1:1:1)] substrates. As expected, the CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8936ceae7840452a311d816e6bc96a8
https://doi.org/10.2174/1875397301105010115
https://doi.org/10.2174/1875397301105010115
Publikováno v:
Biochemistry. 40:1196-1204
The E6 Zn(2+)-binding protein of high-risk human papillomaviruses (HPVs) is one of the major transforming proteins encoded by these tumor viruses. A bacterial system was used to express wild type and truncated forms of HPV-16 E6 linked to GST. The re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6058a13a5288c480d3497ae7554bbf
https://doi.org/10.1021/bi001837+
https://doi.org/10.1021/bi001837+
Autor:
Mathieu Arcand, Sophie Dahan, Lucille Beaudet, Alexandre Marcil, Philippe Roby, Francesco Lipari, Jaime Padrós, Roger Bossé
Publikováno v:
Biochemistry. 49:3213-3215
We combined oxygen channeling assays with two distinct chemiluminescent beads to detect simultaneously protein phosphorylation and interaction events that are usually monitored separately. This novel method was tested in the ERK1/2 MAP kinase pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332c52301b4a82a977837957077fd4da
https://doi.org/10.1021/bi100253p
https://doi.org/10.1021/bi100253p
Publikováno v:
Canadian Journal of Chemistry. 78:577-582
Three 2-deoxy-α-D-glucopyranosyl pyridinium tetrafluoroborates were tested for their binding affinity to a range of α-glucosidases and α-mannosidases. The α-isoquinolinium salt (11) binds approximately 275-fold more tightly to yeast α-glucosidas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171d909be49db8eda433ca110db3fff8
https://doi.org/10.1139/v00-061
https://doi.org/10.1139/v00-061
Autor:
Annette Herscovics, François Vallée, Patrick Yip, P. Lynne Howell, Barry Sleno, Francesco Lipari
Publikováno v:
The EMBO Journal. 19:581-588
Mannose trimming is not only essential for N-glycan maturation in mammalian cells but also triggers degradation of misfolded glycoproteins. The crystal structure of the class I alpha1, 2-mannosidase that trims Man(9)GlcNAc(2) to Man(8)GlcNAc(2 )isome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952c81f3c618d4f7bbb2f17ea65cf4c6
https://doi.org/10.1093/emboj/19.4.581
https://doi.org/10.1093/emboj/19.4.581
Autor:
Annette Herscovics, Francesco Lipari
Publikováno v:
Journal of Biological Chemistry. 271:27615-27622
The Saccharomyces cerevisiae α1,2-mannosidase, which removes one specific mannose residue from Man9GlcNAc2 to form Man8GlcNAc2, is a member of a family of α1,2-mannosidases with similar amino acid sequences. The yeast α1,2-mannosidase contains fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21c916c76c5d71eaa6947799186a4597
https://doi.org/10.1074/jbc.271.44.27615
https://doi.org/10.1074/jbc.271.44.27615