Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Francesco La Rocca"'
Autor:
Filomena Nozza, Gabriella Vona, Stefania Trino, Fiorella D’Auria, Francesco La Rocca, Vitina Grieco, Luciana Possidente, Luciana De Luca, Pellegrino Musto
Publikováno v:
Molecular Cytogenetics, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Background Acute promyelocytic leukemia (APL) is characterized by fusion of PML/RARα genes as a result of t(15;17)(q24;q21). APL is now one of the curable hematological malignancies thanks to molecularly targeted therapies based on all-tran
Externí odkaz:
https://doaj.org/article/bce26fd4792e4f0296b858ef9ef1635b
Autor:
Stefania Trino, Pietro Zoppoli, Angelo Michele Carella, Ilaria Laurenzana, Alessandro Weisz, Domenico Memoli, Giovanni Calice, Francesco La Rocca, Vittorio Simeon, Lucia Savino, Luigi Del Vecchio, Pellegrino Musto, Antonella Caivano, Luciana De Luca
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Abstract Background Allogeneic hematopoietic stem cell transplantation (AHSCT) is a curative therapeutic approach for different hematological malignancies (HMs), and epigenetic modifications, including DNA methylation, play a role in the reconstituti
Externí odkaz:
https://doaj.org/article/e0ec02ce47b3405ea8a4e1db069d740f
Autor:
Giovanni D’Arena, Vincenzo De Feo, Giuseppe Pietrantuono, Elisa Seneca, Giovanna Mansueto, Oreste Villani, Francesco La Rocca, Fiorella D’Auria, Teodora Statuto, Luciana Valvano, Francesca Arruga, Silvia Deaglio, Dimitar G. Efremov, Alessandro Sgambato, Luca Laurenti
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
CD200, a transmembrane type Ia glycoprotein belonging to the immunoglobulin protein superfamily, is broadly expressed on a wide variety of cell types, such as B lymphocytes, a subset of T lymphocytes, dendritic cells, endothelial and neuronal cells.
Externí odkaz:
https://doaj.org/article/33c3065724ef44f79c8ba0e619e631bd
Autor:
Francesco La Rocca, Vitina Grieco, Vitalba Ruggieri, Emanuela Zifarone, Oreste Villani, Pietro Zoppoli, Sabino Russi, Simona Laurino, Geppino Falco, Giovanni Calice, Anna Marinaccio, Maria Iole Natalicchio, Francesco Albano, Pellegrino Musto
Publikováno v:
Diagnostics, Vol 10, Iss 3, p 143 (2020)
JAK2 V617F mutational status is an essential diagnostic index in myeloproliferative neoplasms (MPNs). Although widely used for detection of JAK2 V617F mutation in peripheral blood (PB), sensitive real-time quantitative PCR (qPCR) presents some method
Externí odkaz:
https://doaj.org/article/13809abebb814e39a37fe62339b22608
Autor:
Vittorio Simeon, Katia Todoerti, Francesco La Rocca, Antonella Caivano, Stefania Trino, Marta Lionetti, Luca Agnelli, Luciana De Luca, Ilaria Laurenzana, Antonino Neri, Pellegrino Musto
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 17514-17534 (2015)
Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM) which may represent a valid model for high-risk MM. This disease is associated with a very poor prognosis, and unfortunately, it has not significantly impro
Externí odkaz:
https://doaj.org/article/c9bdc7d5651142c687177eae5126b031
Autor:
Ilaria Laurenzana, Antonella Caivano, Francesco La Rocca, Stefania Trino, Luciana De Luca, Francesca D'Alessio, Silvia Schenone, Geppino Falco, Maurizio Botta, Luigi Del Vecchio, Pellegrino Musto
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Molecular targeted therapies are based upon drugs acting on tumors by interfering with specific targets involved in growth and spread of cancer. Many targeted therapies were approved by Food and Drug Administration as standard treatment, others were
Externí odkaz:
https://doaj.org/article/626a72154ca342d08cd52f8c8fcfe89b
Autor:
Sabino Russi, Henu Kumar Verma, Simona Laurino, Pellegrino Mazzone, Giovanni Storto, Anna Nardelli, Pietro Zoppoli, Giovanni Calice, Francesco La Rocca, Alessandro Sgambato, Valeria Lucci, Geppino Falco, Vitalba Ruggieri
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3736 (2019)
Despite the significant recent advances in clinical practice, gastric cancer (GC) represents a leading cause of cancer-related deaths in the world. In fact, occurrence of chemo-resistance still remains a daunting hindrance to effectiveness of the cur
Externí odkaz:
https://doaj.org/article/5df40d72be5e48e191c86977190af539
Autor:
Giovanni D'Arena, Roberto Guariglia, Francesco La Rocca, Stefania Trino, Valentina Condelli, Laura De Martino, Vincenzo De Feo, Pellegrino Musto
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
The clinical course of chronic lymphocytic leukemia (CLL) may be complicated at any time by autoimmune phenomena.The most common ones are hematologic disorders, such as autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP). Pure red ce
Externí odkaz:
https://doaj.org/article/24d32ca522ff4fc6bbf5d0b06dc988c5
Autor:
Francesco La Rocca, Pellegrino Musto
Publikováno v:
Expert Review of Hematology. 13:501-517
Introduction: Monoclonal antibodies (MoAbs) are rapidly changing the therapeutic scenario of multiple myeloma. Most of the available data, however, come from studies performed in patients with relapsed or refractory disease.Area covered: Here, the mo
Autor:
Gabriella Vona, Pellegrino Musto, Filomena Nozza, Fiorella D'Auria, Francesco La Rocca, Vitina Grieco, Luciana De Luca, Stefania Trino, Luciana Possidente
Publikováno v:
Molecular Cytogenetics, Vol 12, Iss 1, Pp 1-5 (2019)
Molecular Cytogenetics
Molecular Cytogenetics
Background Acute promyelocytic leukemia (APL) is characterized by fusion of PML/RARα genes as a result of t(15;17)(q24;q21). APL is now one of the curable hematological malignancies thanks to molecularly targeted therapies based on all-trans retinoi